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Traditional Chinese medicine for treating systemic lupus erythematosus and preparation method and application thereof

A systemic technology for lupus erythematosus, applied in the field of medicine, can solve the problems of easy recurrence of the disease and obvious adverse drug reactions, etc., achieve the effect of no toxic side effects, improve the main immunological indicators, and achieve quick results

Inactive Publication Date: 2016-11-16
陈洪晓
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, western medicine immunosuppressants and hormones are the main treatments. Although western medicine can control the occurrence and development of the disease to a certain extent, the adverse drug reactions are obvious, and the disease is prone to relapse after stopping the medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] In the embodiment of the present invention, a traditional Chinese medicine for treating systemic lupus erythematosus is composed of the following raw materials in parts by weight: 15 parts of Bai Ying, 20 parts of Bianzhucai, 1 part of Osmanthus fragrans root, 7 parts of Shenjincao, 23 parts of Sanbaicao.

[0024] Grind the grass and bletilla, pass through a 80-mesh sieve, add 75% ethanol solution with 11 times the mass of the two, heat and stir at 62°C for 1.8h, then heat and stir at 68°C for 3.5h, filter to get the filtrate . Pulverize the flat bamboo and three white grasses, pass through a 100-mesh sieve, add citric acid alcohol solution with 6 times the quality of the two to extract twice, the mass content of citric acid in the citric acid alcohol solution is 5%, and the extraction temperature is 75 °C, the leaching time is 2.5 h, the extracts are combined and concentrated to 22% of the original volume to obtain a concentrated solution. Grind the Osmanthus fragran...

Embodiment 2

[0026] In the embodiment of the present invention, a traditional Chinese medicine for treating systemic lupus erythematosus is composed of the following raw materials in parts by weight: 23 parts of Bai Ying, 28 parts of Bianzhucai, 8 parts of Osmanthus fragrans root, 15 parts of Shenjincao, 31 parts of Sanbaicao.

[0027] Grind and sieve through a 80-mesh sieve, add 75% ethanol solution with 11 times the weight of the two, heat and stir at 65°C for 2.0h, then heat and stir at 70°C for 4h, and filter to get the filtrate. Pulverize the flat bamboo and three white grasses, pass through a 100 mesh sieve, add citric acid alcohol solution with 6 times the quality of the two to extract twice, the mass content of citric acid in the citric acid alcohol solution is 6%, and the extraction temperature is 78 °C, the leaching time is 2.8h, the leaching solution is combined and concentrated to 25% of the original volume to obtain a concentrated solution. Grind the Osmanthus fragrans root, ...

Embodiment 3

[0029] In the embodiment of the present invention, a traditional Chinese medicine for treating systemic lupus erythematosus is composed of the following raw materials in parts by weight: 17 parts of Bai Ying, 22 parts of Bianzhucai, 3 parts of Osmanthus fragrans root, 9 parts of Shenjincao, 25 parts of Sanbaicao.

[0030] Grind the Herba chinensis and Bai Ying, pass through a 80-mesh sieve, add 75% ethanol solution with 11 times the mass of the two, heat and stir at 63°C for 1.9h, then seal, heat and stir at 69°C for 3.8h, filter to get the filtrate . Pulverize the flat bamboo and three white grasses, pass through a 100-mesh sieve, add citric acid alcohol solution with 6 times the quality of the two to extract twice, the mass content of citric acid in the citric acid alcohol solution is 5.5%, and the extraction temperature is 76 °C, the leaching time is 2.6h, the extracts are combined and concentrated to 24% of the original volume to obtain a concentrated solution. Grind the...

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Abstract

The invention discloses a traditional Chinese medicine for treating the systemic lupus erythematosus and a preparation method and application thereof. The traditional Chinese medicine is prepared from, by weight, 15-23 parts of solanum lyratum, 20-28 parts of Tofieldia divergens Bur. et Fra-nch., 1-8 parts of root of Dichotomy Forked Fern, 7-15 parts of common clubmoss herb and 23-31 parts of Chinese lizardtail rhizome or herb. Common clubmoss herb and solanum lyratum are smashed and sieved and added to a 75% ethyl alcohol solution to be heated and stirred, and filtering is conducted to obtain filtrate; Tofieldia divergens Bur. et Fra-nch. and Chinese lizardtail rhizome or herb are smashed and sieved and added to a citric acid alcoholic solution for two times of extraction, and concentrating is conducted to obtain a concentrated solution; root of Dichotomy Forked Fern is smashed and sieved and added to a sodium bicarbonate water solution to be heated and stirred, and drying is conducted to obtain powder of root of Dichotomy Forked Fern; the filtrate and the concentrated solution are mixed, heated and stirred, then the powder of root of Dichotomy Forked Fern is added to be stirred and ultrasonically processed, and then the traditional Chinese medicine is obtained. The traditional Chinese medicine has a good effect on the systemic lupus erythematosus and is short in treatment course, rapid in effect and free of toxic and side effects, intestine adverse reaction can not be caused, both symptoms and root causes are treated, and relapse does not easily happen after cure.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine for treating systemic lupus erythematosus and its preparation method and application. Background technique [0002] Systemic lupus erythematosus (SLE) is an autoimmune inflammatory connective tissue disease that mostly occurs in young women and involves multiple organs. Early, mild and atypical cases are increasing day by day. Some severe patients (except those with diffuse proliferative glomerulonephritis) can sometimes relieve themselves. Some patients show a "transient" attack, and the disease can disappear completely after a short course of several months. Under the interaction of various factors such as genetic factors, environmental factors, and estrogen levels, T lymphocytes decrease, T suppressor cell function decreases, B cells proliferate excessively, and a large number of autoantibodies are produced, which combine with corresponding aut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P37/02
CPCA61K36/81A61K36/11A61K36/78A61K36/896A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 陈洪晓熊瑛
Owner 陈洪晓
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