Traditional Chinese medicine prescription for preventing and treating radiation-induced oral mucositis and production method of traditional Chinese medicine prescription

A technology for oral mucositis and a production method, which can be applied to pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, etc., can solve the problems of ineffective prevention and protection of deep mucosal damage, poor efficacy, and weak tissue penetration. , to achieve the effect of reducing economic burden, no pollution, and simple production process

Active Publication Date: 2015-01-28
贵港市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, topical medications are mostly used for oral mucosal damage caused by radiotherapy. Dolby's solution and watermelon cream are commonly used in clinical practice. Their functions are mainly to inhibit the growth of bacteria and promote the repair of damage. The preventive and protective effect is not great, and the curative effect is poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Take 15 parts of Astragalus, 5 parts of Ligustrum lucidum, 25 parts of Hedyotis heterophylla, 10 parts of Hedyotis diffusa, 7 parts of Asparagus, 7 parts of Rehmannia glutinosa, 5 parts of Dendrobium, 5 parts of capillary, 25 parts of reed root, and 10 parts of Salvia , 5 parts of ginseng, 5 parts of burdock, 5 parts of skullcap, 7 parts of platycodon, 1 part of roasted licorice, and fry in casserole or enamel vessel. Soak in cold water for about 20 minutes before frying. The amount of water should be soaked in 1-3cm of the medicinal surface, boiled with strong fire, then decocted with low heat for 20-30 minutes, one dose per day, each dose of traditional Chinese medicine is decocted twice, and a total of about 400ml of medicine should be decocted, mixed well and taken in the morning and evening. .

Embodiment 2

[0040] Take 20 parts of Astragalus, 10 parts of Ligustrum lucidum, 30 parts of Hedyotis heterophylla, 15 parts of Hedyotis diffusa, 12 parts of Asparagus, 12 parts of Rehmannia glutinosa, 10 parts of Dendrobium, 10 parts of capillary root, 30 parts of reed root, and 15 parts of Salvia miltiorrhiza , 10 parts of ginseng, 10 parts of burdock, 10 parts of skullcap, 12 parts of platycodon, 6 parts of roasted licorice and 15 herbs, decoct in a casserole or enamel vessel, soak in cold water for about 20 minutes before frying, and use for decocting The amount of water should be soaked in 1-3cm of the medicinal surface, boiled with strong fire, then decocted with low heat for 20-30 minutes, one dose per day, each dose of traditional Chinese medicine is decocted twice, and a total of about 400ml of medicine should be decocted, mixed well and taken in the morning and evening. .

Embodiment 3

[0042] Take 25 parts of Astragalus, 15 parts of Ligustrum lucidum, 35 parts of Hedyotis heterophylla, 20 parts of Hedyotis diffusa, 17 parts of Asparagus, 17 parts of Rehmannia glutinosa, 15 parts of Dendrobium, 15 parts of capillary, 35 parts of reed root, and 20 parts of Salvia miltiorrhiza , 15 parts of ginseng, 15 parts of burdock, 15 parts of skullcap, 17 parts of bellflower, 11 parts of roasted licorice. Fifteen herbs are used for decocting in a casserole or enamel vessel. Soak in cold water for about 20 minutes before frying. The amount of water should be soaked in 1-3cm of the medicinal surface, boiled with strong fire, then decocted with low heat for 20-30 minutes, one dose per day, each dose of traditional Chinese medicine is decocted twice, and a total of about 400ml of medicine should be decocted, mixed well and taken in the morning and evening. .

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PUM

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Abstract

The invention discloses a traditional Chinese medicine prescription for preventing and treating radiation-induced oral mucositis. The traditional Chinese medicine prescription is produced from the following raw materials in parts by weight: astragalus membranaceus, glossy privet fruit, radix pseudostellariae, oldenlandia diffusa, asparagus fern, dried rehamnnia root, dendrobe, oriental wormwood, rhizoma phragmitis, salvia miltiorrhiza, radix scrophulariae, burdock, scutellaria baicalensis, platycodon grandiflorum and fried licorice root. Clinical verifications indicate that the traditional Chinese medicine has an obvious treatment effect on the radiation-induced oral mucositis caused by the radiotherapy of head and neck tumors, and is exact in clinical efficacy, safe and free from toxic and side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine and a preparation method thereof, in particular to a traditional Chinese medicine prescription for preventing and treating radioactive oral mucositis and a preparation method thereof. Background technique [0002] Radiotherapy is one of the important treatment methods for head and neck cancer. Oral mucositis of varying degrees occurs in most patients receiving radiation therapy to the head and neck. Oral mucositis is defined as inflammation and ulceration of the oral mucosa with pseudomembrane formation. Oral mucositis not only causes pain, difficulty in eating, weight loss, easy concurrent infection, increased economic burden and other consequences to patients, but also affects the smooth progress of the treatment process in severe cases, and even threatens life. [0003] How to find an effective method to further improve the curative effect and reduce the adverse reactions of radiotherapy has ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P1/02
CPCA61K9/0095A61K36/28A61K36/34A61K36/36A61K36/481A61K36/484A61K36/537A61K36/539A61K36/638A61K36/748A61K36/804A61K36/808A61K36/8965A61K36/8984A61K36/899A61K2236/331A61K2236/51A61K2300/00
Inventor 蔡凯胡联民谭长超陈刚
Owner 贵港市中医医院
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