Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Acyclovir pharmaceutical composition

A composition and medicine technology, which is applied in the directions of active ingredients of heterocyclic compounds, pharmaceutical formulations, medical preparations of non-active ingredients, etc. The effect of poor fragmentation, improved utilization, and no toxic and side effects

Active Publication Date: 2015-05-27
KAMP PHARMA
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to achieve a long-term stable effect, the oral tablet of this invention has complex prescriptions, large drug side effects, and high preparation consumption rate due to traditional tablet compression, which easily causes waste of raw and auxiliary materials in the preparation process and increases industrial production costs.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Acyclovir pharmaceutical composition
  • Acyclovir pharmaceutical composition
  • Acyclovir pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] prescription:

[0030] Acyclovir 100g

[0031] Starch 31.1g

[0032] Pregelatinized starch 15.0g

[0033] Hypromellose 15.0g

[0034] Sodium starch glycolate 5.2g

[0035] Magnesium stearate 1.7g

[0036] A total of 500 pieces were made

Embodiment 2

[0038] prescription:

[0039] Acyclovir 100g

[0040] Lactose 31.1g

[0041] Mannitol 15.0g

[0042] Hypromellose 15.0g

[0043] Croscarmellose Sodium 5.2g

[0044] Magnesium stearate 1.7g

[0045] A total of 500 pieces were made

Embodiment 3

[0047] prescription

[0048] Acyclovir 100g

[0049] Dextrin 31.1g

[0050] Microcrystalline Cellulose 15.0g

[0051] Methylcellulose 15.0g

[0052] Crospovidone 5.2g

[0053] Micronized silica gel 1.7g

[0054] A total of 500 pieces were made

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of pharmaceutical preparations, and in particular relates to an acyclovir pharmaceutical composition and a preparation method thereof. The acyclovir pharmaceutical composition disclosed by the invention is a mixture comprising the following components in percentage by mass: 28.2-60.9% of acyclovir, 10-50% of a filling agent, 5-15% of an adhesion agent, 1-5% of a disintegrating agent and 0.1-1.8% of a lubricating agent. The acyclovir pharmaceutical composition disclosed by the invention is scientific in formula, simple in preparation process, easy to prepare, low in loss rate, smooth in surface and good in colour, lustre and curative effect.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to an acyclovir pharmaceutical composition and a preparation method thereof. Background technique [0002] Acyclovir, also known as acyclovir (ACV for short), is a nucleoside antiviral drug with a chemical name of 9-(2-hydroxyethoxymethyl)guanine. In 1981, Wellcome Company first listed this product in the UK, trade name: Zovirax. In 1982, the FDA approved this product to be marketed in the United States. At present, aciclovir is one of the main medicines sold worldwide. Acyclovir is the homotype of acyclic deoxyguanosine, which is a component of DNA. Acyclovir is similar in structure, except that the cyclic sugar structure is replaced by an acyclic side chain. It is mainly used for various infections caused by herpes simplex virus, and can be used for initial or recurrent skin, mucous membrane, external genital infection and HSV infection in immunocompromise...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/20A61K47/36A61K47/38A61K47/32A61K31/522A61P31/12
Inventor 曾培安刘娟吴健民
Owner KAMP PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com