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Medical polyurethane thin film and preparation method thereof

A polyurethane film and polyurethane technology, applied in medical science, bandages, absorbent pads, etc., can solve problems such as limited application, accumulation of exudate under the film, and ineffective water absorption, and achieve excellent mechanical properties and good water vapor transmission rate Effect

Active Publication Date: 2015-03-25
南通华盛高聚物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its disadvantage is that the moisture permeability cannot meet the needs of practical applications, which may easily lead to the accumulation of exudate under the membrane and induce infection
[0005] Polyurethane film has good elasticity, flexibility, wear resistance and tear resistance, and has good compliance, can be very good waterproof, antibacterial, and has excellent biocompatibility, and it is increasingly used in dressing applications The more attention is paid to it, and the polyurethane film as a dressing mainly relies on the transfer of water vapor to control the exudate, but the moisture permeability of the pure polyurethane film is not high, and the water absorption effect is not obvious, which greatly limits its application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A medical polyurethane film, the raw materials in parts by weight include: 80 parts of polyurethane, 15 parts of polyethylene, 8 parts of polyethylene glycol, 5 parts of ultrafine chitosan powder, 3 parts of dihexyl phthalate, 4, 4 parts of 5-epoxytetrahydrophthalate dioctyl ester, 6 parts of epoxy soybean oil, 7 parts of benzyl silicone oil, 5 parts of calcium carbonate, 4 parts of N-cyclohexylethanolamine, 3 parts of triphenyl phosphite , 7 parts of 1,4-dioxane, 8 parts of N,N-dimethylformamide.

[0019] The molecular weight of the polyethylene glycol is 2000, and the particle size of the ultrafine chitosan powder is 20 μm.

[0020] The preparation method of the above-mentioned medical polyurethane film includes the following steps:

[0021] Step 1. Add each component to the mixing mixer, stir and mix evenly, the stirring speed is 300 rpm, and the stirring time is 40 minutes to obtain the mixture;

[0022] Step 2, adding the mixture material obtained in step 1 into the react...

Embodiment 2

[0025] A medical polyurethane film, the raw materials in parts by weight include: 95 parts of polyurethane, 18 parts of polyethylene, 12 parts of polyethylene glycol, 7 parts of ultrafine chitosan powder, 5 parts of dihexyl phthalate, 4, 7 parts of 5-epoxytetrahydrophthalate dioctyl ester, 9 parts of epoxy soybean oil, 9 parts of benzyl silicone oil, 8 parts of calcium carbonate, 6 parts of N-cyclohexylethanolamine, 4 parts of triphenyl phosphite , 10 parts of 1,4-dioxane, 10 parts of N,N-dimethylformamide.

[0026] The molecular weight of the polyethylene glycol is 2500, and the particle size of the ultrafine chitosan powder is 40 μm.

[0027] The preparation method of the above-mentioned medical polyurethane film includes the following steps:

[0028] Step 1. Add each component to the mixing mixer, stir and mix uniformly, the stirring speed is 400rpm, and the stirring time is 20min to obtain the mixture;

[0029] Step 2, adding the mixture material obtained in step 1 into the react...

Embodiment 3

[0032] A medical polyurethane film, the raw materials in parts by weight include: 105 parts of polyurethane, 20 parts of polyethylene, 15 parts of polyethylene glycol, 9 parts of ultrafine chitosan powder, 6 parts of dihexyl phthalate, 4, 9 parts of 5-epoxytetrahydrophthalate dioctyl ester, 12 parts of epoxy soybean oil, 10 parts of benzyl silicone oil, 12 parts of calcium carbonate, 7 parts of N-cyclohexylethanolamine, 5 parts of triphenyl phosphite , 12 parts of 1,4-dioxane, 13 parts of N,N-dimethylformamide.

[0033] The molecular weight of the polyethylene glycol is 3000, and the particle size of the ultrafine chitosan powder is 40 μm.

[0034] The preparation method of the above-mentioned medical polyurethane film includes the following steps:

[0035] Step 1. Add each component to the mixing mixer, stir and mix evenly, the stirring speed is 350 rpm, and the stirring time is 30 min to obtain the mixture;

[0036] Step 2, adding the mixture material obtained in step 1 to the reac...

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Abstract

The invention provides a medical polyurethane thin film and a preparation method thereof. The polyurethane thin film comprises the following raw materials: polyurethane, polyethylene, polyethylene glycol, ultra-fine chitosan powder, dihexyl phthalate, 4,5-epoxytetrahydrophthalate, epoxidized soybean oil, polymethylphenyl siloxane fluid, calcium carbonate, N-cyclohexylethanolamine, triphenyl phosphite, 1,4-dioxane and N,N-dimethylformamide. The preparation method comprises the following steps: firstly feeding each component into a mixing stirrer, uniformly mixing and stirring, then adding an obtained mixed material into a reaction kettle, heating, performing stirring reaction, finally pouring an obtained film preparing liquid into one side of a glassine paper matrix, uniformly pushing the liquid to the other side by using a coating machine, putting a coated film preparing liquid and the matrix into clear water together, taking out after film forming, washing, drying, and stripping off from the matrix to obtain the medical polyurethane thin film. The medical polyurethane thin film provided by the invention has excellent mechanical performance, and also has a very good water vapor transmission rate.

Description

Technical field [0001] The invention belongs to the technical field of medical polymer materials, and specifically relates to a medical polyurethane film and a preparation method thereof. Background technique [0002] Polyurethane (PU) is the abbreviation for polyurethane. It is a general term for polymers containing repeating urethane structural units (-NHCOO- groups) on the polymer backbone. Segment copolymer. The polyurethane elastomer contains blocks with dissimilar chemical properties, namely soft and hard segments. Due to the incompatibility of soft and hard segments, polyurethane has obvious microphase separation, which is very similar to biofilms, so it has good physical properties, biocompatibility and blood compatibility, and is a widely used medical device. Polymer Materials. [0003] Since its inception in 1937, polyurethane has been widely used in the biomedical field due to its excellent physical and chemical properties, low toxicity, good tissue and blood compatib...

Claims

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Application Information

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IPC IPC(8): A61L15/26A61L15/42A61L15/24A61L15/28A61L15/34
Inventor 郭玉芹李永超刘乐峰
Owner 南通华盛高聚物科技股份有限公司
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