Hollow fibrous membrane reactor integrating gas distribution and enzyme catalysis and application of hollow fibrous membrane reactor

Abstract

The invention relates to a hollow fibrous membrane reactor integrating a gas distribution function and an enzyme catalysis function and an application method of the reactor. A hollow fibrous membrane is used as a gas distributor, the hollow fibrous membrane for distributing the gas and a hollow fibrous membrane of an immobilized enzyme are assembled into a same component, the bottom end of the membrane component and the bottom ends of all fibrous membranes in the component are sealed, the top end of the membrane component and the top end of the hollow fibrous membrane of the immobilized enzyme are sealed, and the top end of the hollow fibrous membrane for distributing the gas is open and is used for introducing CO2 gas; the hollow fibrous membrane reactor is applied to a formate dehydrogenase (FDH) catalytic CO2 methanoic acid synthetic system, by controlling the upstream gas rate, the number of the hollow fibrous membrane for distributing the gas and the micro-structural parameters of the membrane, the quantity and the size of bubbles, the retention time and space distribution in a solution can be adjusted, so that the gas-liquid contact time and the gas-liquid contact area can be increased, the liquid phase can be effectively disturbed, the rapid and efficient dispersion and mixing between the gas phase and the liquid phase and inside the liquid phase can be realized, and the mass transfer effect can be improved.

Description

Technical field [0001] The invention belongs to the fields of enzyme catalysis, bioreactors, and chemical processes, and relates to a hollow fiber membrane reactor with both gas distribution and enzyme catalysis functions. Background technique [0002] CO 2 It is one of the most important greenhouse gases, and its large emissions have caused the global temperature to increase. CO 2 Catalytic hydrogenation or reaction with corresponding substrates to synthesize high value-added chemicals is an important way to reuse greenhouse gases. Compared with the traditional catalytic reaction process usually carried out under high temperature and high pressure, the enzymatic catalytic method has the advantages of high efficiency, high selectivity, mild reaction conditions and no pollution to the environment, which is in line with the development trend of today's society. Take CO 2 As a raw material or one of the raw materials, it can synthesize formic acid, methanol, malic acid, isocitric a...

AI Technical Summary

Problems solved by technology

However, there are two problems in this type of reaction: on the one hand, the expensive free enzyme as a catalyst is easily soluble in the water phase and is difficult to recycle and reuse, and is easily inactivated by environmental factors or external shear forces; on the other hand, , under mild enzyme-catalyzed conditions, CO 2 The solubility in the water phase is low, and whether the gas-liquid two-phase can fully contact the mass transfer will further affect the substrate concentration in the water phase, which will have a great impact on the reaction rate and reaction equilibrium

The external hollow fiber membrane module is used as a gas distributor. After the gas is distributed, it enters the reactor through the pipeline. A considerable part of the bubbles may coalesce or even disappear. The uniformity of the gas distribution in the reactor and the disturbance effect on the solution are not as good as the built-in type. Membrane works well for generating bubbles in situ in the reactor

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