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Medicine encapsulation rubber plug

A technology for medicines and rubber stoppers, applied in the field of medicine encapsulation rubber stoppers, can solve the problems of poor safety in use, difficult to prepare medical rubber products, complicated process, etc., and achieve excellent mechanical properties, novel formula design, and high chemical stability. Effect

Inactive Publication Date: 2016-02-10
ANHUI ZHONGMA RUBBER & PLASTIC PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Under the conditions of high temperature and high pressure, traditional medical rubber products tend to produce exudates and volatiles that pollute the human body and pharmaceuticals in their vulcanization system, making it difficult to prepare medical rubber products that meet the highest quality standards for pharmaceuticals
Existing medical rubber products and preparation methods thereof have complicated process, poor product environmental protection, weak use safety, and low service life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A drug packaging rubber stopper, mainly composed of auxiliary glue, epoxy resin glue and mixed liquid,

[0025] The auxiliary glue includes: 70 parts of deionized water, 10 parts of ethylene vinyl acetate copolymer, 8 parts of chitosan, 5 parts of hydroxypropyl methylcellulose, 2 parts of propolis, 1 part of kaolin, 0.8 parts of titanium dioxide, nano 2 parts of diatomite, 0.5 part of white oil, 0.5 part of sorbic acid;

[0026] Epoxy resin glue includes: epoxy resin 100 parts, epichlorohydrin: 10 parts, talc powder: 16 parts, quartz powder: 21 parts, mica powder: 20 parts, titanium dioxide: 15 parts, curing agent: 5 parts, liquid Low molecular weight polyamide: 30 parts, m-cresol curing accelerator: 1 part, silane coupling agent: 1 part;

[0027] The mixture includes: 5 parts of ginseng, 5 parts of Atractylodes macrocephala, 5 parts of raw grain buds, 50 parts of water, 5 parts of burnt hawthorn, 5 parts of Divine Comedy, 5 parts of Polygonatum odoratum, 9 parts of Ti...

Embodiment 2

[0029] A drug packaging rubber stopper, mainly composed of auxiliary glue, epoxy resin glue and mixed liquid,

[0030] The auxiliary glue includes: 90 parts of deionized water, 15 parts of ethylene vinyl acetate copolymer, 12 parts of chitosan, 8 parts of hydroxypropyl methylcellulose, 5 parts of propolis, 5 parts of kaolin, 3 parts of titanium dioxide, nano 3 parts of diatomite, 2 parts of white oil, 1.5 parts of sorbic acid;

[0031] Epoxy resin glue includes: epoxy resin 150 parts, epichlorohydrin: 13 parts, talc powder: 19 parts, quartz powder: 25 parts, mica powder: 25 parts, titanium dioxide: 20 parts, curing agent: 10 parts, liquid Low molecular weight polyamide: 35 parts, m-cresol curing accelerator: 2 parts, silane coupling agent: 2 parts;

[0032] The mixed solution includes: 10 parts of ginseng, 10 parts of Atractylodes macrocephala, 10 parts of raw grain buds, 60 parts of water, 10 parts of burnt hawthorn, 10 parts of Divine Comedy, 7 parts of Polygonatum odoratum...

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Abstract

A medicine encapsulation rubber plug mainly is prepared by mixing auxiliary rubber, an epoxy resin adhesive and a mixed solution. A preparation method for the medicine encapsulation rubber plug comprises the following steps: separately adding the mixed solution to the auxiliary rubber and the epoxy resin adhesive according to the ratio of 1: 1.36, stirring for 10 minutes, taking 20% of mixed rubber comprising the epoxy resin adhesive and the mixed solution to be mixed with the auxiliary rubber, stirring, adding the remaining 80% of the mixed rubber comprising the epoxy resin adhesive and the mixed solution after 3 minutes, and continuously stirring for 2 minutes to obtain a colloid; cooling the colloid in air at the temperature of 15 DEG C for 1 day, and slicing to obtain the medicine encapsulation rubber plug. The medicine encapsulation rubber plug has the benefits that the formula and the design are novel, the raw materials are easy to obtain, and a rubber product prepared according to the formula is higher in chemical stability, free of irritation, high in safety, heat-proof and ageing-resistant, has an excellent mechanical property, and can be made into medicine encapsulation rubber plugs with different specifications.

Description

Technical field: [0001] The invention relates to the technical field of medical rubber production, in particular to a medicine packaging rubber stopper. Background technique: [0002] With the development of society, there are more and more types of rubber products used in the medical and health field, such as rubber stoppers for various pharmaceutical bottles, pistons for sterile syringes, sealing rubber seals for injections, hoses, catheters, medical air cushions, sterilization Rubber medical gloves, baby pacifiers, blood transfusion tubes, etc. Ideal medical rubber products not only need to have good physical properties, but also must be non-toxic and chemically inert. In particular, rubber products in the body should have the characteristics of not causing disease, not damaging adjacent tissues, not causing allergies, and having good aging properties. [0003] Under the conditions of high temperature and high pressure, the vulcanization system of traditional medical rub...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L63/00C08L23/08C08L5/08C08L1/28C08L97/02C08K13/02C08K3/34C08K3/22C08K3/36
Inventor 张艳
Owner ANHUI ZHONGMA RUBBER & PLASTIC PROD
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