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Chinese-western medicine compound preparation used for treating cervical leukoplakia and preparation method thereof

A compound preparation, Chinese and Western medicine technology, applied in the field of medicine, can solve problems such as risk, increased secretion, and heavy bleeding, and achieve the effect of good clinical application value

Inactive Publication Date: 2016-02-03
张雪梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the treatment methods of Western medicine are mainly cervical cryotherapy or cervical conization. Cervical cryotherapy uses low temperature technology to generate ultra-low temperature, resulting in freezing of lesion tissue, secondary necrosis, and shedding to achieve the purpose of treatment. If the cryotherapy is used properly, the freezing depth can reach When it reaches 5-6mm, the tissue in the lesion area will be necrotic and fall off, and the healthy epithelium will re-grow. However, this operation is risky, and it is not suitable for patients with heart disease, asthma, epilepsy, etc., and there are certain side effects, such as bleeding and increased secretions. Wait
Cervical conization is suitable for long-term cure or severe cervical erosion. The effect is reliable, and it can be used for pathological serial sections to more accurately find out whether there is early cervical cancer. However, the operation may cause more bleeding and postoperative infection is prone to occur
[0006] TCM treatment of this disease emphasizes soothing the liver and invigorating the spleen, removing dampness and clearing away heat. In addition to internal medicine, it also needs to be combined with external medicine for anti-inflammation, removing putrefaction and promoting muscle growth, so the treatment is more troublesome

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A Chinese and Western medicine compound preparation for treating cervical leukoplakia is mainly prepared from the main ingredients and auxiliary ingredients in the following weight ratios:

[0035] Main ingredients: 60 parts of Artemisia annua branch, 50 parts of wild mat grass root, 45 parts of jiexianghua, 40 parts of tortoise, 30 parts of xiangyuanzi, 30 parts of mulberry root, 30 parts of hollow flower, 2 parts of non-steroidal anti-inflammatory drugs;

[0036] Accessories: 15 parts of mandarin leaves, 15 parts of moss water flower, 10 parts of Geshan Xiao, 10 parts of weeping grass, 10 parts of dandelion, 5 parts of banyan beard, 5 parts of Ligustrum lucidum, 3 parts of stinky cabbage, 3 parts of propylene glycol alginate , 2 parts of chitosan-dextran complex.

[0037] The chitosan-dextran complex is stirred and mixed by chitosan and dextran at a temperature of 25° C. at a speed of 10 r / min, wherein the weight ratio of chitosan is 10%, the chitosan-dextran complex...

Embodiment 2

[0047] A Chinese and Western medicine compound preparation for treating cervical leukoplakia is mainly prepared from the main ingredients and auxiliary ingredients in the following weight ratios:

[0048] Main ingredients: 70 parts of Artemisia annua branch, 60 parts of wild mat grass root, 55 parts of jiexianghua, 50 parts of tortoise, 40 parts of xiangyuanzi, 40 parts of mulberry root, 35 parts of hollow flower, 2.5 parts of non-steroidal anti-inflammatory drugs;

[0049] Excipients: 16 parts of mandarin leaves, 16 parts of moss water flower, 12 parts of Geshanxiao, 12 parts of weeping grass, 11 parts of dandelion, 7 parts of banyan beard, 6 parts of Ligustrum lucidum, 4 parts of stinky cabbage, 3.5 parts of propylene glycol alginate , 3 parts of chitosan-dextran complex.

[0050] The chitosan-dextran complex is stirred and mixed by chitosan and dextran at a temperature of 26° C. at a speed of 10 r / min, wherein the weight ratio of chitosan is 20%, the chitosan-dextran compl...

Embodiment 3

[0060] A Chinese and Western medicine compound preparation for treating cervical leukoplakia is mainly prepared from the main ingredients and auxiliary ingredients in the following weight ratios:

[0061] Main ingredients: 80 parts of Artemisia annua branch, 70 parts of wild mat grass root, 65 parts of Jiexiang flower, 60 parts of tortoise, 60 parts of Xiangyuanzi, 45 parts of mulberry root, 37.5 parts of hollow flower, 2.75 parts of non-steroidal anti-inflammatory drugs;

[0062] Excipients: 17.5 parts of mandarin leaves, 17.5 parts of moss water flower, 15 parts of Geshanxiao, 15 parts of weeping grass, 12.5 parts of dandelion, 10 parts of ficus ficus, 7.5 parts of Ligustrum lucidum, 4.5 parts of stinky cabbage, 4 parts of propylene glycol alginate , 3.5 parts of chitosan-dextran complex.

[0063] The chitosan-dextran complex is stirred and mixed by chitosan and dextran at a temperature of 27.5° C. at a speed of 10 r / min, wherein the weight ratio of chitosan is 50%, the chi...

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PUM

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Abstract

The invention discloses a Chinese-western medicine compound preparation used for treating cervical leukoplakia and a preparation method thereof. The Chinese-western medicine compound preparation used for treating cervical leukoplakia is mainly prepared from the following main materials and accessory materials: the main materials comprise all-grass of purple cyathocline, root of Juncus setchuensis Buch., Flos Edgeworthlae, Clerodendron petasites, medicinal citron seed, root of clammy hopseedbush, Maesa perlarius and a non-steroid anti-inflammatory agent; and the accessory materials comprise stringy stonecrop herb, dandelion, glossy privet fruit, smallfruit fig aerial root, Pilea japonica, Cynanchum wilfordii, chachi citrus leaf, Cleome viscosa L., propylene glycol alginate and a chitosan-glucan compound. Effective concomponents in traditional Chinese medicines are extracted for preparation of a suppository. According to the invention, traditional Chinese medicinal materials are reasonably selected and combined according to the theory of traditional Chinese medicine and are cooperatively used with western medicinal components; the prepared compound preparation is delivered in the vagina, can locally exert antibacterial, anti-inflammatory, necrotic tissue-removing and granulation-promoting effects and is capable of entering blood circulation under the action of absorption by the vaginal canal to exert liver-coursing, spleen-invigorating, dampness-eliminating, heat-clearing, blood-nourishing and yin-nourishing effects; and the compound preparation comprehensively performs drug effect to realize comprehensive treatment of cervical leukoplakia, and is fast, effective, safe and free of side-effect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Chinese and western medicine compound preparation for treating cervical leukoplakia and a preparation method thereof. Background technique [0002] Cervical leukoplakia (Leucoplasia of the cervix) refers to a gray-white opaque plaque-like lesion that appears in the cervix and vagina. Most scholars believe that white spots seen clinically only indicate different degrees of epithelial hyperplasia. With the in-depth study of cervical precancerous lesions and early cancer and the wide application of colposcopy, this disease has gradually attracted attention. [0003] The factors that cause cervical leukoplakia mainly include endocrine disorders or chronic cervical inflammation, local stimulation of Trichomonas vaginalis, and some other factors such as atypical hyperplasia, carcinoma in situ or early invasive carcinoma, etc., which may also be related to carcinogenic factors of ce...

Claims

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Application Information

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IPC IPC(8): A61K45/00A61K36/88A61K9/02A61K47/36A61P15/00A61P15/02
Inventor 张雪梅游莲莲曹金丽
Owner 张雪梅
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