Constant-temperature incubator for isolated perfused heart

Abstract

The invention discloses a constant-temperature incubator for an isolated perfused heart. The constant-temperature incubator for an isolated perfused heart comprises an incubator body and a mobile device, wherein a test tank and a heating tank are formed in the incubator body; the test tank is connected with the heating tank, is subjected to heat exchange with the heating tank through a heat conductor, and is communicated with an external liquid inlet pipe; a drain pipe is arranged at the bottom of the test tank; and the mobile device is located above the incubator body and is used for driving an external liquid inlet pipe to move forward and backward and up and down. According to the constant-temperature incubator, the isolated heart is put into the test tank; heat exchange is carried out between the test tank and the heating tank through the heat conductor so that a constant physiological temperature environment is provided for incubation of the isolated heart; the mobile device is used for driving the external liquid inlet pipe to synchronously move forward and backward and up and down together with the perfused isolated heart so as to ensure that the isolated heart can be adjusted to a proper position; the isolated heart is stably fixed through a transparent element and a heart fixing device; implementation of a photographing or electrocardiosignal recording and stimulating procedure is facilitated; and incubation of the isolated heart and detection of related tests are facilitated.

Description

technical field [0001] The invention relates to the technical field of medical instruments, in particular to a constant temperature incubator for isolated perfused hearts. Background technique [0002] In teaching and scientific research, it is often necessary to observe the function of the isolated perfused heart, such as: optical mapping, fluorescence detection, etc. At this time, it is necessary to place the heart in a constant temperature perfusion apparatus in order to maintain the function of the heart. Activity, to ensure the accuracy of detection indicators. [0003] The Chinese utility model patent with the publication number CN2581064Y discloses a constant temperature perfusion apparatus for isolated organs, which consists of a temperature control part, a constant temperature part, an oxygen feeding part, an infusion part, and a specimen tank. The temperature control part includes a temperature control shell, It is equipped with a temperature control circuit and a...

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Problems solved by technology

[0005] (1) There is no fixing device in the specimen tank, the heart cannot be fixed well, and it is difficult to ensure the accuracy of the detection index;

[0006] (2) The positions of the specimen tank and the infusion tube cannot be adjusted, which is inconvenient to operate and cannot meet the requirements of the detection test;

[0007] (3) The above-mentioned constant temperature perfusion instrument lacks electrocardiogram detection and stimulation / recording electrodes and other devices specially designed for heart function detection, and needs to be connected to an external device, which is very inconvenient and will not only affect the test results but also affect the cardiac activity;

[0008] (4) When the above-mentioned constant temperature perfusion apparatus is used for the relevant detection of the isolated heart, the activity of the isolated heart cannot be directly observed;

[0009] (5) The liquid and oxygen of the above-mentioned constant temperature perfusion instrument are separated, and the liquid is first heated and then enters the specimen tank, resulting in a very complicated structure of the instrument (such as setting heat dissipation windows, diversion tubes, three-way valves, multi-hole valves, etc.), and the success is high. Not conducive to mass promotion

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