Lysostaphin compound enzyme disinfectant and preparation method thereof
A technology of lysostaphin and lysostaptococcus, which is applied in the directions of antibacterial drugs, drug combinations, pharmaceutical formulations, etc., can solve the problems of being unsuitable for large-scale production and application, complicated preparation process, low disinfection efficiency, etc. The effect of healing, high activity, good disinfection effect
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Embodiment 1
[0027] A lysostaphin composite enzyme disinfectant, comprising the following components in parts by mass: 6 parts of lysostaphin, 6 parts of antibacterial peptides, 6 parts of chlorhexidine acetate, 13 parts of sorbitol, 5 parts of sodium dihydrogen phosphate and 3 parts of disodium hydrogen phosphate.
[0028] The preparation method of above-mentioned lysostaphin composite enzyme disinfectant comprises the steps:
[0029] 1) Dissolve 6 parts of lysostaphin, 6 parts of antimicrobial peptide and 6 parts of chlorhexidine acetate in distilled water and mix well;
[0030] 2) Add 13 parts of sorbitol to the solution obtained in step 1), and shake well;
[0031] 3) Dissolve 5 parts of sodium dihydrogen phosphate and 3 parts of disodium hydrogen phosphate in distilled water and stir well, then add the obtained solution to the solution obtained in step 2), and shake well to obtain 1# disinfectant.
Embodiment 2
[0033] A lysostaphin composite enzyme disinfectant, comprising the following components in parts by mass: 8 parts of lysostaphin, 3 parts of antibacterial peptides, 3 parts of chlorhexidine acetate, 16 parts of sorbitol, 1.1 parts of sodium dihydrogen phosphate and 10 parts of disodium hydrogen phosphate.
[0034] The preparation method of above-mentioned lysostaphin composite enzyme disinfectant comprises the steps:
[0035] 1) Dissolve 8 parts of lysostaphin, 3 parts of antimicrobial peptide and 3 parts of chlorhexidine acetate in distilled water and mix well;
[0036] 2) Add 16 parts of sorbitol to the solution obtained in step 1), and shake well;
[0037] 3) Dissolve 1.1 parts of sodium dihydrogen phosphate and 10 parts of disodium hydrogen phosphate in distilled water and stir well, then add the obtained solution to the solution obtained in step 2), and shake well to obtain 2# disinfectant.
Embodiment 3
[0039] A lysostaphin composite enzyme disinfectant, comprising the following components in parts by mass: 2 parts of lysostaphin, 7 parts of antibacterial peptides, 9 parts of chlorhexidine acetate, 19 parts of sorbitol, 10 parts of sodium dihydrogen phosphate, Disodium hydrogen phosphate 1.1 parts.
[0040] The preparation method of above-mentioned lysostaphin composite enzyme disinfectant comprises the steps:
[0041] 1) Dissolve 2 parts of lysostaphin, 7 parts of antimicrobial peptide and 9 parts of chlorhexidine acetate in distilled water and mix well;
[0042] 2) Add 19 parts of sorbitol to the solution obtained in step 1), and shake well;
[0043] 3) Mix 10 parts of sodium dihydrogen phosphate and 1.1 parts of disodium hydrogen phosphate and stir well, then add the mixture of the two to the mixture obtained in step 2), shake well to get 3# disinfectant.
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