Production process of high-purity alpha-ethyl linolenate

Abstract

The invention discloses a production process of high-purity alpha-ethyl linolenate, and belongs to the field of chemistry. The process is characterized in that esterification reaction is adopted, raw materials include perilla oil, the perilla oil is saponified, acidified and washed to obtain fatty acid containing alpha-linolenic acid, the esterification reaction is directly carried out by adopting the washed fatty acid containing the alpha-linolenic acid, the esterification reaction is carried out at one time and carried out in a reaction device, the reaction device is connected with a water distribution device, azeotrope of ethanol and water is simultaneously evaporated into the water distribution device during the esterification reaction in a period of time, and the urine enveloping purification is carried out for the alpha-ethyl linolenate in a product after the esterification reaction. By adopting the production process, the production process of the alpha-ethyl linolenate is simplified, the productivity is greatly improved, the production time is shortened, and the production efficiency is improved.

Description

technical field [0001] The invention relates to a production process of α-ethyl linolenate, in particular to a production process of high-purity α-ethyl linolenate, which belongs to the field of chemistry. Background technique [0002] a-Linolenic acid, chemical name: Allcis-9,12,15-octadecatrienoic acid (Allcis-9,12,15-Octadecatrienoic acid) symbol: 18:3Δ9, 12, 15 or 18:3n— 3. ω-3; a-linolenic acid is one of the necessary nutrients for people, which is of great significance to the health of the human body. It is lacking in the human body and needs to be supplemented by other means. Its preparations also have many medical therapeutic effects. In medicine , the food industry is used as an additive or health care product. The purity of a-linolenic acid is low in nature, and its content in perilla oil and linseed oil is as high as 50%. Since the free state of a-linolenic acid is unstable, it is esterified The form of α-ethyl linolenate is convenient for large-scale industrial ...

AI Technical Summary

Problems solved by technology

[0002] a-Linolenic acid, chemical name: Allcis-9,12,15-octadecatrienoic acid (Allcis-9,12,15-Octadecatrienoic acid) symbol: 18:3Δ9, 12, 15 or 18:3n— 3. ω-3; a-linolenic acid is one of the necessary nutrients for people, which is of great significance to the health of the human body. It is lacking in the human body and needs to be supplemented by other means. Its preparations also have many medical therapeutic effects. In medicine , the food industry is used as an additive or health care product. The purity of a-linolenic acid is low in nature, and its content in perilla oil and linseed oil is as high as 50%. Since the free state of a-linolenic acid is unstable, it is esterified The form of α-ethyl linolenate is convenient for large-scale industrial application. There are not many reports on the production process of α-ethyl linolenate. Anyang Chemical Industry Group Co., Ltd. announced the development in the patent application number: 200510107355.1 The production process of a-linolenic acid ethyl ester is a production process of a-linolenic acid ethyl ester self-developed by its subsidiary Henan Linuo Biochemical Co., Ltd. The process flow is simply described as: perilla seed-pressing oil to obtain perilla oil —saponification—acidification—purification of α-linolenic acid—esterification—washing—dehydration—molecular distillation, and finally obtain ethyl α-linolenic acid. This technological process can obtain ethyl α-linolenic acid with a purity of more than 80%, but in practice There are the following problems in production: one is that the fatty acid containing a-linolenic acid after washing needs to be purified before esterification, and part of the product a-linolenic acid will be lost in the purification process, so that the final yield of ethyl a-linolenic acid It is greatly affected, which is not conducive to maximizing the yield. Using this process, the initial 100kg of perilla oil can finally obtain about 10kg of a-linolenic acid ethyl ester. Ethyl linolenate should not exceed 20kg; secondly, in order to make the esterification reaction complete, the esterification needs to be cooled to a certain extent to release the product, and then the temperature is raised to continue the esterification. Generally, two or more esterifications are used in production. The reaction time is at least 16 hours, and the esterification reaction takes a long time