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Traditional Chinese medicine for treating depression after myocardial infarction due to liver stangation and spleen deficiency as well as preparation method thereof

A technology for liver stagnation and spleen deficiency and myocardial infarction, which is applied in the field of traditional Chinese medicine and preparation for treating depression after myocardial infarction of liver stagnation and spleen deficiency type, can solve the problems of non-objectifiable diagnosis of depression, delayed condition of depression, difficulty in correct diagnosis, etc. Effective and not easy to recur, break the effect of large side effects and short course of treatment

Inactive Publication Date: 2015-04-22
刘德彬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because of the diversification, complexity, somatization and non-objectification of symptoms, the diagnosis of depression brings certain troubles
At present, the diagnosis of depression mainly depends on the scale diagnosis and the doctor's experience without objective indications. Doctors and patients have strong subjective consciousness; in addition, many patients actively avoid or deny certain symptoms due to their bias in understanding the disease. Difficulty in correctly diagnosing the disease
In addition, a large number of patients moved between the internal medicine clinics of general hospitals instead of seeing a doctor in a specialized hospital or specialist clinic, which caused delays in the treatment of depression.

Method used

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Examples

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Effect test

preparation example Construction

[0049] Wherein, when the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0050] The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixture, heat and reflux for 1 to 3 hours, extract, and filter to obtain the first extraction Liquid, the dregs obtained by filtering are then added with ethanol with an alcohol concentration of 85% to 95% relative to the mass of the dregs, which is 1 to 2 times the mass of the dregs, heated and refluxed for 1 to 3 hours, extracted, filtered to obtain a second extract, and the second extract The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0051] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 ...

Embodiment 1

[0058] Embodiment 1: the capsule prepared by the present invention

[0059] Take 290g Bupleurum, 70g Melon Seed Gold, 230g Angelica, 310g Paeoniae Alba, 130g Hypericum perforatum, 380g fried Atractylodes macrocephala, 340g Poria cocos, 250g bee milk, 130g roasted licorice, 420g fried Suanzaoren, 180g Panax penicillium, 150g turmeric, American ginseng 300g, Trichosanthes 140g, Shichangpu 270g, Qingtou fungus 220g, Cyperus cyperi 180g, tangerine peel 230g, Yushanxiong 70g, paeonol 240g, gardenia 140g and dry rock gangue 150g;

[0060] Its preparation method comprises the following steps:

[0061]The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, filter to obtain the first extract, and filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, h...

Embodiment 2

[0064] Embodiment 2: powder injection prepared by the present invention

[0065] Take 260g of Bupleurum, 80g of Melon Seed Gold, 250g of Angelica, 340g of Paeoniae Alba, 110g of Hypericum perforatum, 400g of fried Atractylodes macrocephala, 320g of Poria cocos, 270g of bee milk, 150g of roasted licorice, 450g of fried Suanzaoren, 160g of Wujia, 190g of turmeric, American ginseng 260g, Trichosanthes 110g, Shichangpu 290g, Qingtou fungus 210g, Cyperus cyperi 70g, tangerine peel 210g, Yushanxiong 100g, paeonol 220g, gardenia 120g and dry rock gangue 130g;

[0066] Its preparation method comprises the following steps:

[0067] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 4 μm and nano-sized particles with a volume average particle size of less than 0.1 μm , the powder yield of the mixed powder is at least 90%;

...

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Abstract

The invention provides a traditional Chinese medicine for treating depression after myocardial infarction due to liver stangation and spleen deficiency as well as a preparation method thereof. The traditional Chinese medicine comprises the following raw materials: radix bupleuri, Japanese polygala, Chinese angelica, white peony root, hypericum perforatum, fried atractylodes, Poria cocos, royal jelly, honey-fried licorice root, fried spine date seed, Eleutherococcus brachypus, curcuma tuber, american ginseng, Trichosanthes kirilowii Maxim, grass-leaved sweetflag rhizome, russula virescens, rhizoma cyperi, dried orange peel, Conioselinum morrisonense Hayata, cortex moutan, cape jasmine and all-grass of Tomentose Corydalis. The traditional Chinese medicine has the beneficial effect that a traditional Chinese medicine syndrome differentiation treatment principle is abided, the traditional Chinese medicine has the advantages of strong pertinency, short treatment course, fast effectiveness and difficult recurrence when the depression after myocardial infarction due to liver stangation and spleen deficiency is treated, can break the defects of large side-effect of a traditional western medicine anti-depression medicines, large adverse reaction and easy recurrence, and can overcome the disadvantage that a Chinese patent medicine can not apply medicine according to indications.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine for treating post-myocardial infarction depression of liver stagnation and spleen deficiency type and a preparation method thereof. Background technique [0002] Depression after myocardial infarction is a common complication after myocardial infarction. The main clinical manifestations are depression and lack of happiness, accompanied by symptoms such as insomnia, fatigue, decreased labor force, weight loss, pessimism and despair, and even suicidal tendencies in severe cases. Seriously affect the treatment effect and quality of life of patients with myocardial infarction. Depression is now considered to be an independent risk factor affecting the prognosis of myocardial infarction. In recent years, the antidepressant treatment of patients with depression after myocardial infarction has been paid more and more atten...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10A61P25/24A61K35/644
Inventor 刘德彬
Owner 刘德彬
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