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Analgesic and preparation method thereof

A technology of analgesic agent and raw material medicine, which is applied in the field of traditional Chinese medicine acupoint injection analgesic agent and its preparation for relieving bone disease pain, which can solve the problems affecting the functional activities of shoulder joints, and achieve definite therapeutic effect, reliable safety and compatibility. precise effect

Inactive Publication Date: 2016-10-26
孙文朋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

If it is not treated effectively, it may seriously affect the functional activities of the shoulder joint

Method used

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  • Analgesic and preparation method thereof
  • Analgesic and preparation method thereof
  • Analgesic and preparation method thereof

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preparation example Construction

[0029] The present invention also provides the preparation method of above-mentioned injection, it comprises:

[0030] In the first step, each bulk drug component is weighed separately, cleaned, mixed together according to the weight parts, and 80% ethanol with an alcohol concentration of 6 to 8 times the mass of the obtained mixture is added, and heated to reflux for 5 After one hour, extract and filter to obtain the first filtrate; dissolve the filter residue with ethanol with 80% alcohol concentration 4 times the mass of the obtained mixture again, heat and reflux for 3 hours and then extract and filter to obtain the second filtrate; For the first filtrate and the second filtrate, ethanol is recovered under reduced pressure and concentrated until the concentration of the medicinal solution is 0.8g crude drug / mL, and the D101 macroporous adsorption resin is used for eluting. The volume of the resin is 5 times the volume of the concentrated medicinal solution. Elute with deio...

Embodiment 1

[0052] Embodiment 1 Injection 1

[0053]Fangji 10g, Tugucao 30g, Corydalis 30g, Evodia 12g, Wulingzhi 15g, Myrrh 15g, Sea cucumber 15g, Smilax 30g, Tianzhuhuang 10g, pine knot 10g, Clematis 20g, Angelica 30g, Baishao 30g , 20g of raw licorice, 10g of borneol, 15g of zedoary, 30g of coix seed, 40g of raw Atractylodes macrocephala, and 30g of cistanche were weighed respectively, washed, mixed together, added 3kg of ethanol with an alcohol concentration of 80%, and extracted after heating and reflux for 5 hours. Filter to get the first filtrate; Dissolve the filter residue with 80% ethanol of 1.6kg alcohol concentration again, extract after heating and reflux for 3 hours, filter to get the second filtrate; merge the first filtrate and the second filtrate, reduce Recover ethanol under pressure and concentrate until the concentration of the drug solution is 0.8g crude drug / mL, and elute with D101 macroporous adsorption resin. The volume of the resin is 5 times the volume of the con...

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Abstract

The invention provides an analgesic, prepared from the following raw materials: radix stephaniae tetrandrae, herba speranskiae tuberculatae, rhizoma corydalis, fructus evodiae, trogopterus dung, myrrh, sea cucumber, rhizoma smilacis glabrae, tabasheer, pine nodular branch, radix clematidis, Chinese angelica, radix paeoniae alba, raw liquorice root, borneol, rhizoma curcumae, semen coicis, raw rhizoma atractylodis macrocephalae and herba cistanche. The traditional Chinese medicine preparation is provided on this basis; by means of a great deal of clinical medication observation, laboratory studies and relevant safety testing, the traditional Chinese medicine preparation provided by the invention is proved to be precise and appropriate in prescription formulation and compatibility, definite in treatment effect, safe and reliable, and is clinically promoted in a dosage form of acupoint injection, thus bringing good news to patients beset by the pain of various bone diseases.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine acupoint injection analgesic for alleviating bone disease pain and a preparation method thereof. Background technique [0002] From a professional point of view, osteopathy is "osteopathology", which is one of the three major diseases of orthopedic diseases, and the other two are "osteopathology" and "muscle injury". Bone disease is also the most common disease in orthopedic diseases. It is mainly divided into: congenital bone disease, metabolic bone disease, osteonecrosis, occupational bone disease, endemic bone disease, joint degenerative bone disease, bone tumor, bone ulcer , Bone tuberculosis, bone and joint arthralgia syndrome, flaccidity syndrome, spasms and other large content. Readers here should pay attention to the fact that what we usually refer to as "bone disease" is not correct in terms of technical terms. It can ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/08A61P19/08A61P29/00A61K35/24A61K35/616A61K31/045
CPCA61K36/59A61K9/0019A61K9/08A61K31/045A61K35/24A61K35/616A61K36/15A61K36/185A61K36/232A61K36/284A61K36/328A61K36/47A61K36/484A61K36/64A61K36/65A61K36/66A61K36/71A61K36/716A61K36/754A61K36/896A61K36/899A61K36/8994A61K36/90A61K36/9066A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 孙文朋
Owner 孙文朋
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