Biological material for medical catheter and preparation method thereof

A technology of biomaterials and medical catheters, applied in the direction of catheters, etc., to achieve good application prospects, simple process, and stable performance

Inactive Publication Date: 2016-12-21
何仁英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, there is still a big gap between the current biomedical materials and people's real expectations and requirements.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Weigh 15 parts of butyl cyanoacrylate, 5 parts of divinylbenzene, 1 part of polyvinyl alcohol, 11 parts of polyurethane, 7 parts of polyethylene terephthalate, 6 parts of collagen, 3 parts of calcium lignosulfonate, 2 parts of hydroquinone, 5 parts of citrate, 2 parts of ethylenediamine, 1 part of gelatin, 2 parts of magnesium carbonate, 1 part of silicon dioxide, 4 parts of sorbitol, tert-butyl 3 parts of hydroquinone, 2 parts of ethylene oxide, 3 parts of hexenyl bis stearamide;

[0021] (2) Add butyl cyanoacrylate, divinylbenzene, polyvinyl alcohol, polyurethane, and polyethylene terephthalate into the melting furnace, vacuumize to 0.02MPa, add nitrogen, and the reaction temperature is 750°C. The reaction time is 15 minutes, the temperature is lowered to 550°C, collagen, calcium lignosulfonate, and tertiary butylhydroquinone are added, stirred evenly and then kept for 10 minutes to obtain a high-temperature mixture;

[0022] (3) Add hydroquinone, citrate, ethyle...

Embodiment 2

[0027] (1) Weigh 17 parts of butyl cyanoacrylate, 7 parts of divinylbenzene, 2 parts of polyvinyl alcohol, 12 parts of polyurethane, 9 parts of polyethylene terephthalate, 9 parts of collagen, 5 parts of calcium lignosulfonate, 3 parts of hydroquinone, 6 parts of citrate, 3 parts of ethylenediamine, 2 parts of gelatin, 3 parts of magnesium carbonate, 2 parts of silicon dioxide, 5 parts of sorbitol, propyl gallate 5 parts of ester, 3 parts of iodophor solution, 5 parts of zinc stearate;

[0028] (2) Add butyl cyanoacrylate, divinylbenzene, polyvinyl alcohol, polyurethane, and polyethylene terephthalate into the melting furnace, vacuumize to 0.03MPa, add nitrogen, and the reaction temperature is 750°C. The reaction time is 30 minutes, the temperature is lowered to 550°C, collagen, calcium lignosulfonate, and propyl gallate are added, stirred evenly and then kept for 10 minutes to obtain a high-temperature mixture;

[0029] (3) Add hydroquinone, citrate, ethylenediamine, gelatin...

Embodiment 3

[0034] (1) Weigh 19 parts by weight of butyl cyanoacrylate, 8 parts of divinylbenzene, 4 parts of polyvinyl alcohol, 14 parts of polyurethane, 10 parts of polyethylene terephthalate, 12 parts of collagen, 7 parts of calcium lignosulfonate, 5 parts of hydroquinone, 8 parts of citrate, 5 parts of ethylenediamine, 3 parts of gelatin, 3 parts of magnesium carbonate, 2 parts of silicon dioxide, 8 parts of sorbitol, dibutyl 7 parts of hydroxytoluene, 4 parts of glutaraldehyde, 8 parts of polyethylene glycol;

[0035] (2) Add butyl cyanoacrylate, divinylbenzene, polyvinyl alcohol, polyurethane, and polyethylene terephthalate into the melting furnace, vacuumize to 0.03MPa, add nitrogen, and the reaction temperature is 750°C. The reaction time is 25 minutes, the temperature is lowered to 550°C, collagen, calcium lignosulfonate, and dibutyl hydroxytoluene are added, stirred evenly and then kept for 10 minutes to obtain a high-temperature mixture;

[0036] (3) Add hydroquinone, citrate,...

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PUM

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Abstract

The invention discloses a biological material for a medical catheter. The biological material is prepared from the following raw materials in parts by weight: 15-20 parts of n-butyl cyanoacrylate, 5-10 parts of divinyl benzene, 1-5 parts of polyvinyl alcohol, 11-15 parts of polyurethane, 7-11 parts of polyethylene glycol terephthalate, 6-14 parts of collagen, 3-8 parts of calcium lignosulphonate, 2-6 parts of hydroquinone, 5-9 parts of citrate, 2-6 parts of ethylenediamine, 1-4 parts of gelatin, 2-4 parts of magnesium carbonate, 1-3 parts of silicon dioxide, 4-9 parts of sorbitol, 3-8 parts of an antioxidant, 2-5 parts of a disinfectant and 3-9 parts of a dispersing agent. The biological material for a medical catheter has stable performance and good durability, and is applicable to various biological environments and various medical catheters. Furthermore, the invention further discloses a method for preparing the biological material for a medical catheter.

Description

technical field [0001] The invention relates to the field of biological materials, in particular to a medical catheter biological material and a preparation method thereof. Background technique [0002] So far, more than a thousand kinds of biomaterials have been studied in detail, and dozens of them are widely used in clinical medicine, involving various fields of materials science. The main driving force for the rapid development of biomedical materials comes from the aging population, the increase of young and middle-aged trauma, the increase of patients with difficult diseases and the development of high technology. The acceleration of population aging process and human pursuit of health and longevity have stimulated the demand for biomedical materials. At present, the focus of research on biomedical materials is to find biomedical materials with better tissue compatibility, degradability, corrosion resistance, durability and multi-purpose under the premise of ensurin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L29/04A61L29/06A61L29/14
CPCA61L29/041A61L29/045A61L29/046A61L29/06A61L29/14C08L29/04C08L75/04C08L67/02C08L89/00
Inventor 何仁英
Owner 何仁英
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