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Production process of CIT capsule demoulding agent

A production process and release agent technology, which is applied in the production process of CIT capsule release agent, can solve the problems of reducing the transparency and smoothness of the capsule, poor demoulding, and cracking on the surface of the capsule, so as to improve efficiency and thermal stability. , easy demoulding, good molding stability

Active Publication Date: 2015-03-11
ANHUI HUASHENG TECH HLDG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the technical problems existing in the background technology, the present invention proposes a production process of a CIT capsule mold release agent. The mold release agent in the production process can effectively solve the cracks on the surface of the capsule body caused by poor mold release and reduce the capsule's durability. Issues such as transparency and finish

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0035] The embodiment of the present invention proposes a process for producing a capsule release agent. The raw materials of the capsule release agent in parts by weight include: 63 parts of No. 65 microcrystalline paraffin, 140 parts of zinc stearate, 130 parts of stearic acid, and soy eggs 50 parts of phospholipids, 20 parts of n-decyl alcohol, 54 parts of linseed oil, 5 parts of glycerin, 12 parts of lubricating silicone grease;

[0036] According to the aforementioned raw material ratio, the production process of the CIT capsule release agent includes the following process steps:

[0037] S1. Add linseed oil into the first reaction vessel, add lubricating silicone grease, glycerin, and n-decyl alcohol in sequence under stirring conditions, slowly warm up to 50°C and stir for 3.5 hours;

[0038] S2. Put No. 65 microcrystalline paraffin wax into a 200L stainless steel reactor, heat the paraffin wax with steam heating to 65°C, start stirring when the wax melts and become liquid, sl...

Embodiment 2

[0042] According to an embodiment of the present invention, a production process for a capsule release agent is proposed. The raw materials of the capsule release agent in parts by weight include: 72 parts of No. 75 microcrystalline paraffin, 120 parts of zinc stearate, 120 parts of stearic acid, and soy eggs. 60 parts of phospholipids, 5 parts of lauryl alcohol, 40 parts of soybean oil, 10 parts of glycerin, 18 parts of lubricating silicone grease;

[0043] According to the aforementioned raw material ratio, the production process of the CIT capsule release agent includes the following process steps:

[0044] S1. Add soybean oil to the first reaction kettle, add lubricating silicone grease, glycerin, and lauryl alcohol in sequence under stirring conditions, slowly heat to 60°C and stir for 2.5 hours;

[0045] S2. Add No. 75 microcrystalline paraffin to a 200L stainless steel reactor, heat the paraffin with steam heating to 75°C, start stirring when the paraffin melts to a liquid sta...

Embodiment 3

[0049] According to an embodiment of the present invention, a production process for a capsule release agent is proposed. The raw materials of the capsule release agent in parts by weight include: 72 parts of No. 70 microcrystalline paraffin, 136 parts of zinc stearate, 125 parts of stearic acid, and soy eggs 56 parts of phospholipids, 12 parts of n-octanol, 47 parts of corn oil, 8 parts of glycerin, 15 parts of lubricating silicone grease;

[0050] According to the aforementioned raw material ratio, the production process of the CIT capsule release agent includes the following process steps:

[0051] S1. Add corn oil to the first reaction kettle, add lubricating silicone grease, glycerin, and n-octanol in sequence under stirring conditions, slowly heat to 58°C, and stir for 3 hours;

[0052] S2. Put No. 70 microcrystalline paraffin wax into a 200L stainless steel reactor, heat the paraffin wax with steam heating to 70°C, start stirring when the wax melts to a liquid state, slowly ad...

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Abstract

The invention discloses a production process of a CIT capsule demoulding agent. The capsule demoulding agent comprises the following raw materials by weight: 63-72 portions of paraffin wax, 120-140 portions of zinc stearate, 120-130 portions of stearic acid, 50-60 portions of soybean lecithin, 5-20 portions of fatty alcohol, 40-54 portions of vegetable oil, 5-10 portions of glycerin and 12-18 portions of silicone grease. The production process is as below: first heating and evenly mixing vegetable oil, silicone grease, glycerol and fatty alcohol; then adding the mixture into a reactor containing molten paraffin wax; sequentially adding zinc stearate, stearic acid and soy lecithin, preserving, stirring and filtering; cooling the filtrate to obtain the capsule demoulding agent. The production process of CIT capsule demoulding agent provided by the invention has the advantages of easily available raw materials, simple process, convenient operation and easiness for scale production. The produced demoulding agent in improving the qualified rate of products has good effects in improve transparency and smoothness of the capsule.

Description

Technical field [0001] The invention relates to the technical field of release agents, in particular to a production process of a CIT capsule release agent. Background technique [0002] In the pharmaceutical and health care products industry, capsules are widely used as a shell to protect medicines. Drugs in capsules are generally powders or granules that are irritating to the esophagus and gastric mucosa, or have a bad taste, are easy to volatilize, are easily broken down by saliva in the mouth, and are easily inhaled into the trachea. If these drugs are packed The capsule not only protects the properties of the drug from being destroyed, but also protects the digestive organs and respiratory tract. Removing the capsule shell may result in loss of medicine, waste of medicine, and reduced efficacy. In the production process of these capsules, especially the production process of hollow capsules, the release agent is one of the important components and is essential. [0003] The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C10M169/04C10M177/00
Inventor 盛义良
Owner ANHUI HUASHENG TECH HLDG
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