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Traditional Chinese medicine preparation for treatment of idiopathic trigeminal neuralgia and preparation method thereof

A technology for trigeminal neuralgia and traditional Chinese medicine preparations, which can be used in pharmaceutical formulations, nervous system diseases, medical preparations containing active ingredients, etc., and can solve problems such as drug adaptation and dose increase

Inactive Publication Date: 2015-04-01
QINGDAO HENGBO INSTR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In addition, often taking carbamazepine-like western medicines can easily lead to drug adaptation. If you want to maintain a certain curative effect, you have to increase the dose, forming a vicious circle

Method used

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  • Traditional Chinese medicine preparation for treatment of idiopathic trigeminal neuralgia and preparation method thereof
  • Traditional Chinese medicine preparation for treatment of idiopathic trigeminal neuralgia and preparation method thereof
  • Traditional Chinese medicine preparation for treatment of idiopathic trigeminal neuralgia and preparation method thereof

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preparation example Construction

[0060] The preparation method of tablet of the present invention comprises: first with 1300g of scorpion, 1200g of white silkworm, 1100g of earthworm, 1300g of cicada slough, after being washed with water, pulverize by pulverizer, and the fineness of medicine powder reaches more than 100 orders; Extracted twice by adding ethanol, the amount of ethanol is 10 times of the sum of the weight parts of the raw materials, heated and refluxed for 30 minutes to 45 minutes each time, the two extracts are filtered and then combined and left standing; the filtrate is left standing for later use ; Then Gujingcao 1200g, Rhizoma Cyperi 1300g, Curcuma 1200g, Chuanxiong 1200g, Baiziren 1200g, Corydalis 1200g, Fangfeng 1100g, Gastrodia elata 1200g, Polygala 1100g, Ligustrum lucidum 1100g, Gentiana 1200g, Nocturnal vine 1200g, semi 1200g lotus branch, 1100g salvia miltiorrhiza, 1200g white peony, 1200g angelica, 1200g vitex, 1300g uncaria, 1100g epimedium, 1200g mother-of-pearl, soak in ethanol, ...

Embodiment

[0147] Embodiment: ancient certain, female, 48 years old, was first diagnosed in July, 2011. Self-reported trigeminal neuralgia for more than 5 years, recurrent attacks, sometimes mild and sometimes severe, alternating left and right pain, especially on the right side, showing persistent throbbing pain, paroxysmal aggravation after fatigue or emotional agitation, less menstrual flow, blood clots , Dysmenorrhea, accompanied by nausea, vomiting, dizziness, tinnitus. In the past week, trigeminal neuralgia had frequent attacks and the pain was intensified. EEG topography, cerebral blood flow map, and head CT were performed and no abnormalities were found. Western medicine diagnosis is: trigeminal neuralgia. The curative effect of medicines such as craniotin, zhennaoning, migraining, and sibeline after taking it is not good. Blood pressure 14.7 / 10kPa (110 / 75mmHg), pale tongue, thin white fur, stringy and slippery pulse. The syndrome belongs to exogenous evil invasion, qi stagnat...

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Abstract

The invention provides a traditional Chinese medicine preparation for treatment of idiopathic trigeminal neuralgia. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 10-20 parts of flos eriocauli, 10-20 parts of rhizoma cyperi, 10-20 parts of rhizoma zedoariae, 10-20 parts of rhizoma ligustici wallichii, 10-20 parts of semen platycladi, 10-20 parts of corydalis yanhusuo, 10-20 parts of saposhnicovia divaricata, 10-20 parts of gastrodia, 10-20 parts of periostracum cicada, 10-20 parts of polygala tenuifolia, 10-20 parts of fructus ligustri lucidi, 10-20 parts of gentiana scabra bge, 10-20 parts of tuber fleeceflower stems, 10-20 parts of scutellariae barbatae, 10-20 parts of salvia miltiorrhiza, 10-20 parts of radix paeoniae alba, 10-20 parts of angelica sinensis, 10-20 parts of fructus viticis, 10-20 parts of uncaria, 10-20 parts of scorpion, 10-20 parts of epimedium, 10-20 parts of white batryticated silkworm, 10-20 parts of lumbricus, and 10-20 parts of mother-of-pearl. The traditional Chinese medicine preparation disclosed by the invention is implemented by taking expelling wind and relieving convulsion, eliminating phlegm and dissolving turbidity, suppressing hyperactive liver and subsiding yang, relieving muscular spasm and tranquilizing the mind as a principle. The preparation integrates the effects of improving pain, realizing herbal treatment and resisting spasm, so that damaged cranial nerves can be restored and regenerated fundamentally; and by using the interaction of drugs, side effects which are possibly caused by western medicines are offset or resisted, so that the preparation can be taken at ease by patients; and the preparation takes effect quickly, and has a good long-term curative effect, and the idiopathic trigeminal neuralgia treated by using the preparation is difficult to recur.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating primary trigeminal neuralgia and a preparation method thereof. Background technique [0002] Trigeminal neuralgia is the most common cranial nerve disease. It is mainly manifested by recurrent paroxysmal severe pain in the distribution area of ​​the trigeminal nerve on one side of the face. The incidence rate in domestic statistics is 52.2 / 100,000. Females are slightly more than males. May increase with age. Trigeminal neuralgia mostly occurs in middle-aged and elderly people, and the right side is more common than the left side. The characteristics of the disease are: in the trigeminal nerve distribution area of ​​the head and face, the onset is sudden, sudden arrest, lightning-like, knife-like, burning-like, intractable, unbearable severe pain. Talking, washing your f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P25/02A61K35/646A61K35/64A61K35/62A61K35/618
CPCA61K36/88A61K9/2059A61K9/2068A61K35/618A61K35/62A61K35/646A61K36/14A61K36/232A61K36/236A61K36/238A61K36/296A61K36/515A61K36/537A61K36/539A61K36/638A61K36/65A61K36/66A61K36/69A61K36/704A61K36/71A61K36/74A61K36/85A61K36/8905A61K36/8988A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 不公告发明人
Owner QINGDAO HENGBO INSTR
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