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Traditional Chinese medicine for treating radiographic contrast nephropathy and preparation method

A technology of traditional Chinese medicine and medicinal materials, which is applied in the field of traditional Chinese medicine and preparation for the treatment of contrast nephropathy, which can solve the problems of only 0.6% to 1.25% and achieve the effects of low recurrence rate, definite curative effect, and small toxic and side effects

Inactive Publication Date: 2015-09-02
陆继香
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in a group of retrospective multiple myeloma observations after receiving contrast agents, the incidence of CAN was only 0.6% to 1.25%.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0053] When the dosage form of any one of the above-mentioned Chinese medicines is a tablet, its preparation method may further comprise the steps:

[0054] The first step is to fry the white lettuce with vinegar;

[0055] In the second step, mix Bailongtou, Banbiansu, Bianshanhong and Chaofengcao according to the stated ratio, add ethanol with an alcohol concentration of 70% to 80% that is 2 to 4 times that of the mixture, and heat and reflux to extract 2 to 4 Each time, reflux extraction for 1 hour to 2 hours each time, combine the extracts, use a tube centrifuge to remove impurities, and concentrate the extracts after removal of impurities under reduced pressure at 60°C to 70°C to the relative density at 60°C 1.05-1.10 liquid medicine, the concentrated liquid is dried into powder by spray drier, and mixed with the white lettuce fried in vinegar in proportion;

[0056] The third step is to mix Daheiyao, Donglima, Tibetan clove and Feicai according to the stated ratio, add e...

Embodiment 1

[0066] Embodiment 1: tablet

[0067] Take 130g of white lettuce, 450g of Bailongtou, 120g of Banbiansu, 180g of Bianshanhong, 120g of Chaofengcao, 180g of Daheiyao, 200g of Donglima, 190g of Tibetan Clove, 110g of Feicai, 400g of Hemorrhoids, 190g of Hemeng, 230g of yellow rattan, 130g of tamarisk, 160g of perennial orchid, 200g of sheath flower, 120g of Desmodium, 230g of Dajindao and 440g of lantern grass.

[0068] Its preparation method comprises the following steps:

[0069] The first step is to fry the white lettuce with vinegar;

[0070] In the second step, mix Bailongtou, Banbiansu, Bianshanhong and Chaofengcao according to the stated ratio, add 80% ethanol with an alcohol concentration 4 times that of the mixture, and heat and reflux for extraction 4 times, each reflux extraction 2 hours, combine the extracts, remove impurities by centrifugation with a tube centrifuge, concentrate the extracts after removal of impurities under reduced pressure at 70°C to a medicinal ...

Embodiment 2

[0074] Embodiment 2: capsules

[0075] Take 180g of white lettuce, 380g of Bailongtou, 150g of Banbiansu, 150g of Bianshanhong, 170g of Chaofengcao, 150g of Daheiyao, 250g of Donglima, 150g of Tibetan clove, 150g of Feicai, 420g of Hemencao, 160g of Hemeng, 250g of yellow rattan, 180g of tamarisk, 200g of perennial orchid, 150g of sheath flower, 150g of desmodium, 180g of dajindao and 390g of lantern grass.

[0076] Its preparation method comprises the following steps:

[0077] In the first step, the raw medicinal materials are mixed in proportion, put into a casserole and fried for 40 minutes, crushed into fine powder with a pulverizer, and sieved into a 200-mesh powder;

[0078] In the second step, add ethanol with an alcohol concentration of 80% that is 4 times the mass of the powder obtained in the first step, heat and reflux for 3 hours, extract 3 times, combine the extracts, filter to obtain the alcohol extract, and concentrate the alcohol extract under reduced pressure...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating radiographic contrast nephropathy and a preparation method. The traditional Chinese medicine comprises the following raw medicinal materials of lettuce stem and leaf, Indian lettuce root, common elsholtzia herb, common oxyspora root, cynanchum ascyrifolium, wingedstem inula root, edible debregeasia root and leaf, Neohymenopogon parasiticus, orange stonecrop herb and root, herb of bottle brush, aeschynomene indica, common fibraurea stem, Chinese tamarisk, Changnienia amoena Chien, amischotolype hispida, Herba Lysimachiae, ovate neolepisorus herb and peruvian groundcherry herb. The traditional Chinese medicine has the beneficial effects that the effect of treating the radiographic contrast nephropathy is obvious, the toxic and side effect is little, and the reoccurrence rate is low.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating contrast nephropathy and a preparation method thereof. Background technique [0002] With the development of radiodiagnostic technology and interventional therapy, contrast induced nephropathy (CIN) is more and more seen clinically, and contrast agent has become the third leading cause of hospital-acquired acute renal failure. The incidence of CIN in the general population is 0.6% to 6%, but in specific groups, such as the elderly, diabetes, chronic kidney disease, chronic heart insufficiency, acute myocardial infarction and other patients, the incidence can be as high as 20%. The incidence rate is as high as 40% to 90% in the high-risk factor population. [0003] Contrast agents can be divided into three categories according to their osmolarity: hyperosmolarity [>1400mOsm / (kg·H2...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P13/12
Inventor 陆继香袁明智
Owner 陆继香
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