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A kind of hangover composition and preparation method thereof

A composition and anti-alcohol technology, applied in the direction of drug combination, antidote, pharmaceutical formula, etc., can solve the problems of lack of products, accelerated ethanol metabolism, single action, etc., to protect the liver, promote alcohol metabolism and excretion, and prevent drunkenness. Effect

Active Publication Date: 2017-11-14
陕西中药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current commercially available anti-alcoholic agents have the following deficiencies: the effect is relatively single, mostly acting on the liver metabolic enzyme system, accelerating the metabolism of ethanol to reduce the damage to tissues and cells, antagonizing the toxic effect of ethanol metabolism-related substances on the liver, However, there is a lack of products that can act on multiple links and have comprehensive effects.

Method used

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  • A kind of hangover composition and preparation method thereof
  • A kind of hangover composition and preparation method thereof
  • A kind of hangover composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0047] The preparation of specific embodiment 1 extract dry powder

[0048] Pueraria japonica, Hovenia dulcis, hawthorn, Poria skin, reed root, tangerine peel, Schisandra chinensis, safflower, the raw materials are removed from the sundries and set aside. Take 4-8g of kudzu flower, 4-8g of Hovenia dulcis, 3-5g of hawthorn, 1-2.5g of poria cocos skin, 1-5g of reed root, 2-4g of tangerine peel, 3-5g of schisandra, and 0.1-0.25g of safflower. cook. For the first decoction, the soaking time of medicinal materials is 0.5-1.5 hours, the amount of water added is 8-12 times, and the extraction time is 1.0-2.0 hours. For the second decoction, add 6 to 10 times the amount of water, and the extraction time is 0.5 to 1.5 hours. Collect and combine the extracts that have been decocted for the second time, and the material-liquid specific gravity of the extracts is 1-2. Perform spray drying. The drying air inlet temperature is 180°C-210°C, the outlet air temperature is 80°C-110°C, the s...

specific Embodiment 2

[0049] The preparation of specific embodiment 2 granules

[0050] The dry powder obtained by spray-drying the extract of Example 1, adding an appropriate amount of absolute ethanol to granulate, passing through a 10-20 mesh sieve, drying in a constant temperature drying oven at 40-60°C for 3-4 hours, and then drying with a 10-20 mesh The granules are sieved to obtain granules, and the total flavonoids contained in the granules are not less than 1.5%.

specific Embodiment 3

[0051] The preparation of specific embodiment 3 buccal tablets

[0052] Spray-dry the obtained dry powder of the extract of Example 1, add magnesium stearate according to 2% of the dry powder mass, mix evenly, compress into tablets, and the pressure is 5-12KN to make buccal tablets, with a tablet weight of 0.5g, buccal tablets Containing total flavonoids is not less than 0.5%.

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Abstract

The present invention relates to an anti-alcoholic composition and a preparation method thereof. An antidote composition, comprising 3-12 parts of pueraria, 3-12 parts of Fructus aurantium, 3-12 parts of hawthorn, 1-9 parts of Poria bark, 2-9 parts of Schisandra chinensis, 2-9 parts of reed root, 2 to 12 parts of dried tangerine peel and 0.1 to 3 parts of safflower. A preparation method of an anti-alcoholic composition, comprising the following steps: 1. removing impurities in raw materials; 2. obtaining a primary extract by decoction and extraction once; 3. obtaining a secondary extract by secondary decoction and extraction; 4. After combining with the secondary extract, spray-drying is carried out to obtain the dry extract powder; 5. Molding to make granules, tablets or effervescent tablets. According to the mechanism and way of alcohol absorption, metabolism and excretion, the present invention adopts natural medicinal and edible Chinese medicinal materials as raw materials, and through modern extraction technology and preparation technology, the granules with excellent comprehensive anti-alcohol effect, safety, long-term consumption and no toxic and side effects are prepared. Buccal tablets, effervescent tablets.

Description

technical field [0001] The invention belongs to the technical field of health care and relates to a hangover composition, in particular to a hangover composition and a preparation method thereof. Background technique [0002] According to reports, there are more than 500 million drinkers in China, who cannot avoid drinking in social communication, work entertainment, etc. Among them, 60% of the drinkers drink unhealthily and drink too much; 50% of the drinkers are in sub-health and poor health. below its level. Therefore, drunkenness often occurs, and the problem of hangover also arises from it. [0003] Excessive drinking can damage the gastrointestinal tract, liver, nerves, cardiovascular and cerebrovascular organs, and can lead to mental disorders, gastric ulcers, fatty liver, alcoholic hepatitis, and cirrhosis of the liver. [0004] China is the country with the highest incidence of liver cancer in the world. According to statistics, the incidence of liver cancer in my...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P39/00
Inventor 朱爱华张亚利杨钧李存张艺芳任雷何爱武
Owner 陕西中药研究所
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