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Traditional Chinese medicine composition for treating blood-deficiency Yang-floating type insomnia and preparation method thereof

A technology for insomnia and composition, which is applied in the field of traditional Chinese medicine composition for treating insomnia with blood deficiency and yang floating syndrome and its preparation field, which can solve the problems of insomnia without treating blood deficiency and yang floating syndrome, and achieve the effect of improving clinical treatment effect

Inactive Publication Date: 2015-01-14
XIUZHENG PHARMA GRP CHANGCHUN HIGH NEW PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many Chinese patent medicines for treating insomnia in the market now, but there is no traditional Chinese medicine for treating blood deficiency and yang floating type insomnia

Method used

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  • Traditional Chinese medicine composition for treating blood-deficiency Yang-floating type insomnia and preparation method thereof
  • Traditional Chinese medicine composition for treating blood-deficiency Yang-floating type insomnia and preparation method thereof
  • Traditional Chinese medicine composition for treating blood-deficiency Yang-floating type insomnia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] 30 parts of Suanzaoren, 6 parts of Boziren, 6 parts of Schisandra, 12 parts of keel, 12 parts of oyster, 6 parts of mother of pearl, 6 parts of Anemarrhena, 6 parts of Chuanxiong, 12 parts of Poria cocos, 4 parts of licorice. The aforementioned raw materials are pulverized into coarse powder of 10-20 mesh.

[0021] The volatile oils of Chuanxiong, Suanzaoren and Baiziren are extracted by carbon dioxide supercritical fluid extraction. The extraction conditions are: temperature 25-30°C, pressure 5-15MPa, time 2 hours, to obtain a mixture of volatile oils.

[0022] The above-mentioned volatile oil mixture is clathrated by clathrate technology to obtain clathrate volatile oil.

[0023] Add mother-of-pearl, keel, and oyster coarse powder to 13 times the water with a pH value of 2, and use a high-voltage pulse-semi-bionic extraction device to extract, with a field strength of 4000-15000, pulses of 1500-10000, a temperature of 30°C, and a processing time of 1-5 milliseconds, ...

Embodiment 2

[0026] 28 parts of Suanzaoren, 5 parts of Boziren, 5 parts of Schisandra, 11 parts of keel, 11 parts of oyster, 5 parts of mother-of-pearl, 5 parts of Anemarrhena, 5 parts of Chuanxiong, 11 parts of Poria cocos, and 3 parts of licorice. The powder prepared according to the preparation method of Example 1 is added with appropriate amount of starch and dextrin, mixed evenly, granulated, dried, and packed into capsules.

Embodiment 3

[0028] 25 parts of Suanzaoren, 4 parts of Boziren, 4 parts of Schisandra, 10 parts of keel, 10 parts of oyster, 4 parts of mother of pearl, 4 parts of Anemarrhena, 4 parts of Chuanxiong, 10 parts of Poria cocos, 2 parts of licorice. The powder prepared by the preparation method in Example 1 is added with an appropriate amount of sucrose and dextrin, mixed uniformly, made into granules, dried, and obtained.

[0029] Drug efficacy verification

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Abstract

The invention discloses a traditional Chinese medicine composition for treating blood-deficiency Yang-floating type insomnia and a preparation method thereof. The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 25-30 parts of spina date seed, 4-6 parts of seman platycladi, 4-6 parts of Chinese magnoliavine fruit, 10-12 parts of os draconis, 10-12 parts of oyster, 4-6 parts of mother of pearl, 4-6 parts of rhizoma anemarrhenae, 4-6 parts of ligusticum chuanxiong, 10-12 parts of poria cocos, and 2-4 parts of licorice. The preparation method comprises the steps: smashing the raw materials into coarse powders; extracting volatile oil from ligusticum chuanxiong, spina date seed and seman platycladi, carrying out inclusion on the volatile oil, taking the coarse powders of mother of pearl, os draconis and oyster, carrying out voltage pulse-semi bionic extraction, and extracting the ligusticum chuanxiong, spina date seed and seman platycladi drug dregs having the volatile oil extracted and rhizoma anemarrhenae, liquorice, poria cocos and Chinese magnoliavine fruit by a high-voltage pulse extraction device; concentrating the extract liquid into a thick paste; mixing the volatile oil and the thick paste to obtain the composition. The traditional Chinese medicine composition has the beneficial effects that the traditional Chinese medicine composition achieves the purpose of radical treatment on insomnia, and neither has western medicine's shortcomings not causes iatrogenic diseases. Through the use of the preparation method combining the supercritical carbon dioxide fluid extraction method with high-voltage pulse-semi bionic extraction, the medicine clinical curative effect is improved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating insomnia with blood deficiency and yang floating syndrome and a preparation method thereof. Background technique [0002] Insomnia belongs to the categories of "insomnia" and "not sleeping" in traditional Chinese medicine, and can appear in different syndromes of various diseases. With the rapid development of society, the acceleration of the pace of life, the increase of work pressure, people's spirits are in a state of tension, leading to more and more patients with insomnia, and the incidence rate continues to rise. Foreign epidemiological surveys show that, About 33% of people experience sleep disturbance every year, and about 17% suffer from severe insomnia. Insomnia has seriously affected people's life, work and physical and mental health. Therefore, there is a large market for drugs to treat ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P25/20A61K35/02A61K35/56
CPCA61K36/725A61K9/0053A61K9/1652A61K9/2059A61K9/4866A61K35/02A61K35/618A61K36/076A61K36/14A61K36/236A61K36/484A61K36/57A61K36/79A61K36/8964A61K2236/15A61K2236/37A61K2236/51A61K2300/00
Inventor 展月吴巧玲关丽丹
Owner XIUZHENG PHARMA GRP CHANGCHUN HIGH NEW PHARMA CO LTD
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