Application of alhagi sparsifolia extract in preparation of medicine for treating irritable bowel syndrome

A technology of irritable bowel syndrome and camel thorn, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as lack

Inactive Publication Date: 2016-09-21
新疆维吾尔自治区中药民族药研究所
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Problems solved by technology

[0008] The invention provides a kind of camel thorn extract as the application of the medicine for the preparation of the treatment of irritable bowel syndrome, which overcomes the deficiencies of the above-mentioned prior art, and can effectively solve the problem that is currently lacking due to the fact that western medicine can only block one or two pathological links. Any single ideal drug can effectively treat the problem of IBS

Method used

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  • Application of alhagi sparsifolia extract in preparation of medicine for treating irritable bowel syndrome
  • Application of alhagi sparsifolia extract in preparation of medicine for treating irritable bowel syndrome
  • Application of alhagi sparsifolia extract in preparation of medicine for treating irritable bowel syndrome

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Embodiment 1

[0027] Example 1, the application of the camel thorn extract as a medicine for treating irritable bowel syndrome. The camel thorn extract can be the camel thorn extract obtained according to the prior art.

Embodiment 2

[0028]Embodiment 2, as the optimization of embodiment 1, the camel thorn extract can be obtained according to the following preparation method: the first step, get the dried camel thorn aerial part, after pulverizing, obtain camel thorn powder, use 60% to 80% ethanol Reflux extraction 2 to 3 times, the time of each ethanol reflux extraction is 1 hour to 3 hours, the consumption of ethanol during each ethanol reflux extraction is that the volume ratio of camel thorn powder and ethanol is 1:8 to 1:12, and the combined Each time the ethanol reflux extracts the extract to obtain the ethanol mixed extract; the second step is to concentrate the ethanol mixed liquid until the concentrated solution containing crude drug in the solution is 0.5g / ml to 1.5g / ml; the third step is to use petroleum ether Extract the concentrated solution for 2 to 5 times. The volume of petroleum ether used for each petroleum ether extraction is 1 to 3 times the volume of the liquid to be extracted. After the...

Embodiment 3

[0029] Embodiment 3, as the optimization of embodiment 2, the standing time in the third step is 2 hours to 6 hours, and the standing time in the fourth step is 2 hours to 6 hours. A good layering effect can be achieved by standing for 2 hours to 6 hours.

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Abstract

The invention relates to the technical field of traditional Chinese medicine and application thereof, in particular to application of an alhagi sparsifolia extract in preparation of medicine for treating an irritable bowel syndrome. The alhagi sparsifolia extract has the good treatment effect on IBS-D, particularly, the alhagi sparsifolia extract has the effects of increasing the abdominal withdrawal reflex capacity threshold value, reducing jejunal smooth muscle kinematic wave amplitude, reducing fecal water content, increasing serum K + content, reducing packed cell volume and the like and has the good effects in the aspect of inhibiting visceral hypersensitivity or relieving abnormal defecation caused by stress or irritable bowel, multiple measures are simultaneously taken in multiple pathological processes, the good treatment effect is achieved on IBS-C, IBS-D and IBS-A, a pure traditional Chinese medicine formula is adopted, and few side effects are produced.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine and its application, and relates to the application of a camel thorn extract as a medicine for treating irritable bowel syndrome. Background technique [0002] With the increase of social competition and survival pressure, the prevalence of irritable bowel syndrome (irritable bowel syndrome, IBS), a gastrointestinal disorder caused by stress, reaches 8% to 16%. IBS is a functional bowel disorder characterized by chronic or recurrent abdominal pain with altered bowel habits and lacks morphological and biochemical abnormalities. According to the defecation status of patients, it can be divided into constipation-predominant of irritable bowel syndrome (IBS-C), diarrhea-predominant of irritable bowel syndrome (IBS-D) and alternating diarrhea and constipation. Type irritable bowel syndrome (alternating-predominant of irritable bowel syndrome, IBS-A). In my country, IBS-D is the m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P1/00
CPCA61K36/48A61K2236/333A61K2236/39A61K2236/55
Inventor 魏鸿雁马晓玲夏提古丽·阿不利孜徐晓琴
Owner 新疆维吾尔自治区中药民族药研究所
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