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Preparation method of functional red yeast rice for preventing Alzheimer's disease

A technology of functional red yeast rice and Monascus, applied in the field of microbial culture, can solve the problem of low content of active ingredients in Alzheimer's disease, achieve the prevention and treatment of Alzheimer's disease, high content of active ingredients, and rich nutrition Effect

Active Publication Date: 2016-05-25
浙江三禾生物工程股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The monacolin, anti-inflammatory substances and antioxidant substances in the composition can be red yeast fermented product, but the preparation method of the red yeast rice fermented product adopts the common red yeast preparation process, and is not specially used for the treatment of Alzheimer’s Therefore, the content of active ingredients used in the treatment of Alzheimer's disease in the fermented red yeast rice is relatively low

Method used

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  • Preparation method of functional red yeast rice for preventing Alzheimer's disease

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Embodiment 1

[0032] A preparation method for anti-Alzheimer's disease functional red yeast rice, the steps are as follows:

[0033] A), culture medium preparation: rice is ground to make rice flour, then said rice flour is first mixed with yam powder, kudzu root powder, job's tears flour and then mixed with distilled water to make solid medium. In said solid medium, rice flour, The mass ratio of yam powder, kudzu root powder, barley powder and distilled water is 86.5:7.5:4:2:40.

[0034] Finally, the solid medium is sterilized and dispersed successively, wherein the sterilization temperature is 120-122° C., the pressure is 0.11-0.12 MPa, and the time is 40 minutes.

[0035] B), inoculation: inoculate the Monascus tumefaciens strain into the solid medium. The Monascus tufascens strain is a liquid species with a solid content of 10wt%, and the inoculum amount of the Monascus tuftscens strain per 100 g of solid medium is 15 mL.

[0036] C), cultivation: the cultivation process is divided in...

Embodiment 2

[0039] A preparation method for anti-Alzheimer's disease functional red yeast rice, the steps are as follows:

[0040] A), culture medium preparation: rice is ground to make rice flour, then said rice flour is first mixed with yam powder, kudzu root powder, job's tears flour and then mixed with distilled water to make solid medium. In said solid medium, rice flour, The mass ratio of yam powder, kudzu root powder, barley powder and distilled water is 85:8:5:2:40.

[0041] Finally, the solid medium is sterilized and dispersed successively, wherein the sterilization temperature is 120-122° C., the pressure is 0.11-0.12 MPa, and the time is 30 minutes.

[0042] B), inoculation: inoculate the Monascus tumefaciens strain into the solid medium. The Monascus tufascens species is a liquid species with a solid content of 8wt%, and the inoculum amount of the Monascus tussum species per 100g of solid medium is 12mL.

[0043] C), cultivation: the cultivation process is divided into the f...

Embodiment 3

[0046] A preparation method for anti-Alzheimer's disease functional red yeast rice, the steps are as follows:

[0047] A), culture medium preparation: rice is ground to make rice flour, then said rice flour is first mixed with yam powder, kudzu root powder, job's tears flour and then mixed with distilled water to make solid medium. In said solid medium, rice flour, The mass ratio of yam powder, kudzu root powder, barley powder and distilled water is 88:6:4:2:40.

[0048] Finally, the solid medium is sterilized and dispersed successively, wherein the sterilization temperature is 120-122° C., the pressure is 0.11-0.12 MPa, and the time is 40 minutes.

[0049] B), inoculation: inoculate the Monascus tumefaciens strain into the solid medium. The Monascus tufascens strain is a liquid species with a solid content of 10wt%, and the inoculum amount of the Monascus tuftscens strain per 100 g of solid medium is 15 mL.

[0050] Wherein, the Monascus tufascens species is domesticated: ...

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Abstract

The invention relates to the technical field of microbial culture and discloses a preparation method of functional red yeast rice for preventing Alzheimer's disease. The preparation method includes following steps: 1), preparing a culture medium: smashing rice to obtain rice flour, mixing the rice flour with yam flour, Radix puerariae powder and pearl barley flour and then distilled water to obtain a solid culture medium, and sterilizing and loosening the solid culture medium; B), inoculating: inoculating a Monascus strain; C), culturing, wherein the culturing process is divided into a first stage, a second stage and a third stage, in the first stage, culturing the culture medium at 30-35 DEG C for 3-5 days, in the second stage, culturing at 25-30 DEG C for 5-10 days, and in the third stage, culturing at 20-25 DEG C for 10-20 days; D), drying: drying the solid culture medium to obtain red yeast rice. A special process is adopted, so that the red yeast rice prepared is high in active ingredient content and suitable for preventing and treating the Alzheimer's disease.

Description

technical field [0001] The invention relates to the technical field of microorganism culture, in particular to a preparation method of anti-Alzheimer's disease functional red yeast rice. Background technique [0002] Alzheimer's disease (AD for short), also known as Alzheimer's disease, is a persistent neurological dysfunction. The most prominent early symptom is amnesia, which usually manifests as a gradual increase in short-term memory loss. As the disease progresses, the patient's language ability, spatial discrimination ability, and cognitive ability will gradually decline. Since Alzheimer's disease will cause a lot of inconvenience to the life of the elderly, and will cause a great mental and economic burden to the children, it is of great significance for the research and development of anti-Alzheimer's disease drugs . [0003] At present, there are some drugs approved for the prevention and treatment of Alzheimer's disease: acetylcholinease inhibitors (Ach-I) such a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P25/28
CPCA61K36/062A61K36/488A61K36/8945A61K36/899A61K36/8994A61K2236/11A61K2236/17A61K2300/00
Inventor 郑立忠潘荣华姜嘉善周日娟
Owner 浙江三禾生物工程股份有限公司
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