Preparation method of medicinal broken-wall slices

A technology of broken-wall decoction pieces and granulator, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, bulk transportation, etc., which can solve the problem of no treatment method provided for biological limits, unfavorable rapid dissolution of medicinal active ingredients, and unsuitable medicinal materials And other problems, to ensure the safety and efficacy of medication, moderate tightness, easy to dry effect

Inactive Publication Date: 2016-11-23
湖南盟合投资管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] According to the current technology, the prepared broken-walled decoction pieces are not only fast, but also have small particles, which are difficult to dissolve in the actual use process, which is not conducive to the rapid dissolution of medicinal ingredients; medicinal materials can only be sorted and sliced, and medicinal materials that require special processing Not applicable; no treatment is provided for whether the coarse powder entering the clean area meets the biological limit

Method used

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  • Preparation method of medicinal broken-wall slices
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  • Preparation method of medicinal broken-wall slices

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Coix Seed Broken Wall Decoction Pieces

[0033] 1) Medicinal material treatment: pick and clean / process the coix seed medicinal material, dry the medicinal material until the water content of the medicinal material is below 10%, and crush the medicinal material into small particles of about 10 mesh with a 10-mesh sieve; further 100-mesh The pulverizer of the sieve is pulverized to obtain a coarse powder of medicinal materials of 80 to 120 mesh;

[0034] 2) Intermittent sterilization: Coix seed coarse powder is placed in a constant temperature and humidity box with a thickness of about 10mm, set at a temperature of 65°C (actual temperature is 60-70°C), and kept dry and sterilized for 8 hours; the treated coarse powder of medicinal materials Maintain at a temperature of 25°C and a relative humidity of 75% for 12 hours; then adjust the temperature of the constant temperature and humidity box to 35°C and maintain a relative humidity of 88% for 24 hours; change the set tempe...

Embodiment 2

[0040] Coix Seed Broken Wall Decoction Pieces

[0041] 1) Treatment of medicinal materials: pick and clean / process Coix seed medicinal materials, dry them until the water content of the medicinal materials is below 10%, and crush the medicinal materials into small particles of about 10 mesh with a 10-mesh sieve; further 100-mesh sieve 80-120 mesh medicinal material coarse powder is obtained by pulverizing with a special pulverizer;

[0042] 2) Intermittent sterilization: Coix seed coarse powder is placed in a constant temperature and humidity box with a thickness of about 5mm, set at a temperature of 70°C (actual temperature is 65-75°C), and kept dry and sterilized for 4 hours; the treated coarse powder of medicinal materials Maintain at a temperature of 20°C and a relative humidity of 70% for 15 hours; then adjust the temperature of the constant temperature and humidity box to 33°C and maintain a relative humidity of 83% for 8 hours; change the set temperature to 65°C (the ac...

Embodiment 3

[0048] Cinnamon Broken Drink Pieces

[0049] 1) Medicinal material processing: the cinnamon medicinal material is sorted, cleaned / processed, and dried until the water content of the medicinal material is below 10%, and the medicinal material is broken into small particles of about 10 mesh by a mechanical crusher with a 10-mesh sieve; further 100-mesh sieve Pulverize with a pulverizer to obtain 80-120 mesh medicinal material coarse powder;

[0050] 2) Intermittent sterilization: Put the coarse cinnamon powder in a constant temperature and humidity box with a thickness of about 30mm, set the temperature at 75°C (the actual temperature is 70-80°C), and keep it dry and sterilized for 4 hours; The temperature is 25°C and the relative humidity is 75% for 24 hours; then the temperature of the constant temperature and humidity box is adjusted to 40°C and the relative humidity is 80% for 12 hours; Set the temperature at 80°C (the actual temperature is 75-85°C), keep it dry and sterili...

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Abstract

The invention provides a preparation method of medicinal broken-wall slices. Adopted medicinal materials undergo picking and cleaning / processing, drying, crushing, smashing by using a 100-mesh smashing machine, batch-type sterilization, wall breaking, soft material making, granulation and granule drying to prepare the broken-wall slices, and the prepared broken-wall slices are good in granule shape and moderate in compactness. In addition, the prepared granules are easy to dry and quick to dissolve and disperse and are easy to disperse when a user takes the slices, the batch-type sterilization makes the medicinal slices to meet the microbial limit requirements, and the problem that at present, medicinal broken-wall slices in the market are difficult to dissolve and the microbial limit is difficult to reach is solved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine treatment, in particular to a method for preparing broken-wall decoction pieces. Background technique [0002] Ultrafine pulverization technology is a new technology developed rapidly in recent years. Most of the active ingredients in Chinese herbal medicines are distributed in the cells. When decocting conventional decoction pieces, only part of the active ingredients can be released. About 86.7% of the cell wall breaking rate will improve the dissolution of the active ingredients in the medicinal materials, greatly enhance its efficacy, and the utilization rate of the active ingredients will be above 90%, so as to reduce the amount of medicinal materials used and protect the medicinal materials resources. The quality increases the efficacy. [0003] CN200610122171.7 discloses a method for processing Chinese medicinal material wall-breaking powder. The processing steps are:...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K36/54A61K9/16
CPCA61K36/8994A61K9/16A61K36/54A61K2236/13A61K2236/15A61K2236/17
Inventor 杨记宗朱瑞清杨雅欣肖志群张小春
Owner 湖南盟合投资管理有限公司
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