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Traditional Chinese medicine preparation for treating non-suppurative otitis media and preparation method thereof

A traditional Chinese medicine preparation and a non-suppurative technology, which are applied in the field of traditional Chinese medicine preparations for treating non-suppurative otitis media and their preparation, can solve the problems of large toxic and side effects, frequent morbidity in children, adverse effects on children's growth, and the like, and achieve less toxic and side effects and exact curative effect. Effect

Inactive Publication Date: 2015-04-08
杨纪英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the effect is not very satisfactory, and children with this disease often suffer from the disease, and the side effects of western medicines are relatively large, which has adverse effects on children's growth.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040] The present invention also provides the preparation method of above-mentioned Chinese medicine preparation, the dosage form of described Chinese medicine preparation is a tablet, and its preparation method comprises the following steps:

[0041] Step 1: Mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 80-90% that is 5-7 times the mass of the mixture, heat and reflux for 2-4 hours, extract, and filter to obtain the first extraction liquid, the dregs obtained by filtering are then added with ethanol with an alcohol concentration of 2 to 5 times that of the dregs, heated to reflux for 2 to 3 hours, extracted, filtered to obtain a second extract, and the first extract Combine with the second extract, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste;

[0042] The second step: place the dry paste obtained in the first step to pulverize in an ultrafin...

Embodiment 1

[0048] Embodiment 1: tablet

[0049] Take 200g of Yunnan bitter vegetable, 100g of ginger, 300g of sclerophyllum, 250g of sarcocarp, 300g of red Swiss wood, 250g of paraffin red, 400g of Tianshui antweed, 150g of Zhedihuang, 150g of fish brain stone, 350g of mountain alum leaf, 80g Corydalis, 100g Diguniu, 350g Single Kidney Grass, 250g Kusheng Ye and 200g Huangwan;

[0050] Prepare as follows:

[0051] The first step: mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85% that is 7 times the mass of the mixture, heat and reflux for 2 hours, extract, filter to obtain the first extract, and filter the obtained medicinal Then add ethanol with an alcohol concentration of 85% to the dregs, which is 4 times the mass of the dregs, heat and reflux for 2 hours, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under reduced pressure to remove et...

Embodiment 2

[0054] Embodiment 2: Granules

[0055] Take 250g of Yunnan bitter vegetable, 150g of clump ginger, 350g of sclerophyllum, 300g of sarcocarp, 250g of red mulberry, 300g of paraffin red, 350g of Tianshui antweed, 200g of Zhedihuang, 120g of fish brain stone, 400g of mountain alum leaf, 100g Corydalis, 80g Diguniu, 300g Single Kidney Grass, 300g Kusheng Ye and 250g Huangwan;

[0056] Prepare as follows:

[0057] The first step: mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 5 times that of the mixture and be 90% ethanol, heat to boiling and reflux for 5 hours, filter, and slow down the mixture at a rate of 3ml per minute by percolation method. Slow percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.06Mpa to a paste with a relative density of 1.12 at 70°C, spray dry, the inlet air temperature of the spray dryer is 150°C, and the outlet air temperature is 90°C. Then pulverized into po...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating non-suppurative otitis media and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following medicinal materials: picris divaricata, cheilocostus speciosus, melandryi firmi herba, drymoglossum piloselloides presl, cornus alba, fish pelargonium flower, asiatic cudweed, rehmannia chingii, asteriscus pseudosciaenae, symplocos sumuntia leaves, turkey corn, euroleon sinicus, habenaria petelotii gagnep, torenia vagans roxb and herb of shady groundsel. The traditional Chinese medicine preparation has an obvious curative effect on treating non-suppurative otitis media and has little toxic side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating non-suppurative otitis media and a preparation method thereof. Background technique [0002] Non-suppurative otitis media is a non-suppurative inflammatory disease of the middle ear characterized by middle ear effusion and hearing loss. Serous otitis media, serous-mucinous otitis media, aseptic otitis media. If the effusion is thick and jelly-like, it is also called glue ear. After upper respiratory tract infection, the main symptoms are ear fullness, distant hearing and hearing loss. Otology examination shows that the tympanic membrane is amber or orange, air-liquid level or bubbles can also be seen, and the activity of the tympanic membrane is reduced. Non-suppurative otitis media is more common in children. It can cause hearing loss in children and affect speech an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61P27/16A61K35/60A61K35/64A61K9/20A61K9/16
CPCA61K9/1652A61K9/2059A61K35/60A61K36/11A61K36/185A61K36/28A61K36/36A61K36/40A61K36/66A61K36/80A61K36/804A61K36/898A61K36/906A61K2236/333A61K2236/39A61K2300/00
Inventor 杨纪英
Owner 杨纪英
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