Method for preparing hydrophilic lubrication coating layer on surface of inert high-molecular material and medical instrument

Abstract

The invention discloses a method for preparing a hydrophilic lubrication coating layer on a surface of an inert high-molecular material and a medical instrument. The method comprises the following steps: an inert high-molecular material is immersed into a grafting photoinitiator solution for 1-10min; the inert high-molecular material soaked with grafting photoinitiators is immersed into a grafting monomer solution for 5-20min, ultraviolet light irradiation modification and grafting polymerization are carried out and a grafting modification layer is formed on the surface of the inert high-molecular material; the inert high-molecular material after graft polymerisation is cleaned; the inert high-molecular material after cleaning is immersed into a hydrophilic gel solution for 1-10min; the hydrophilic gel solution attached to the surface of the inert high-molecular material is subjected to ultraviolet light polymerization solidification, and a hydrophilic gel layer is formed on the surface of the grafting modification layer. The hydrophilic lubrication coating layer prepared through the method has high hydrophilic lubricity and adhesive force.

Description

technical field [0001] The invention relates to the field of surface treatment of inert polymer materials, in particular to the field of surface treatment of medical inert polymer materials. Background technique [0002] With the development of interventional medicine, interventional catheter devices have been widely used in clinical treatment. At present, medical interventional materials, such as urinary catheters, cardiovascular catheters, and syringes, are mostly made of hydrophobic materials, such as polyurethane and silicone rubber. Although these materials have excellent mechanical properties and biocompatibility, as hydrophobic materials, when they are involved in the human body, they have a large friction force on tissues, and are easy to damage epithelial tissues such as the urethra and blood vessel walls, causing pain or burns, and are easy to Adsorbed bacteria cause concurrent inflammation. [0003] Therefore, the requirements for the performance of intervention...

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Problems solved by technology

[0012] The present invention provides a method for preparing a hydrophilic lubricating coating on the surface of an inert polymer material in order to solve the difficulties in forming a hydrophilic lubricating coating on the surface of an existing highly inert polymer device

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