Sensor based on concentration cell principle

Abstract

The invention relates to a sensor based on a concentration cell principle. The sensor is used for quantitatively detecting glucose concentration in human blood. As shown in the figures, the sensor comprises two electrodes (1) and (2), wherein the electrodes are in contact with solutions in two electrochemical pools (3) and (4), respectively; the two electrochemical pools have ion exchange through a nafion film (5); electro-active materials are contained in the two electrochemical pools (3) and (4). In the detection process, to-be-detected matter in a sample changes the concentrations of the electro-active materials in the electrochemical pools by reacting, thereby changing an electric signal (such as current or voltage) between the two electrodes; quantitative detection is performed by detecting a relation between the electric signal detected by (6) and the concentration of the to-be-detected matter. A reference electrode (such as a silver / silver chloride electrode) required by traditional electrochemical sense is not required by the sensor, the two electrodes can be made of the same material (such as graphite), the manufacturing technique is simple, and the cost is low; the influences of interfering matter in a sample on the detection can be eliminated, and thus the detection accuracy is increased.

Description

technical field [0001] The invention belongs to the field of chemical sensing, and specifically relates to a sensor based on the principle of a concentration-difference battery, which is applied to the determination of glucose content in human blood. Background technique [0002] Electrochemical sensors have the advantages of simple equipment, low cost, low power consumption, miniaturization, and quantitative detection, and have been widely used in on-site rapid detection. The most typical example is the blood glucose sensor, which currently accounts for 80% of the biosensor market. Blood glucose sensors mostly use a three-electrode system, namely working electrode, reference electrode and counter electrode. The reference electrode is often made of materials different from the working electrode and counter electrode, such as silver-silver chloride electrode. The increased electrode manufacturing steps improve the costs. In addition, due to the complex composition of blood,...

AI Technical Summary

Problems solved by technology

Blood glucose sensors mostly use a three-electrode system, namely working electrode, reference electrode and counter electrode. The reference electrode is often made of materials different from the working electrode and counter electrode, such as silver-silver chloride electrode. The increased electrode manufacturing steps improve the cost

In addition, due to the complex composition of blood, it contains a large number of substances that interfere with electrochemical detection, such as picric acid, blood cells, etc.

In order to improve the detection accuracy, it is necessary to add specific reagents or cover the electrodes with a selective film to eliminate interference, which greatly increases the cost of the sensor

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