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Application of elephantopus plant extract in preparation of fishery drugs having antibacterial effect

A technology of plant extracts and antibacterial effects, applied in antibacterial drugs, plant/algae/fungus/moss components, plant raw materials, etc., can solve side effects and other problems, achieve good antibacterial effect, easy large-scale production, and extensive resources Effect

Active Publication Date: 2016-03-16
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of antibiotics will have adverse effects on both aquatic ecosystems and fish quality

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Dry 1000g of the whole herb of Echinacea, reflux extraction with 5000mL of 70% ethanol for 3 times, each time for 2 hours, combine the extracts, recover under reduced pressure to obtain 154g of dry extract;

[0033] Weigh 2000g of macroporous adsorption resin (D101), add 4000mL of distilled water, stir evenly, remove resin monomer or debris by water flotation, and then place it at room temperature for 24h; after the resin is fully swollen, drain the resin, and then use volume The column is wet-packed with 95% ethanol; then the column is washed with 95% ethanol by volume until the effluent is mixed with water (1:5) and does not become turbid, and then fully rinsed with distilled water until the effluent is free of ethanol. Taste; use 2% NaOH by mass to pass through the resin column, soak for 2-4 hours, then wash with distilled water until neutral, and set aside;

[0034] Add 3000mL of water to dissolve the dried extract of Radix Echinacea, add the sample to the above-men...

Embodiment 2

[0037] Dried 1000g of the whole herb of Radix Dipinscens, reflux extracted with 5000mL of 70% ethanol for 3 times, each time for 2 hours, combined the extracts, recovered under reduced pressure to obtain 137g of dry extract;

[0038] Weigh 2000g of macroporous adsorption resin (D101), add 4000mL of distilled water, stir evenly, remove resin monomer or debris by water flotation, and then place it at room temperature for 24h; after the resin is fully swollen, drain the resin, and then use volume The column is wet-packed with 95% ethanol; then the column is washed with 95% ethanol by volume until the effluent is mixed with water (1:5) and does not become turbid, and then fully rinsed with distilled water until the effluent is free of ethanol. Taste; use 2% NaOH by mass to pass through the resin column, soak for 2-4 hours, then wash with distilled water until neutral, and set aside;

[0039] Add 3000mL of water to dissolve the dried extract of Rhododendron chinensis, add the sampl...

Embodiment 3

[0042] Dried 1000g of the whole herb of Echinacea, reflux extraction with 5000mL of 70% ethanol for 3 times, each time for 2 hours, combined the extracts, recovered under reduced pressure to obtain 166g of dry extract;

[0043]Weigh 2000g of macroporous adsorption resin (D101), add 4000mL of distilled water, stir evenly, remove resin monomer or debris by water flotation, and then place it at room temperature for 24h; after the resin is fully swollen, drain the resin, and then use volume The column is wet-packed with 95% ethanol; then the column is washed with 95% ethanol by volume until the effluent is mixed with water (1:5) and does not become turbid, and then fully rinsed with distilled water until the effluent is free of ethanol. Taste: use 2% NaOH by mass to pass through the resin column, soak for 2-4 hours, then wash with distilled water until neutral, and set aside;

[0044] Add 3000mL of water to dissolve the dried extract of Radix Echinacea, add the sample to the above...

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Abstract

The invention relates to the technical field of fishery drugs, and in particular, relates to an application of an elephantopus plant extract in preparation of fishery drugs having an antibacterial effect. An elephantopus plant is elephantopus mollis or elephantopus scaber. The elephantopus plant extract has good antibacterial effect, can be used for treating fish enteritis, red skin disease or gill-rot disease caused by bacteria infection; and in addition, the elephantopus plant is wide in resources and cheap, and the extract preparation process is simple and is prone to large-scale production.

Description

technical field [0001] The invention relates to the technical field of fishery medicines, in particular to the application of a plant extract of the genus Echinacea in the preparation of fishery medicines with antibacterial effects. Background technique [0002] Fish diseases have become a bottleneck for the sustainable development of aquaculture, such as in the Pearl River Delta region. Various antibiotics have been widely used. However, the use of antibiotics will have adverse effects on both aquatic ecosystems and fish quality. [0003] Traditional Chinese medicine can prevent and treat diseases, promote animal growth, and will not produce drug residues that are harmful to human health. Traditional Chinese medicine in my country has gradually been valued by the majority of veterinary drug manufacturers. Therefore, using traditional Chinese medicines as raw materials to develop fishery medicines containing natural ingredients to replace traditional chemical fishery medic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P31/04
CPCA61K36/28A61K2236/333A61K2236/39A61K2236/55
Inventor 李药兰叶文才王国才李满妹王英
Owner JINAN UNIVERSITY
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