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Heat-clearing granules for treating gynecology-and-obstetrics postoperative low fever

An obstetrics and gynecology, granule technology, applied in the field of heat-clearing granules for treating low fever after obstetrics and gynecology, achieves the effects of proper formulation compatibility, good clinical value, promotion prospects, and simplified medication

Inactive Publication Date: 2016-09-28
李艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] Western medicine does not have a good treatment plan for the disease, and generally adopts symptomatic treatment: if the body temperature does not exceed 38°C, no treatment is required.

Method used

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  • Heat-clearing granules for treating gynecology-and-obstetrics postoperative low fever
  • Heat-clearing granules for treating gynecology-and-obstetrics postoperative low fever
  • Heat-clearing granules for treating gynecology-and-obstetrics postoperative low fever

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preparation example Construction

[0055] The present invention also provides heat-clearing granules prepared by using the above-mentioned raw materials of traditional Chinese medicine, the preparation method of which comprises:

[0056] In the first step, the above raw materials are mixed and extracted with alcohol, followed by purification to obtain extraction powder;

[0057] In the second step, the extraction powder obtained in the first step is mixed with the carrier and auxiliary materials, and wet granulation is used to obtain granules.

[0058] In the first step, the above-mentioned raw materials are washed separately, put into an extraction container, and heated and refluxed with ethanol with an alcohol concentration of 70% to 80% for extraction. The amount of ethanol added is the sum of the mixed masses of the raw materials 6 to 8 times, the number of extractions is 2 to 4 times, and the extraction time is 1 to 2 hours each time. Collect each extract, combine, filter, and concentrate the filtrate unde...

Embodiment 1

[0061] Preparation of Example 1 Compound Qingre Granules

[0062]Raw Astragalus 30g, Ludangshen 15g, Fried Atractylodes Rhizoma 20g, Artemisia annua 15g, Digupi 15g, Turtle Shell 30g, Bupleurum 6g, Cimicifuga 6g, Patrinia 30g, Forsythia 15g, Yexiahong 15g, five Wash 25g of Zhajinlong, 12g of wine rhubarb, 9g of notoginseng, 8g of peach kernel, and 15g of curcuma, respectively, put them into an extraction container, and heat and reflux extraction with 1.8kg of ethanol with an alcohol concentration of 80%. The number of extractions is 3 times, and each extraction The time is 2 hours, collect each extract, combine, filter, the filtrate is concentrated under reduced pressure to a concentrated solution with a relative density of 1.10 at 50°C, and the macroporous adsorption resin is applied. The weight of the macroporous adsorption resin is 600g. For 40%, 60% and 80% ethanol elution, alcohol concentration is 40% ethanol volume is 2 times of macroporous adsorption resin volume, and a...

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Abstract

The invention provides heat-clearing granules for treating gynecology-and-obstetrics postoperative low fever. The heat-clearing granules contain raw milkvetch roots, codonopsis pilosula, parched white atractylodes rhizomes, artemisia annua, cortex lycii radicis, prepared turtle shells, radix bupleuri, rhizoma cimicifugae, whiteflower patrinia herb, fructus forsythiae, Phylla-gathis fordii, ipomoea cairica, wine-parched rhubarb roots, radix notoginseng, peach kernels and rhizoma zedoariae. Shown by analytical study according to traditional Chinese medicine theory, this disease is a deficiency and excess mingled symptom of deficient vital Qi and interior-retention stagnant heat. The traditional Chinese medicine preparation provided by the invention is derived from clinical practical experience, and a prescription of the traditional Chinese medicine preparation is optimized through theoretical analysis and is proper in combination and simple in medication; meanwhile, the action of the traditional Chinese medicine preparation is further proven through clinical research, and the action mechanism and safety of the traditional Chinese medicine preparation are proven through experimental research, so that the traditional Chinese medicine preparation provided by the invention has very good clinical values and popularization prospects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a heat-clearing granule for treating postoperative low fever in obstetrics and gynecology. Background technique [0002] Fever is the most common postoperative symptom. About 72% of patients have a body temperature above 37°C, and 41% have a body temperature above 38°C. Postoperative fever generally does not necessarily indicate a concomitant infection. Non-infectious fever usually occurred earlier than infectious fever (mean, 1.4 and 2.7 days postoperatively, respectively). [0003] The main causes of non-infectious fever: long operation time (2 hours), extensive tissue damage, intraoperative blood transfusion, drug allergy, hepatotoxicity caused by anesthetics (halothane or enflurane), etc. [0004] Risk factors for infectious fever include frailty, advanced age, poor nutritional status, diabetes, smoking, obesity, use of immunosuppressive drugs, or pre-e...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61P29/00A61P15/00A61K35/586
CPCA61K9/1652A61K35/586A61K36/185A61K36/233A61K36/258A61K36/28A61K36/282A61K36/284A61K36/344A61K36/481A61K36/53A61K36/634A61K36/708A61K36/71A61K36/736A61K36/80A61K36/815A61K36/87A61K36/9066A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 李艳宋相珠
Owner 李艳
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