Method for manufacturing immediate dental implants with periodontal bioactivity

Abstract

The invention relates to a manufacturing method of an immediate dental implant with periodontal bioactivity, comprising the following steps: (1) preparing a pure titanium or titanium alloy implant core; (2) preparing a self-curing calcium magnesium phosphate powder; (3) preparing a collagen solution (4) Preparation of artificially synthesized substance P polypeptide; (5) Preparation of SP cross-linked collagen matrix; (6) Calcium magnesium phosphate powder mixed with SP cross-linked collagen matrix to prepare bioactive paste; (7) Bioactive paste Coating the root of the implant core, pressurizing, solidifying and freeze-drying to make an artificial tooth root with periodontal bioactivity; (8) connecting the crown of the implant core to an artificial crown suitable for the shape of the missing tooth to make an immediate implant. By constructing the artificial tooth root with bionic cementum structure, the prepared dental implant has some life characteristics of natural implanted teeth, has the biological activity of autonomous periodontal healing, can be implanted immediately after tooth extraction, significantly shortens the restoration time of missing teeth, and improves planting success rate.

Description

technical field [0001] The invention belongs to the technical field of dental artificial implants, and relates to a method for manufacturing biologically active dental implants, in particular to a method that can be implanted immediately after tooth extraction and actively induces the formation of osseointegration between the root of the implant and the bone tissue of the alveolar socket dental implant manufacturing method. Background technique [0002] Dental implant (dental implant) is called the third pair of teeth of human beings and has become a symbolic technology of modern stomatology. The development of modern dental implant technology is based on the theory of osseointegration (or osseointegration) proposed by Branemark, the father of implant in the 1960s. The American Academy of Dental Implantology defines osseointegration as: normal remodeled bone is in direct contact with the implant, soft tissue can be seen under a light-free microscope, and the load of the imp...

AI Technical Summary

Problems solved by technology

However, these growth factors are macromolecular proteins, and there are many problems in acquisition, synthesis, localization, delivery, and activity control, especially on the surface of titanium metal implants, how to load organic biomolecules, how to stably maintain their biological activity, and how to To ensure its biological safety, there are still many technical bottlenecks, and there is still a big gap from the actual clinical application conditions of dental implants

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