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A kind of preparation method of animal depilation therapeutic agent and medicinal use thereof

A therapeutic agent and animal technology, which is applied to the preparation of microcapsule oral dosage forms of animal hair removal therapeutic agents, and the preparation of animal hair removal therapeutic agents, can solve the problems of uneven mixing, animal anemia, unreasonable dietary formula, etc. The effect of reducing the variety and simplifying the production process

Active Publication Date: 2018-04-17
SICHUAN AGRI UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most animals are kept in captivity, and unreasonable dietary formulas are prone to cause animal anemia due to the lack of copper and zinc trace elements, which seriously affects the economic benefits of animal breeding
Trace element feed additives are likely to cause uneven mixing and cause animal poisoning and environmental pollution

Method used

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  • A kind of preparation method of animal depilation therapeutic agent and medicinal use thereof
  • A kind of preparation method of animal depilation therapeutic agent and medicinal use thereof
  • A kind of preparation method of animal depilation therapeutic agent and medicinal use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A. Method

[0030] 1. Select 20 mice with a body weight of (30±5) g, half male and half male, formulate mouse feed according to the relevant regulations on animal feed in my country, and establish a depilatory model. 10 mice with severe hair loss symptoms were selected as test mice and divided into control group and test group. The test group was fed with copper-zinc compound microcapsules at a dose of 0.1g / kg, and was administered once every other day.

[0031] 2. Compare the hair loss of the mice before and after 45 days of feeding the microcapsules.

[0032] B. Results

[0033] 1. After the hair loss model mice were fed with copper-zinc composite microcapsules for 45 days, the hair loss of the mice in the test group was significantly better than that of the mice in the control group. The results are shown in figure 1 .

[0034] 2. Summary

[0035] From figure 1 (a)(b) It can be seen that the mouse model of depilation is successful. From figure 1 (c)(d) It can...

Embodiment 2

[0037] A. Method

[0038] 1. Select 20 mice with a body weight of (30±5) g, half male and half male, formulate mouse feed according to the relevant regulations on animal feed in my country, and establish a depilatory model. 10 mice with severe hair loss symptoms were selected as test mice and divided into control group and test group. The test group was fed with copper-zinc composite microcapsules at a dose of 0.2g / kg, and gavaged once every other day.

[0039] 2. Compare the hair loss of the mice before and after 45 days of feeding the microcapsules.

[0040] B. Results

[0041] 1. After the hair loss model mice were fed with copper-zinc composite microcapsules for 45 days, the hair loss of the mice in the test group was significantly better than that of the mice in the control group. The results are shown in figure 2 .

[0042] 2. Summary

[0043] From figure 2 (a)(b) It can be seen that the mouse model of depilation is successful. It can be seen from Figure (c) (d)...

Embodiment 3

[0045] A. Method

[0046] Twenty depilated mice were divided into a test group and a control group, 10 in each group. The test group was fed with copper-zinc composite microcapsules 0.15g / kg body weight, and the control group was fed with normal saline 0.15ml / kg body weight, every other day, for a total of 4 times. After 15 days of administration, the condition of depilated mice was observed.

[0047] B. Results

[0048]

[0049] C. Summary

[0050] The depilated mice fed with copper-zinc composite microcapsules have increased appetite, better mental state than the control group, and bright coat, indicating that this preparation can enhance the immunity of mice, promote metabolism, and improve animal health. The effect of hair.

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Abstract

The invention discloses a preparation method of an animal hair removal therapeutic agent and its medicinal use. Zinc gluconate and copper sulfate are used as main active components to form microcapsules formed by fully heating, stirring and dissolving in an oil / water solvent, and the main components are obtained. The composition is zinc gluconate, copper sulfate as the core of the capsule, and acrylic resin as the capsule material of copper-zinc composite microcapsules. The copper-zinc composite microcapsule of the invention overcomes the disadvantages of animal poisoning and environmental pollution caused by uneven mixing that is easily caused by conventional feed additives. Balanced supply, safe and effective, easy to use, non-toxic and side effects, and can slowly release microcapsules supplementing copper and zinc trace elements at the same time, which can significantly increase its coat content. An appropriate amount of copper-zinc composite microcapsules can treat animal alopecia, improve its immunity, and promote metabolism.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and relates to a preparation method of an animal hair removal treatment agent, in particular to a preparation method of a microcapsule oral dosage form of the animal hair removal treatment agent. Background technique [0002] Trace elements are an important material basis for the survival and healthy growth of animal organisms. Among them, the main functions of copper and zinc in the body are: copper is an important component of proteins and enzymes in the body, many key enzymes require the participation and activation of copper, and have an effect on the metabolic process of the body. It affects the development of hair, skin, bones, and brain, as well as the function of the heart, liver, central nervous system, and immune system, among others. Zinc can promote the growth and tissue regeneration of the body, because zinc is an essential component of DNA polymerase that regulates gene...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/34A61K9/50A61P17/14A61K31/315
Inventor 胡延春汤承岳华乔艳许锐光吴冬梅蔡海王远微
Owner SICHUAN AGRI UNIV
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