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Compound Astragalus polysaccharides injection and preparation method thereof

A technology of astragalus polysaccharides and injections, which can be used in medical formulas, medical preparations containing active ingredients, medical preparations containing active ingredients, etc., and can solve threats to human health and life safety, excessive drug residues, and animal disease resistance Weaken and other problems to achieve the effect of enhancing the body's immune response and improving the formation of antibodies

Inactive Publication Date: 2016-04-06
浙江大飞龙动物保健品股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, a large number of antibiotics are abused. The consequences of doing so will also destroy the immune system of the animal body, weakening the disease resistance of the animal, and will also lead to excessive drug residues in animal products, and the continuous emergence of drug-resistant strains, which will eventually affect human health. serious threat to health and life

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  • Compound Astragalus polysaccharides injection and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment example 1

[0024] A compound astragalus polysaccharide injection, containing per 1000ml: 10g of astragalus polysaccharide extract, 2.5g of α-mannan peptide, 0.1g of sodium bisulfite, PVP k30 10g, polyethylene glycol 100g, water for injection as solvent.

[0025] A preparation process of compound astragalus polysaccharide injection, its preparation method:

[0026] (1) Preparation of astragalus polysaccharide extract

[0027] a. Take astragalus decoction pieces, put them into a multi-functional extraction tank, add 8 times the amount of water, heat and boil twice, the first time is 2 hours, and the second time is 1.5 hours to combine the extracts, filter, and the filtrate enters the concentrator to concentrate the amount of medicinal liquid and medicinal materials The volume ratio is 2:1 (V / G).

[0028] b. Take the concentrated solution in an alcohol sink, add an equal amount of ethanol, stir evenly, refrigerate for 36 hours (0°C-10°C), filter the refrigerated solution, recover ethanol,...

Embodiment example 2

[0036] A compound astragalus polysaccharide injection, containing per 1000ml: 20g of astragalus polysaccharide extract, 5g of α-mannan peptide, 0.2g of sodium bisulfite, PVP k30 15g, polyethylene glycol 150g, water for injection as solvent.

[0037] A preparation process of compound astragalus polysaccharide injection, its preparation method:

[0038] (1) Preparation of astragalus polysaccharide extract

[0039] a. Take astragalus decoction pieces, put them into a multi-functional extraction tank, add 8 times the amount of water, heat and boil twice, the first time is 2 hours, and the second time is 1.5 hours to combine the extracts, filter, and the filtrate enters the concentrator to concentrate the amount of medicinal liquid and medicinal materials The volume ratio is 2:1 (V / G).

[0040]b. Take the concentrated solution in an alcohol sink, add an equal amount of ethanol, stir evenly, refrigerate for 36 hours (0°C-10°C), filter the refrigerated solution, recover ethanol, an...

Embodiment example 3

[0048] A compound astragalus polysaccharide injection, containing per 1000ml: 50g of astragalus polysaccharide extract, 10g of α-mannan peptide, 0.5g of sodium bisulfite, PVP k30 20g, polyethylene glycol 200g, water for injection as solvent.

[0049] A preparation process of compound astragalus polysaccharide injection, its preparation method:

[0050] (1) Preparation of astragalus polysaccharide extract

[0051] a. Take astragalus decoction pieces, put them into a multi-functional extraction tank, add 8 times the amount of water, heat and boil twice, the first time is 2 hours, and the second time is 1.5 hours to combine the extracts, filter, and the filtrate enters the concentrator to concentrate the amount of medicinal liquid and medicinal materials The volume ratio is 2:1 (V / G).

[0052] b. Take the concentrated solution in an alcohol sink, add an equal amount of ethanol, stir evenly, refrigerate for 36 hours (0°C-10°C), filter the refrigerated solution, recover ethanol, ...

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Abstract

The invention relates to a compound Astragalus polysaccharides injection and a preparation method thereof and belongs to the technical field of veterinary preparations. The injection per 1000 ml contains: 10-50 g of Astragalus polysaccharides extract, 2.5-10 g of alpha-mannatide, 0.1-0.5 g of sodium hydrogen sulfite, 10-20 g of PVPk30 and 100-200 g of polyethylene glycol. The injection has the advantages that the injection is given improved solution viscosity, reduced pharmaceutical spread speed and prolonged acting time by the addition of water-soluble polymer materials PVPk30 and polyethylene glycol, and the injection is taken only once a day; as in the injection prepared by the invention, bioactivity of polysaccharides is made full use by using two natural polysaccharides of different origins, Astragalus polysaccharides and alpha-mannatide, immunity enhancement is effectively exerted, and antibody formation improvement and body immunity response enhancement are clinically achieved.

Description

technical field [0001] The invention belongs to the technical field of veterinary preparations, and in particular relates to a compound astragalus polysaccharide injection and a preparation method thereof. Background technique [0002] In recent years, with the improvement of people's living standards, my country's animal husbandry has developed rapidly, but at the same time as the development, due to the continuous expansion of the breeding scale and the increase of the breeding density, the living environment of animals is getting worse and worse, and animal diseases occur frequently. , especially the incidence of some immunosuppressive diseases showed a linear upward trend. According to the analysis of industry insiders, the current occurrence of animal diseases in my country is diversified and complicated. The root cause is that the animal body is in a state of immunosuppression for a long time, which greatly weakens the body's immunity and resistance, and the vaccine imm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K38/16A61K47/32A61K47/34A61P37/04A61K31/715
CPCA61K9/08A61K9/0019A61K31/715A61K35/744A61K36/481A61K38/16A61K47/32A61K47/34A61K2300/00
Inventor 沈建军舒鑫标柳雪雁彭俊平宋占学施伟领胡永明
Owner 浙江大飞龙动物保健品股份有限公司
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