Manual dry powder inhaler and application thereof in asthma treatment

Abstract

The invention provides a manual dry power inhaler (PP-DPI) which can treat asthma by inhaling medicines. The manual dry powder inhaler includes an air flow chamber which can inhale air from an air inlet channel, allow medicine to keep a fine power shape, form a starting part of an air channel, generate turbulent flow while the air passes through the air flow chamber to allow vibration of a medicine housing inhaled the air flow chamber, and release the medicines contained in the medicine housing; (2) a positive pressure air feeding device of a manual switch which is connected to the air flow chamber, and can trigger and push the power to flow to a contact throat through the air channel; (3) a sealing mechanism which can close the air flow chamber to form the air channel; (4) a sharp article which is arranged in the air flow chamber and can puncture the medicine housing and then release the medicines to the air channel; (5) an air discharging channel which is connected to the air flow chamber; (6) the contact throat which can form a part of the air channel, wherein the medicines can be supplied to a patient through the contact throat; (7) an optional gasket which is connected to the contact throat and facilitates inhalation of the medicines; and (8) a dosage bag having dry powder-shape medicine active ingredients capable of treating the asthma.

Description

technical field [0001] The invention provides an inhalable device and method for painlessly, accurately and directly administering ultrafine dry powder through the respiratory tract by the user in a manual positive pressure manner. At present, all known dry powder inhalation devices are breath-driven, and the power of these devices mainly comes from the flow rate of gas inhaled by the user. Specifically, the dose of dry powder inhaled by the user mainly depends on the flow rate of the gas inhaled. For long-term use For patients with this device, under normal conditions, the same inhalation device is used, and the dose of drug inhaled into the respiratory tract is also the same. The invention solves the disadvantages of the traditional inhalable drug delivery device, and is most important for the safety of the inhalable drug delivery device and the improvement of drug efficacy. Traditional Chinese medicine has been used for hundreds of years in my country and other countries, ...

AI Technical Summary

Problems solved by technology

[0021] The above-mentioned scientific studies have strongly confirmed that the combination of Chinese and Western medicines has a very good curative effect on asthma, and the use of Chinese herbal medicines alone also has a good therapeutic effect, especially that it can directly reach the lower respiratory tract through inhalation administration, which can obtain better therapeutic effects and reduce the risk of asthma. Adverse reactions, despite this, there is no report on the treatment of asthma and other diseases by inhalation administration of traditional Chinese medicine. The present invention provides positive pressure dry powder inhalation equipment to provide the possibility of inhalation administration for traditional Chinese medicine formulas and related drug formulas

[0022] Some human diseases, such as diabetes, stroke, cardiovascular disease, depression, obesity and other long-term treatment diseases, require convenient, high-efficiency and low-toxic drugs and drug delivery methods. Although some drugs currently have good curative effects, they also have serious side effects

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