Fast-temperature-rise microfluidic chip system

Abstract

The invention relates to a fast-temperature-rise microfluidic chip system, which comprises a chip, a support frame, a two-dimensional regulating platform and an injection pump, wherein the chip comprises a substrate, a cover sheet, an electromagnetic valve, a refrigeration device and a heating device; the substrate is provided with a microfluidic passage; a constant-temperature liquid storage region, a temperature jumping region and a test region are sequentially formed in the microfluidic passage; the cover sheet covers and seals the substrate; the electromagnetic valve is communicated with the microfluidic passage; the refrigeration device is arranged in a way of being tightly attached to the constant-temperature liquid storage region of the substrate; the heating device is arranged in a way of being tightly attached to the temperature jumping region of the substrate; the test region is exposed in the irradiation of synchronous radiation light for performing test; the support frame is used for installing and fixing the chip; the two-dimensional regulating platform is used for regulating the position of the support frame and comprises a horizontal position regulating module and a vertical position regulating module; the injection pump is provided with a body and a first valve opening connected with the body; the valve opening is communicated with the microfluidic passage of the chip. The chip system provided by the invention can realize the fast temperature pumping of a solution sample, and is used for synchronous radiation reaction dynamic study.

Description

technical field [0001] The invention relates to a chip system for studying reaction kinetics, and more particularly relates to a rapid temperature-jump microfluidic chip system combined with synchrotron radiation measurement. Background technique [0002] The study of reaction kinetics is the main way to study the reaction mechanism. For the fast reaction whose half-life is less than 1s, it is impossible to study the reaction by conventional analytical techniques. Reaction kinetics has a variety of research methods, including continuous flow / stopped flow techniques, temperature jump relaxation techniques, flash photolysis techniques, and more. Among them, the temperature jump relaxation technique is a common experimental technique for studying fast reactions in solutions, that is, a temperature disturbance is applied to the equilibrium system in a short period of time, and combined with detection equipment, such as chromatography, mass spectrometry, nuclear magnetic resonan...

AI Technical Summary

Problems solved by technology

However, there are no reports on the application of microfluidic chips and synchrotron radiation to the study of temperature jump relaxation, taking advantage of the fact that the heat transfer of fluid flow in microchannels is significantly stronger than that of conventional scales.

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