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Traditional Chinese medicine capsule for treating ischemic stroke

A technology of ischemic stroke and traditional Chinese medicine capsules, which is applied in capsule delivery, medical raw materials derived from arthropods, medical raw materials derived from leeches/worms, etc., which can solve the problems of unreasonable compatibility of prescriptions, weakened therapeutic effect, and enhanced drug toxicity, etc. problems, to achieve the effect of improving treatment efficiency, lowering blood lipids, and alleviating nerve defects

Inactive Publication Date: 2016-12-21
秦月霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, doctors used the treatment principles of simply reducing phlegm, promoting blood circulation, or tonifying deficiency. It was difficult to treat comprehensively with only a few medicines, and the curative effect was not good. treat
In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When used in combination, it may not only produce synergistic drug effects, but also may produce antagonistic effects, which will lead to weakening of drug therapeutic effect or treatment failure. Some drugs in combination will also increase drug toxicity and cause adverse reactions; Enhanced, but when the therapeutic effect is excessively enhanced, it will exceed the body's ability to tolerate it, and it can also cause adverse reactions and even endanger patients.
Some of the research is to prepare traditional Chinese medicine prescriptions in order to treat ischemic stroke. The most common problem is the unreasonable compatibility of the prescriptions, often only from the individual functions and indications of some single or compound medicines and certain pharmacodynamic indicators. According to the theory of traditional Chinese medicine, the taste of prescriptions can be added or subtracted at will, resulting in unreasonable prescriptions, which contradicts the theory of traditional Chinese medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Weighing: 7 grams of melon seeds, 6 grams of Dengtai leaves, 5 grams of opposite leaves, 10 grams of Chuanxiong, 5 grams of notopterygium, 10 grams of ash tree seeds, 9 grams of ivy, 11 grams of Nigella seeds, 5 grams of earthworm, cassia seeds 5 grams, 5 grams of silkworm, 5 grams of Polygonatum, 6 grams of Rolling Mountain Pearl, 5 grams of Astragalus, 5 grams of Salvia, 5 grams of Jushishi, 5 grams of Scorpion, 5 grams of Holly Leaf, 5 grams of Licorice, 12 grams of leeches, 5 grams of naqigen, 5 grams of Shichangpu, 5 grams of pig's ginseng, 5 grams of Erye Linglan, and 5 grams of Puxian vegetables.

[0046] The preparation method is as follows: remove impurities from the above medicinal materials, mix them, put them in a drying oven and dry them at a temperature of 120°C, grind them into fine powders of 100-130 meshes, put them into capsules at 0.5g / capsule after ultraviolet disinfection, and obtain finished product.

[0047] Usage and dosage: Oral, 2 times a day,...

Embodiment 2

[0064] Weighing: 7 grams of melon seeds, 6 grams of Dengtai leaves, 5 grams of opposite leaves, 10 grams of Chuanxiong, 5 grams of Qianghuo, 11 grams of Nigella seeds, 5 grams of Dilong, 5 grams of Cassia seeds, 5 grams of Bombyx mori, and 5 grams of Polygonatum , 6 grams of rolling mountain pearls, 5 grams of astragalus, 5 grams of salvia miltiorrhiza, 5 grams of scorpion, 5 grams of holly leaves, 5 grams of licorice, 12 grams of leeches, 5 grams of anarch root, 5 grams of calamus, 5 grams of pig's ginseng, 5 grams of two-leaf tongue lip orchid, and 5 grams of Puxian vegetable. The preparation method is the same as in Example 1.

[0065] Among the 10 ischemic stroke patients selected from the traditional Chinese medicine capsules made in Example 2 of the present invention, 6 cases were basically cured, 3 cases were improved, 1 case was not cured, and 0 cases had adverse reactions. The basic cure rate was 60%, and the total effective rate was 90%. . The cured patients were f...

Embodiment 3

[0067] Weighing: 6 grams of Dengtai leaves, 5 grams of opposite leaves, 10 grams of Chuanxiong, 5 grams of notopterygium, 10 grams of ash, 9 grams of ivy, 11 grams of black cumin, 5 grams of earthworm, 5 grams of cassia, and silkworm 5 grams, 5 grams of sealwort, 6 grams of rolling pearl, 5 grams of astragalus, 5 grams of salvia miltiorrhiza, 5 grams of scorpion, 5 grams of holly leaves, 5 grams of licorice, 12 grams of leeches, 5 grams of calamus, pig 5 grams of ginseng and 5 grams of Puxian vegetables. The preparation method is the same as in Example 1.

[0068] Among the 10 patients with ischemic stroke who selected the traditional Chinese medicine capsules made in Example 3 of the present invention, 5 cases were basically cured, 3 cases were improved, 2 cases were not cured, 0 cases had adverse reactions, the basic cure rate was 50%, and the total effective rate was 80%. %. The cured patients were followed up for 24 months, and 2 cases relapsed.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine capsule for treating ischemic stroke, wherein the traditional Chinese medicine capsule is prepared from the following Chinese herbs by weight: 7 parts of semen melo, 6 parts of folium alstoniae scholaris, 5 parts of hedyotis uncinella, 10 parts of ligusticum chuanxiong hort, 5 parts of rhizoma et radix notopterygii, 10 parts of fraxinus chinensis seed, 9 parts of sinomenium acutum, 11 parts of nigella damascena seed, 5 parts of earthworm, 5 parts of semen cassiae, 5 parts of stiff silkworm, 5 parts of polygonatum sibiricum, 6 parts of glomeris nipponica kishida, 5 parts of milkvetch root, 5 parts of salvia miltiorrhiza, 5 parts of anacardium occidentalie, 5 parts of scorpion, 5 parts of ilex chinensis sims leaf, 5 parts of licorice root, 12 parts of leech, 5 parts of the root of pyrethrum cinerariifoliumc, 5 parts of acorus tatarinowii, 5 parts of the herb of platanthera minor (miq.) reichb. f, 5 parts of platanthera chlorantha cust. ex rchb, and 5 parts of cardamine macrophylla willd. According to the present invention, clinical experiment results prove that the Chinese herbs are subjected to the reasonable compatibility, such that the ischemic stroke can be effectively treated, the complications can be effectively reduced, and the good effects of whole regulation and long-term effect can be achieved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine capsule, in particular to a traditional Chinese medicine capsule for treating ischemic stroke. Background technique [0002] Ischemic stroke refers to focal ischemic necrosis or softening of brain tissue caused by brain tissue blood supply disturbance, ischemia, and hypoxia. It has the characteristics of high incidence, high mortality, and high disability rate. Frequently occurring diseases. In the past, doctors used the treatment principles of simply reducing phlegm, promoting blood circulation, or tonifying deficiency. It was difficult to treat comprehensively with only a few medicines, and the curative effect was not good. treat. In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When us...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/48A61P9/10A61K35/648A61K35/646A61K35/64A61K35/62
CPCA61K36/898A61K9/48A61K35/62A61K35/63A61K35/646A61K35/648A61K36/185A61K36/22A61K36/236A61K36/237A61K36/24A61K36/28A61K36/31A61K36/42A61K36/481A61K36/482A61K36/484A61K36/537A61K36/59A61K36/63A61K36/71A61K36/74A61K36/888A61K36/8969A61K2300/00
Inventor 秦月霞其他发明人请求不公开姓名
Owner 秦月霞
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