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Immunological preparation for preventing and treating porcine reproductive and respiratory syndromes

A technology for respiratory syndrome and immune preparations, applied in the field of immunity, can solve the problems of lack of protection, inability to stimulate cellular immunity, and immune response taking a long time.

Inactive Publication Date: 2016-01-06
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, the main problems of porcine reproductive and respiratory syndrome vaccines are: first, it takes a long time for the vaccine to produce an immune response; second, porcine reproductive and respiratory syndrome vaccines do not have complete protection, especially inactivated vaccines cannot Stimulate cellular immunity; third, attenuated porcine reproductive and respiratory syndrome vaccine can exist in the body tissues of immunized pigs for several weeks and spread from vaccinated pigs to susceptible pigs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0041] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine immune preparation, specifically:

[0042] Grind each raw drug composition to 20-40 mesh respectively, mix together according to the above weight parts, then put it into an ethanol solution whose volume is 6-12 times of the amount of medicinal materials and whose volume concentration is 70%-95%. Reflux extraction method, extraction 2 to 4 times, each extraction time is 1.5 to 2.5 hours, the extraction temperature is 65 ° C to 85 ° C, the extraction solution is mixed, filtered, and the filtrate is collected, concentrated on a rotary evaporator, and the ethanol solvent is removed , dried and pulverized to obtain immune preparations.

[0043] The present invention also provides a feed for preventing and treating porcine reproductive and respiratory syndrome. amino acid and methionine.

[0044] Further preferably, the feed is prepared only from the above-mentioned ...

Embodiment 1

[0055] Embodiment 1 Immunization preparation 1

[0056] 25g Epimedium, 40g Polygonatum, 30g Gorgon, 15g Ephedra, 20g Goose Bubivora, 25g Shayuanzi, 35g Forsythia, 30g Codonopsis 30g, 20g Water Gardenia, 25g Chinese Yam, 20g Cortex Moutan, 35g Acanthopanax, white Curculigo 15g, Twister 15g, Clover 20g, Maweilian 15g, Sangjisheng 30g, Rhubarb 20g, Nansha ginseng 25g and Yizhi 15g were respectively crushed to 40 mesh, mixed together, and then put into a volume of In the ethanol solution whose volume concentration is 90% and 10 times of the amount of medicinal materials, adopt the reflux extraction method, extract 3 times, each extraction time is 2h, and the extraction temperature is 75°C, the extraction solution is mixed, filtered, and the filtrate is collected and placed in Concentrate on a rotary evaporator, remove the ethanol solvent, dry, and pulverize to obtain immune preparations.

Embodiment 2

[0057] Embodiment 2 immune preparation 2

[0058] 23g Epimedium, 38g Polygonatum, 28g Gorgon, 13g Ephedra, 18g Goose Bubiograss, 23g Shayuanzi, 33g Forsythia, 28g Codonopsis, 18g Water Gardenia, 23g Chinese yam, 18g Cortex Moutan, 33g Acanthopanax, white Curculigo 13g, Twister 13g, Clover 18g, Maweilian 13g, Sangjisheng 28g, Rhubarb 18g, Nansha ginseng 23g and Yizhi 13g were respectively crushed to 40 meshes, mixed together, and then put into a volume of In the ethanol solution whose volume concentration is 90% and 10 times of the amount of medicinal materials, adopt the reflux extraction method, extract 3 times, each extraction time is 2h, and the extraction temperature is 75°C, the extraction solution is mixed, filtered, and the filtrate is collected and placed in Concentrate on a rotary evaporator, remove the ethanol solvent, dry, and pulverize to obtain immune preparations.

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PUM

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Abstract

The invention provides an immunological preparation for preventing and treating porcine reproductive and respiratory syndromes. The immunological preparation comprises epimedium, sealwort, Gorgon fruits, ephedra herbs, centipeda minima, flatstem milkvetch seeds, forsythia, companumoea roots, cape jasmines, yams, tree peony bark, acanthopanax roots, curculigo orchioides, jasminum elongatum, clovers, meadowrue roots and rhizomes, mistletoes, rheum franzenbachii, adenophora tetraphylla and alpinia oxyphylla. The immunological preparation has the advantages that cellular immunity and humoral immunity of organisms can be enhanced through the organism regulation effect, immune cells are activated, interferons are induced, viruses cannot survive and reproduce in porcine body cells, and the effect of resisting the porcine reproductive and respiratory syndromes is achieved.

Description

technical field [0001] The invention relates to the technical field of immunity, in particular to an immune preparation for preventing and treating porcine reproductive and respiratory syndrome. Background technique [0002] Porcine reproductive and respiratory syndrome (Porcine Reproductive and Respira-tion Syndrome, PRRS) is an acute contact infectious disease caused by porcine reproductive and respiratory syndrome virus, which mainly causes reproductive disorders in pregnant sows and respiratory symptoms in piglets, leading to Abortion, stillbirth, mummified fetus, weak piglets and other reproductive disorders and a large number of deaths of piglets. The disease is an acute and highly lethal infectious disease. The virus is highly pathogenic and spreads quickly. The morbidity and mortality of pigs are high. The incidence of piglets can reach 100%, and the mortality rate can reach more than 30%. The rate can reach more than 30%. Fattening pigs and sows can also die. [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P31/14
Inventor 孙霞
Owner QINGDAO HUAREN TECH INCUBATOR
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