Traditional Chinese medicine preparation for treating diabetic peripheral neuropathic pain and preparation method thereof

A traditional Chinese medicine preparation and diabetes technology, applied in the field of traditional Chinese medicine, can solve the problems of ineffective treatment effect of diabetic peripheral neuralgia, increase the metabolic burden of patients, and easy recurrence of the disease, so as to ensure physical and mental health, take medicine conveniently, and avoid repeated attacks. Effect

Inactive Publication Date: 2016-03-23
XUZHOU MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Neuropathic pain has a wide range of clinical causes, diverse symptoms, and complex pathological mechanisms. Conventional analgesics such as opioids, strong narcotic analgesics, and non-steroidal anti-inflammatory drugs have no obvious curative effect on it, so it has become a difficult point in clinical treatment. In addition, some conventional drugs for the treatment of neuropathic pain, such as antidepressants, anticonvulsants and antiepileptic drugs, have no significant therapeutic effect on diabetic peripheral neuralgia, and the adverse reactions of these drugs are large
[0003] At

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] A preparation method of a Chinese medicine preparation for the treatment of diabetic peripheral neuralgia, the preparation method consists of the following steps:

[0048] (1) Raw material preparation: select tender cinnamon twigs in April, cut them into sections when they are fresh, and dry them in the air. Weigh 0.5 parts of dried cinnamon twigs; weigh 0.2 parts of Angelica dahurica; 0.35 parts of dried cocklebur; choose the washed and dried cocklebur, fry it, grind it through a 200-mesh sieve, weigh 1.3 parts of cocklebur powder; choose fresh peach branches with a diameter of 0.35-0.8cm, wash the surface Finally, blow dry under warm air at 35-45°C, weigh 1.15 parts of dried peach branches; weigh 0.55 parts of drynaria and 2 parts of walnut leaves; take clean pearls, crush, grind, and finely pass through a 400-mesh sieve , weighed 0.05 part of pearl powder; respectively weighed 0.35 part of Shouwu vine, 0.4 part of jujube seed, 0.45 part of litchi core, and 0.15 part ...

Embodiment 2

[0058] A preparation method of a Chinese medicine preparation for the treatment of diabetic peripheral neuralgia, the preparation method consists of the following steps:

[0059] (1) Raw material preparation: select tender cinnamon twigs in April, cut them into sections when they are fresh, and dry them in the air. Weigh 0.5 parts of dried cinnamon twigs; weigh 0.2 parts of Angelica dahurica; 0.35 parts of dried cocklebur; choose the washed and dried cocklebur, fry it, grind it through a 200-mesh sieve, weigh 1.3 parts of cocklebur powder; choose fresh peach branches with a diameter of 0.35-0.8cm, wash the surface Finally, blow dry under warm air at 35-45°C, weigh 1.15 parts of dried peach branches; weigh 0.55 parts of drynaria and 2 parts of walnut leaves; take clean pearls, crush, grind, and finely pass through a 400-mesh sieve , weighed 0.05 part of pearl powder; respectively weighed 0.35 part of Shouwu vine, 0.4 part of jujube seed, 0.45 part of litchi core, and 0.15 part ...

Embodiment 3

[0069] 1. The clinical data of Chinese medicine preparation of the present invention treating diabetic peripheral neuralgia:

[0070]Diabetic peripheral neuralgia, as a complication of diabetes, is a type of neuropathy with pain as the main manifestation, and belongs to neuropathic pain. The early symptoms of diabetic peripheral neuralgia are mainly sensory disturbance, mainly including numbness, ants walking, insect crawling, fever, electric shock and other symptoms. It often goes up to the knee from the distal toe, and the patient feels like wearing socks and gloves, and often presents a "sock cover" and "glove" distribution. As the course of the disease progresses, the main clinical manifestations are numbness, pain, hyperalgesia, allodynia, muscle weakness, burning, acupuncture, etc. in the distal extremities. In severe cases, it will develop into diabetic foot ulcers and even require amputation.

[0071] At present, there are 92.4 million diabetic patients in my country...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating diabetic peripheral neuropathic pain and belongs to the technical field of traditional Chinese medicine. The preparation is prepared from, by weight, 0.5 part of cassia twigs, 0.2 part of radix angelicae, 0.35 part of Chinese mosla herb, 1.3 parts of fructus xanthii, 1.15 parts of peach twigs, 0.55 part of drynaria total flavonoids, 2 parts of schefflera kwangsiensis, 0.35 part of multiflower knotweed vines, 0.05 part of pearl powder, 0.4 part of semen ziziphi spinosae, 1.2 parts of fructus choerospondiatis, 1.25 parts of semen platycladi, 0.3 part of cinnamon, 0.25 part of clove, 0.015 part of fennel, 0.035 part of illicium verum, 0.5 part of prunus mume, 0.45 part of semen litchi, 0.15 part of tangerine seeds and 3 parts of auxiliary materials. The invention further provides a preparation method of the preparation. The traditional Chinese medicine is stable and controllable, and has a remarkable effect on treatment of peripheral neuropathic pain symptoms of diabetic patients. Clinical application verifies that symptom treatment side effects are few, the preparation is soft, harmless and free of addiction, obvious adverse effects do not occur, and the clinical total effective rate of the Chinese medicine reaches 86.7%.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating diabetic peripheral neuralgia and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Diabetes is an endocrine and metabolic disease characterized by hyperglycemia. It is a chronic, multiple common disease, often accompanied by complications, and its incidence is increasing year by year. big disease. Complications of diabetes bring infinite pain to people, such as diabetic peripheral neuropathic pain, which is a kind of neuropathic pain, and is one of the common complications of diabetes. Neuropathic pain has a wide range of clinical causes, diverse symptoms, and complex pathological mechanisms. Conventional analgesics such as opioids, strong narcotic analgesics, and non-steroidal anti-inflammatory drugs have no obvious curative effect on ...

Claims

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Application Information

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IPC IPC(8): A61K36/77A61P3/10A61P25/02A61K35/618
CPCA61K36/54A61K9/146A61K35/618A61K36/126A61K36/14A61K36/185A61K36/22A61K36/23A61K36/232A61K36/28A61K36/53A61K36/57A61K36/61A61K36/704A61K36/725A61K36/736A61K36/752A61K36/77A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 苗蓓程伟殷琴
Owner XUZHOU MEDICAL COLLEGE
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