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Data processing method based on rfMRI (resting-state functional magnetic resonance imaging) of idiopathic epilepsy

A functional magnetic resonance and primary epilepsy technology, applied in medical science, sensors, diagnostic recording/measurement, etc., can solve problems such as invasive examination and inaccurate positioning, achieve easy coordination, great application value, and avoid brain damage. The effect of activity differences

Inactive Publication Date: 2016-06-29
内蒙古医科大学附属医院
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Problems solved by technology

[0017] Aiming at the deficiencies of the prior art, the present invention provides a data processing method based on resting state functional magnetic resonance of primary epilepsy to solve problems such as invasive examination and inaccurate positioning

Method used

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  • Data processing method based on rfMRI (resting-state functional magnetic resonance imaging) of idiopathic epilepsy
  • Data processing method based on rfMRI (resting-state functional magnetic resonance imaging) of idiopathic epilepsy
  • Data processing method based on rfMRI (resting-state functional magnetic resonance imaging) of idiopathic epilepsy

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Experimental program
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Embodiment

[0030] 1. Data collection tools and objects:

[0031] In this embodiment, a 3.0TSignaHDx superconducting MR scanner (GE-SignaHDx, Milwaukee, US.) of GE Company of the United States is used, and an 8NV-Head coil is used, and the head coil is used as a transmitting and receiving coil. During the scan, the subject is awake, eyes closed, the head is fixed and the active and passive movements of the head and other parts are minimized, the subject lies quietly on the examination bed, breathes evenly, does not perform specific cognitive tasks, and is required to try as much as possible Active thinking activities are not allowed, and scanning starts after the subjects are familiar with the environment. In the case group, a 2-5 minute hyperventilation experiment was performed before scanning to increase the number of epileptiform discharges in the interval; in order to ensure the accuracy of the test, normal volunteers also performed a 2-5 minute hyperventilation experiment.

[0032] ...

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Abstract

The invention discloses a resting-state functional magnetic resonance data processing method based on primary epilepsy, which belongs to the technical field of data processing for disease detection, and comprises the following steps: S1. data collection; S2. data preprocessing; S3 .Data analysis: including ReHo data analysis, ALFF data analysis and FC data analysis, all ReHo, ALFF, FC maps are analyzed separately, and then aggregated to determine the changed brain regions. The data processing method of the present invention is extremely valuable for the exploration of multifocal epileptic lesions, avoids the difference in brain activity caused by complex task stimuli, and basically controls the experimental conditions of different subjects at the same level, and is easy to cooperate and more It is easy to draw reliable conclusions. It understands the pathogenesis of certain clinical symptoms of epileptic patients from the perspective of brain function, can help locate epileptic foci and surrounding functional areas, and guide epilepsy surgery and the resection range of epileptic foci.

Description

technical field [0001] The invention relates to the field of data processing for disease detection, in particular to a data processing method based on resting state functional magnetic resonance of primary epilepsy. Background technique [0002] Epilepsy is a common chronic nervous system disease caused by a variety of etiologies, characterized by sudden, repeated and transient central nervous system dysfunction caused by excessive discharge caused by abnormal excitability and synchronization of neuronal discharge in the brain . As of 2014, there are about 55 million epilepsy patients worldwide, and its incidence rate is higher than that of common neurological diseases such as multiple sclerosis and Parkinson's disease. At present, it is believed that epilepsy has become the second most common disease in neurological diseases after stroke, and sudden epileptic death has also attracted the attention of researchers. In real life, discrimination and ignorance of patients with...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055A61B5/00
CPCA61B5/055A61B5/4094A61B5/7207A61B5/7271
Inventor 乔鹏飞牛广明高阳刘挨师孟海霞刘晓宇
Owner 内蒙古医科大学附属医院
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