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Qi and blood deficiency type migraine treating drug and preparation method thereof

A technology for qi and blood deficiency, migraine, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc. , to achieve the effect of good therapeutic effect, less resistance to drug resistance and low cost

Inactive Publication Date: 2015-07-15
李佃场
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these therapeutic methods have a single drug for treating migraine, are not highly targeted, and have a long course of treatment, which is prone to drug resistance, dependence, more side effects, and prolonged treatment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0081] In order to solve the above-mentioned technical problems, the present invention also provides a preparation method of a medicine for treating Qi and blood deficiency migraine, wherein, when the dosage form of the medicine is a tablet, the preparation method comprises the following steps:

[0082] The first step is to mix the raw materials in the drug in proportion, add ethanol with an alcohol concentration of 75-95% relative to the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extraction liquid; the dregs obtained by filtering are added with ethanol with an alcohol concentration of 85-95% relative to the quality of the dregs which is 1-2 times the mass of the dregs, heated and refluxed for 2-4 hours, extracted, and filtered to obtain a second extract; the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0083] In the s...

Embodiment 1

[0099] Embodiment 1 Tablet of the present invention

[0100] The preparation process of the oral medicine tablet of the present invention is: get kudzu 2000g, bitter sunflower 3000g, 2500g, Codonopsis 1500g, barley tiller 2500g, Atractylodes macrocephala 2200g, Sickle pod alfalfa 3000g, melaka 2200g, Chinese yam 2000g , Konjac 2800g, Acanthopanax 2500g, Dodder 2200g, Rehmannia glutinosa 2500g, Musk 2700g, Poria cocos 1800g, Angelica 2500g, Anthaceae 2800g, Paeoniae Alba 2000g, Polygonum leather leaf 2200g, Ligustrum lucidum 2500g, Hollyhock leaf yam 2700g, Fangfeng 2500g, Rhizoma Chuanxiong 3000g, Capsicum 2200g, Angelica dahurica 1800g, Grass sinensis 2000g, Ligusticum 2500g, Asarum 1900g, Domino fern 1800g, Prunella vulgaris 2500g, Budisma 2200g, Astragalus 2000g, Chrysanthemum 2500g, Wengcai Huang 2200g, black berry 2700g, Meconopsis meconopsis 2800g, licorice 2000g, catkin 2200g, bright reticulated fern 2700g, gymnastic vine 2500g, weed root 2500g, bitter pot vine 2200g an...

Embodiment 2

[0104] Embodiment 2 Capsules of the present invention

[0105] The preparation process of the oral medicine capsule of the present invention is: get kudzu 3000g, bitter sunflower 1800g, 2200g, Codonopsis 2000g, barley tiller 2500g, Atractylodes macrocephala 2800g, alfalfa 3000g, melon 3500g, Chinese yam 2500g , Konjac 2200g, Acanthopanax 2000g, Cuscuta 2500g, Rehmannia glutinosa 2200g, Musk 2800g, Poria cocos 3000g, Angelica 2500g, Anthaceae 3000g, White peony root 2500g, Polygonum leather leaf 3500g, Ligustrum lucidum 2000g, Hollyhock leaf yam 2200g, Fangfeng 2500g, Rhizoma Chuanxiong 3000g, Capsicum 2500g, Angelica dahurica 2200g, Grass sinensis 2500g, Ligusticum 2200g, Asarum 2500g, Domino fern 2800g, Prunella vulgaris 1800g, Budisma japonica 2500g, Astragalus 2500g, Chrysanthemum 3000g, Wengcai Huang 2500g, black berry 2800g, 3000g Meconopsis meconopsis, 2500g licorice, 2200g turnip, 2000g bright reticulate fern, 2500g gymnastics vine, 3000g root 3000g, 2500g bitter pot vi...

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PUM

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Abstract

The present invention discloses a qi and blood deficiency type migraine treating drug and a preparation method thereof. The bulk drugs in the qi and blood deficiency type migraine treating drug comprise: vitis flexuosa thunb, divaricate serpentroot herb and root, scorzonera austriaca willd, codonopsis pilosula, fruit of highland barley malt, atractylodes macrocephala, medicago archiducis-nicolai g.sirjaev, fissistigma oldhamii (hemsl.) merr, common yam rhizome, amorphophallus konjac, acanthopanax senticosus, dodder, radix rehmanniae preparata, musk, tuckahoe, angelica, dried large yellow croaker, cynanchum otophyllum, polygonum coriaceum, fructus ligustri lucidi, dioscorea althaeoides r. knuth, saposhnikovia divaricata, ligusticum chuanxiong hort, sambucus williamsii, angelica dahurica, fewleaf schnabelia herb, ligusticum sinense oliv, asarum, lepidogrammitis rostrata, prunella vulgaris, buddleja officinalis maxim, malva rotundifolia, chrysanthemum, viola philippica cav, cayratia japonica (thunb.) gagnep, meconopsis quintuplinervia regel, licorice root, pasta ulmi, phymatodes lucida (roxb.)ching, gymnema, hao tian pao root, fructus lagenariae gourdae stem, and amphibious crab. The qi and blood deficiency type migraine treating drug of the present invention has beneficial effects of qi and blood nourishing, qi and blood deficiency type migraine treating, syndrome differentiation treatment from the whole body, strong targeting property, direct efficacy on lesions, short treatment course, good treatment effect, low toxic-side effect, easy administration, recurrence resistance after cure, drug resistance generation resistance of patients, immunity improving, simple pharmaceutical production process, low cost and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating qi and blood deficiency migraine and a preparation method thereof. Background technique [0002] Migraine is a common clinical symptom, usually confined to the upper half of the skull, including the brow arch, the upper edge of the helix, and the pain above the line of the external occipital inion is collectively referred to as migraine. There are many causes of migraine. Neuralgia, intracranial infection, intracranial space-occupying lesions, cerebrovascular disease, extracranial head and face diseases, and systemic diseases such as acute infection and poisoning can all lead to migraine. The age of onset is common in youth, middle age and old age. [0003] According to the etiology of headache, the second edition of "International Classification of Headache Disorders" formulated by the International Headache Society in 2004 divides ...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P25/06A61K35/55A61K35/60A61K35/612
Inventor 李佃场
Owner 李佃场
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