Liquid fermentation culture medium formula capable of improving biomass of cordyceps cicadae fungi and content of active ingredient

Abstract

The invention discloses a liquid fermentation culture medium formula capable of improving the biomass of cordyceps cicadae fungi and the content of an active ingredient. Water is used as a solvent and a culture medium is prepared from: 30g / L to 40g / L of sucrose, 15g / L to 25g / L of peptone, 0.5g / L to 1.5g / L of KH2PO4 and 0.5g / L to 1g / L of MgSO4 7H2O. A fermentation culture medium is subjected to design optimization, and an optimal carbon source, nitrogen source and inorganic salt and corresponding concentrations are obtained; the biomass of the cordyceps cicadae fungi and the content of the active ingredient, namely cordycepic acid, can be greatly improved.

Description

technical field [0001] The invention relates to microbial fermentation, in particular to a liquid fermentation medium formula for increasing the biomass and active ingredient content of cicadae fungus. Background technique [0002] Cicada is also known as Cicada Cordyceps, Cicada Velvet, Hu Chan and so on. "Compendium of Materia Medica" records: the cicada flower comes out of the middle of Sichuan, and there is a corner on the cicada, which is like a crown of flowers. Cicadae is produced in Jiangsu, Zhejiang, Fujian, Sichuan, Yunnan and other places. It is cold in nature, sweet in taste, and non-toxic. Folks are used to treat symptoms such as blurred vision and children crying at night due to convulsions. Cicadae is rich in protein, amino acid, fungal polysaccharide and physiologically active substances. It has many functions such as inhibiting tumor, analgesic and antipyretic, calming and improving eyesight. It also has the functions of lowering blood pressure, heart rate...

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Problems solved by technology

[0004] At present, there are problems in the use of cicadae, such as limited resources, difficulty in manual collection, unknown functional active components, unclear mechanism of action, and even impure raw materials, which have become a big obstacle for the traditional Chinese medicine of cicadae to go to the world. And because the cicada is a complex formed by fungi parasitic in the nymph of the bamboo cicada, it grows in a specific environment and host, so the resources are scarce, and the long-term excavation of the resources is becoming exhausted, and it has become a rare medicine.

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