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Licorice-extract-containing emulsion and preparation method thereof

A technology of licorice extract and emulsion, applied in the field of daily chemicals, to achieve the effects of enhancing transdermal ability, enhancing application, and increasing water solubility

Inactive Publication Date: 2015-05-06
AESTHETIC TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There is no report about the emulsion containing licorice extract in the prior art

Method used

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  • Licorice-extract-containing emulsion and preparation method thereof
  • Licorice-extract-containing emulsion and preparation method thereof
  • Licorice-extract-containing emulsion and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The composition of the emulsion containing licorice extract in the present embodiment is as follows:

[0038]

[0039] The preparation mode of this emulsion containing licorice extract is as follows:

[0040] 1) Mix the above-mentioned licorice flavonoids, soybean lecithin, caprylic acid / capric triglyceride, Span 80, glycerin, and propylene glycol, and shear at a high speed at 8000 rpm until there is no visible solid in the system;

[0041] 2) Add Tween 80, polyoxyethylene castor oil and water to the product of step 1), shear at a high speed at 12,000 rpm to obtain colostrum, which is processed by a high-pressure homogenizer at a pressure of 800 bar, and circulated 5 times to obtain Transparent and clear emulsion containing licorice extract (licorice flavonoid lipid nanoemulsion).

Embodiment 2

[0043] The composition of the emulsion containing licorice extract in the present embodiment is as follows:

[0044]

[0045] The preparation mode of this emulsion containing licorice extract is as follows:

[0046] 1) According to the above prescription, the A component is sheared at a high speed under the condition of 12000rpm until there is no visible solid in the system;

[0047] 2) Add component B to the product of step 1), shear at 8000rpm at high speed to obtain colostrum, and process the colostrum with a high-pressure homogenizer at a pressure of 1200bar and cycle 7 times to obtain a transparent and clear product containing licorice extract Emulsion (licorice flavonoid lipid nanoemulsion).

Embodiment 3

[0049] The composition of the emulsion containing licorice extract in the present embodiment is as follows:

[0050]

[0051]

[0052] The preparation mode of this emulsion containing licorice extract is as follows:

[0053] 1) According to the above prescription, the A component is sheared at a high speed under the condition of 10000rpm until there is no visible solid in the system;

[0054] 2) Add component B to the product of step 1) and shear at a high speed at 10000rpm to obtain colostrum. The colostrum is processed by a high-pressure homogenizer at a pressure of 2000bar and circulated 10 times to obtain a transparent and clear licorice extract. Emulsion (licorice flavonoid lipid nanoemulsion).

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Abstract

The invention relates to the field of daily chemicals, in particular to a licorice-extract-containing emulsion and a preparation method thereof. The licorice-extract-containing emulsion comprises the following components in parts by weight: 0.01-10 parts of a licorice extract, 1-20 parts of phospholipid, 5-25 parts of oil, 0.5-20 parts of a nonionic surfactant and 60-90 parts of a dispersion medium, wherein the nonionic surfactant is selected from one or more of span-60, span-80, polyglycerol-10 oleate, polyglycerol monooleate, tween-80, polyoxyethylated castor oil and caprylocaproyl macrogolglycerides. Due to the presence of keratoderma, the active ingredient molecules difficultly pass through the skin obstacle to be absorbed by the organism; according to the licorice extract-containing emulsion, the licorice extract is wrapped in lipid nanoemulsion, so that the water solubility of the licorice extract can be effectively increased, the transdermal absorption capacity of the licorice extract is improved and the application of the licorice extract in the field of skin external use is strengthened.

Description

technical field [0001] The invention relates to the field of daily chemicals, in particular to an emulsion containing licorice extract and a preparation method thereof. Background technique [0002] Glycyrrhizic Flavone is a kind of component with strong biological activity extracted from licorice root and rhizome. Glycyrrhizic flavone is insoluble in water and various oils and esters, but soluble in ethanol, propylene glycol, glycerin and some organic solvents. [0003] After searching, it was found that the invention patent application with publication number CN102140144A also disclosed a production method of water-soluble licorice flavonoids. In absolute ethanol and at room temperature -50°C, licorice flavonoids and cyclodextrin were reacted for 0.5 to 2 hours, dried , dissolved in deionized water, and filtered; the weight ratio of the licorice flavonoids and cyclodextrin is 4-8:1. [0004] The invention patent application with the publication number CN102949440A disclos...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/06A61Q19/08
Inventor 陈光李金环曹凤杰
Owner AESTHETIC TECH BEIJING
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