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Traditional Chinese medicine capable of benefiting qi, activating blood circulation, softening hardness, dissipating stagnation, realizing detoxification and relieving pain as well as preparation method thereof

A technology of softening hard masses, replenishing qi and activating blood circulation, applied in the traditional Chinese medicine for detoxification and relieving pain and its preparation, softening hard masses, replenishing qi and activating blood circulation, it can solve the problems of inconvenient taking for patients, increase patient pain, large dosage, etc., and achieve medication compliance High, excellent curative effect, the effect of taking less dosage

Inactive Publication Date: 2015-02-18
武汉科德中医医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, most of the tumor traditional Chinese medicines currently used clinically have the disadvantages of inaccurate curative effect, large side effects, etc., and the dosage is large, and the dosage forms are mostly plaster pills or decoctions, which is inconvenient for patients to take, especially for patients with digestive tract tumors Taking these drugs in large doses further increases the suffering of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A traditional Chinese medicine for invigorating qi and activating blood circulation, softening and resolving hard masses, detoxifying and relieving pain, which is made from the following raw materials:

[0030] Panax notoginseng 4Kg, American ginseng 2Kg, Hedyotis diffusa 10Kg, Banzhilian 10Kg, Radix Paeoniae Alba 8Kg, Angelica 4Kg, Prunella vulgaris 10Kg, Bupleurum 4Kg, Citrus aurantium 4Kg, Licorice 4Kg.

[0031] The preparation method is:

[0032] 1) American ginseng and Panax notoginseng are pulverized into a fine powder with a particle size of 120 mesh (referring to fine powder that can pass through a 120 mesh sieve);

[0033] 2) Add Hedyotis diffusa and Scutellaria barbata with 5 times (weight) 60% ethanol for reflux extraction twice, combine the ethanol extracts, recover ethanol and condense it into a thick paste with a relative density of 1.3-1.35;

[0034] 3) Extract the volatile oil of Bupleurum, Citrus aurantii, and Angelica with steam distillation, decoct t...

Embodiment 2

[0075] Embodiment 2 clinical trials

[0076] 1. General information: A total of 53 patients, including 29 males and 24 females, aged between 28 and 56.

[0077] 2. Medication method: Take the capsules of Example 1, 3 times a day, 5 capsules each time, 30 days as a course of treatment.

[0078] 3. Criteria for judging curative effect:

[0079] Significant effect: cancer cells are reduced, tumors are shrunk by more than 50%, immunity is improved, energy is full, and there is no pain;

[0080] Effective: cancer cells are basically inhibited, tumors shrink by more than 30%, immunity is improved, mental health is poor, and pain is relieved;

[0081] Invalid: The cancer cells remain unchanged, the mental state is poor, there is still pain, and the symptoms are obvious.

[0082] 4. Treatment results (the observation period is 3 months):

[0083] Table 3 Clinical trial results

[0084]

[0085] The traditional Chinese medicine preparation of the present invention can ...

Embodiment 3

[0086] Embodiment 3 acute toxicity test

[0087] 1. Purpose of the experiment

[0088] 1. LD 50 Determination: Observe the toxic reaction and death situation after the capsule of Example 1 is given to animals once.

[0089] 2. MTD determination: When the toxicity of the test substance is low, LD cannot be detected 50 When the drug is used, the maximum tolerated dose can be determined once or a day, and it can also reflect the toxicity of the drug.

[0090] 2. Experimental materials

[0091] 1. 40 clean-grade Kunming mice, weighing 19-21 g, half male and half male, were provided by Hubei Experimental Animal Research Center, animal license number SCXK (Hubei) 2008-0005. The experimental animals were kept in plastic feeding boxes, and the feed was full-price pure pellet feed provided by the Hubei Experimental Animal Research Center, and the drinking water was clean tap water.

[0092] The laboratory temperature is 19-21°C and the relative humidity is 40-60%.

[0093] 2. Dru...

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Abstract

The invention discloses a traditional Chinese medicine capable of benefiting qi, activating blood circulation, softening hardness, dissipating stagnation, realizing detoxification and relieving pain. The traditional Chinese medicine is prepared from raw materials in parts by weight as follows: 2-6 parts of pseudo-ginseng, 1-4 parts of American ginseng, 5-15 parts of spreading hedyotis herb, 5-15 parts of barbed skullcap herb, 5-10 parts of white peony roots, 2-6 parts of Chinese angelica, 5-15 parts of common selfheal fruit-spike, 2-6 parts of Chinese thorowax roots, 2-6 parts of fructus aurantii and 2-6 parts of liquorice roots. The invention further discloses a preparation method of the traditional Chinese medicine. The traditional Chinese medicine has functions of benefiting the qi, activating the blood circulation, softening the hardness, dissipating the stagnation, realizing detoxification and relieving the pain and can control the growth of tumors and obviously improve clinical symptoms of tumor patients, total effective rates are higher than 65% for treatment of lung cancer, liver cancer, esophageal cancer, breast cancer and gastric cancer, besides, the traditional Chinese medicine also has the characteristics of small taking dosage, convenience in taking, storage and carrying, high compliance and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine for replenishing qi and activating blood circulation, softening and resolving hard masses, detoxifying and relieving pain and a preparation method thereof. Background technique [0002] In the past 20 years in my country, tumors have shown a trend of younger age and higher morbidity and mortality in the "third line". The "2012 China Cancer Registration Annual Report" shows that there are about 3.12 million new cancer cases each year, an average of 8,550 people per day, and 6 people are diagnosed with cancer every minute in the country. The national cancer mortality rate is 1.8054 / 100,000, with 2.7 million deaths due to cancer every year. The probability of death due to cancer among Chinese residents is 13%, that is, 1 out of every 7 to 8 people dies from cancer. The tumor mortality rate of men was higher than that of women,...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P29/00A61P37/04A61P35/00A61P35/04
CPCA61K36/232A61K36/233A61K36/258A61K36/484A61K36/536A61K36/539A61K36/71A61K36/748A61K36/752A61K2236/15A61K2236/331A61K2236/39A61K2236/55A61K2300/00
Inventor 张德忠陈树和刘胡丹刘焱文易灿玲张琦
Owner 武汉科德中医医院有限公司
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