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Application of American cockroach lipid in tumor prevention

A Periplaneta americana, anti-tumor technology, applied in anti-tumor drugs, medical preparations containing active ingredients, drug delivery, etc., can solve the problems of insufficient attention to drug research and development

Inactive Publication Date: 2015-03-18
SICHUAN GOODDOCTOR PANXI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is rare to see Chinese patent medicines directly used for tumor treatment. This situation does not mean that there are no medicines for treating tumors in traditional Chinese medicine, but that the research and development of such medicines is not enough attention, and there is still a huge potential to be tapped

Method used

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  • Application of American cockroach lipid in tumor prevention

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1 The preparation of Periplaneta americana oil of the present invention

[0029] (1) Sample 1: Take 500g of dried Periplaneta americana, use 70%~90% ethanol heat reflux to extract after crushing, combine and concentrate under reduced pressure to a small volume, and then use any of n-hexane, sherwood oil, and acetone One solvent was used for extraction, and the extract was concentrated to dryness at room temperature to obtain Extract One.

[0030] (2) Sample 2: Take 500g of dried Periplaneta americana whole worm, and use CO 2 Supercritical fluid extraction, the extract 2 is obtained after being refined by an appropriate method.

[0031] (3) Sample 3: 500 g of dried Periplaneta americana worms were taken, crushed, and steam smelted to extract the oil of Periplaneta americana, which was refined by an appropriate method to obtain Extract 3. Experiments show that the stretch-promoting repair material prepared by the invention has strong repair effect, good stabi...

Embodiment 2

[0033] Embodiment 2 The preparation of Periplaneta americana oil injection of the present invention

[0034] [Prescription] Raw materials: Periplaneta americana oil 800-3000mg; excipients: sodium chloride 5g, polysorbate-805g; add water for injection to 1000ml.

[0035] [Preparation method] Take Periplaneta americana oil, add sodium chloride and polysorbate-80, mix well, add water for injection to 1000ml, filter, seal in a 2ml ampoule, and sterilize for 30 minutes.

Embodiment 3

[0036] Embodiment 3 The preparation of Periplaneta americana oil soft capsule of the present invention

[0037] [Prescription] Raw materials: Periplaneta americana oil 800-3000mg; excipients: soybean oil 600g; made into 1000 soft capsules.

[0038] 【Preparation method】Take Periplaneta americana fat, add soybean oil, mix well, press into 1000 soft capsules, transfer to a cage to shape, wash the pills, and dry to obtain.

[0039] The beneficial effects of the present invention will be specifically described below through test examples.

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Abstract

The invention provides an application of American cockroach lipid in tumor prevention. Researches reveal that the American cockroach lipid can be used for effectively inhibiting the growth of tumor cells of a breast cancer, a rectal cancer, a liver cancer and the like, is good in antineoplastic activity and provides a new choice for clinical medication.

Description

technical field [0001] The present invention relates to oil of Periplaneta americana and its preparation method and application. Background technique [0002] According to the statistics of the World Health Organization (WHO), 10 million people in the world suffer from cancer every year, and the number of people who die from cancer accounts for 12% of the global death toll. There are 1.8 million new cancer patients and 1.4 million deaths every year in our country, and the incidence of cancer in our country shows a sharp upward trend. In the past less than 20 years, the incidence of cancer in my country has increased by 69%, and the death rate has increased by 29.4%. Therefore, cancer is seriously threatening the health of the people of the world and the Chinese people. The treatment of tumors with traditional Chinese medicine is a major feature of China in the field of tumor treatment, and it has received more and more attention. However, it is rare to see Chinese patent ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61K9/08A61K9/48A61P35/00
CPCA61K9/08A61K9/0019A61K9/4858A61K2236/33A61K2236/333A61K2236/35A61K2236/37A61K2236/51
Inventor 苏柘僮熊永爱邹俊波
Owner SICHUAN GOODDOCTOR PANXI PHARMA
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