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Composition conducive to lowering of cholesterol, and preparation method, preparation and application of composition

A technology of composition and cholesterol, which is applied in the field of food and medicine, can solve the problems of restricting the application of Moringa oleifera leaves, strong pungent and irritating, and large dosage, and achieve the effect of increasing cholesterol-lowering function, strengthening cholesterol-lowering function, and simple preparation process Effect

Inactive Publication Date: 2015-03-25
云南云药医药研究有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Yet the Moringa leaf product on the market is all with the Moringa leaf crude product as raw material, makes the characteristic that the commercially available Moringa leaf product still is pungent and irritating, and mouthfeel is relatively poor; Secondly, the active ingredient in the Moringa leaf has not been Extraction and enrichment, the product has low active ingredient content and large dosage, and the product has the disadvantages of unclear nutritional components, which limits the further application of Moringa oleifera leaves

Method used

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  • Composition conducive to lowering of cholesterol, and preparation method, preparation and application of composition
  • Composition conducive to lowering of cholesterol, and preparation method, preparation and application of composition

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preparation example Construction

[0021] The preparation method of the composition helpful for lowering cholesterol according to the present invention includes the steps of pretreatment, extraction and posttreatment, specifically including:

[0022] A. Pretreatment: Weighing according to the ratio of raw materials, crushing and sieving respectively for subsequent use;

[0023] B. Extraction: Mix the raw materials after pretreatment, add an ethanol solution with a mass percentage concentration of 30-70% of the solid-liquid volume ratio of 8-40 times, and extract at 15-60°C for 2-4 times, and the extraction time is 12~48h, filter and concentrate at low temperature to obtain the extract with a relative density of 1.1~1.3 for later use;

[0024] C. Post-processing: the extract is dried, pulverized and sieved to obtain the target composition.

[0025] The crushing and sieving described in the A step is passing through a 20-100 mesh sieve.

[0026] The ethanol solution described in the B step has a mass percentage...

Embodiment 1

[0033] Take 100 kg of Moringa oleifera leaves, 125 kg of hawthorn, and 175 kg of orange peel, respectively crush them through a 20-mesh sieve, mix them and put them into an extraction tank, add 3200 kg of 50% ethanol solution, heat up to 45°C, extract at a constant temperature for 24 h, and repeat the extraction three times. The obtained extracts were combined, and the extracts were concentrated under reduced pressure to 1 / 5 of the original volume (relative density at 20°C was 1.1) to obtain an extract, which was dried, pulverized, and passed through a 40-mesh sieve to obtain the target composition.

Embodiment 2

[0035] Take 300 kg of Moringa leaves, 100 kg of hawthorn, and 50 kg of orange peel, respectively crush them through a 100-mesh sieve and put them into an extraction tank, add 4500 kg of 65% ethanol solution, heat up to 55°C, extract at a constant temperature for 24 h, and repeat the extraction twice , combined the obtained extracts; the extracts were concentrated under reduced pressure to 1 / 3 of the original volume (relative density at 20°C was 1.3) to obtain extracts, and the extracts were dried, crushed, and passed through a 120-mesh sieve to obtain the target composition.

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Abstract

The invention discloses a composition conducive to lowering of cholesterol, and a preparation method, a preparation and an application of the composition. The composition conducive to lowering of cholesterol is prepared from the following raw materials in parts by weight: 100-600 parts of horseradish tree leaves, 100-350 parts of hawthorns and 50-300 parts of orange peel by pretreatment, extraction and post-treatment. The horseradish tree leaves in the composition are capable of providing essential nutrient substances in human bodies and improving body health, have the efficacies of lowering cholesterol and reducing blood fat; and the hawthorn has the efficacies of promoting digestion, invigorating the stomach, promoting the circulation of qi, dissipating blood stasis and the like, is rich in abundant hesperetin and hesperidin, is capable of inhibiting the activity of reductase and cholesterol enzyme in plasma and liver, increasing emission of cholesterol, and has the functions of lowering cholesterol, reducing blood fat, resisting atherosclerosis and reducing cardiovascular diseases.

Description

technical field [0001] The invention belongs to the technical field of food and medicine, and in particular relates to a composition helpful for lowering cholesterol and a preparation method, preparation and application thereof. Background technique [0002] According to statistics, about 3 million people die of cardiovascular disease in China every year, and about 8,000 people die every day. The World Health Organization predicts that by 2030, cardiovascular disease will still be an important cause of death, affecting the health of about 23.6 million people around the world. . Hypercholesterolemia is the main factor that induces cardiovascular disease. [0003] Relevant studies have shown that Moringa leaves have various pharmacological activities such as anti-oxidation, antibacterial, anti-tumor, anti-cancer, liver protection, lowering blood pressure, and lowering cholesterol, and have broad application prospects in food, medicine and other fields. At present, domestic r...

Claims

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Application Information

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IPC IPC(8): A61K36/752A23L1/29A61P3/06A23L33/00
CPCA61K9/14A61K9/16A61K9/20A61K9/2068A61K9/48A61K36/185A61K36/734A61K36/752A61K2236/15A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 周志宏周树雅刘菲菲张昊王兵
Owner 云南云药医药研究有限公司
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