Antialcoholism formula and preparation method thereof
A technology for formulating and relieving alcohol, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of inconvenience to carry, no repair effect on liver damage, alcohol allergy, etc., to relieve alcohol allergy, No toxic side effects, the effect of repairing liver damage
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Embodiment 1
[0032] Example 1 Preparation of Jujube Extract
[0033] Method Ⅰ: Grind dried jujube raw materials and pass through a 40-mesh sieve; according to the volume fraction of 70% ethanol solution with a solid-liquid ratio of 1:5, reflux extraction in a constant temperature water bath at 70 ℃ for 1 hour, and extract twice; filter , combined filtrates, concentrated under reduced pressure until no alcohol smell; alcohol precipitation with 3 times the volume of ethanol solution with a volume fraction of 95%, and left to stand overnight in a refrigerator at 4°C; repeated the operation 2 times, combined the alcohol-soluble parts twice, and Concentrate under pressure to obtain the extract; add appropriate amount of water to the above extract to suspend, extract with ethyl acetate, concentrate the extract solution under reduced pressure, and dry in vacuum to obtain the extract of ethyl acetate extract, which is the jujube extract.
[0034] Method Ⅱ: Grind the dried jujube raw materials and ...
Embodiment 2
[0037] Example 2 Preparation of Pueraria Radix Extract
[0038] Method Ⅰ: Grind the dried kudzu root raw material and pass it through a 40-mesh sieve; first, add disodium hydrogen phosphate-citric acid buffer solution with pH 3.6 according to the ratio of solid to liquid 1:10, and then add cellulase with a mass concentration of 0.3%, After extracting at ℃ for 50 min, the extract was filtered and concentrated under reduced pressure to obtain the extract, which was Pueraria root extract.
[0039] Method Ⅱ: Grind the dried kudzu root raw materials and pass through a 40-mesh sieve; first, add disodium hydrogen phosphate-citric acid buffer solution with a pH of 4.0 according to the ratio of solid to liquid 1:12, and then add cellulase with a mass concentration of 0.4%. After extracting at ℃ for 60 min, the extract was filtered and concentrated under reduced pressure to obtain the extract, which was Pueraria root extract.
[0040] Method Ⅲ: Grind the dried kudzu root raw materials ...
Embodiment 3
[0042] The preparation of embodiment 3 hawthorn powder
[0043] Method Ⅰ: Wash the dried hawthorn slices, dry them at 50°C, crush them, and pass through a 60-mesh sieve.
[0044] Method Ⅱ: Wash the dried hawthorn slices, dry them at 60°C, crush them, and pass through a 100-mesh sieve.
[0045] Method Ⅲ: Wash the dried hawthorn slices, dry them at 70°C, crush them, and pass them through an 80-mesh sieve.
[0046] The hawthorn powder of the present invention can be obtained by using the above three methods. Considering the influence of drying temperature on the active ingredients in hawthorn and the degree of pulverization, in order to improve its utilization rate, more preferably, the drying temperature in method II more suitable for particle size. Therefore, the hawthorn powder obtained in the selected method II is used for the preparation of the hangover prescription in Example 6.
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