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Traditional Chinese medicine composition for treating gout and hyperuricemia and preparation method thereof

A technology of hyperuricemia and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of gout and hyperuricemia, which can solve the problems of recurrence of arthritis swelling and pain, aggravation of gout, weight gain, etc., and prevent the disease Recurrence and prevention of joint deformation

Active Publication Date: 2014-10-01
刘鸿生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, neither of the two drugs can be used during the acute attack of gout, otherwise it will aggravate the gout and even re-emerge or worsen the relieved arthritis swelling and pain
[0003] The uric acid metabolizing enzyme KIYSTXX2 newly approved by the US FDA can metabolize uric acid into harmless substances and excrete it through urine to reduce the level of uric acid in gout patients. The effect is certain, but the risk of allergic reactions in clinical practice is relatively high, especially nausea , vomiting, chest pain, constipation, nasal irritation and other side effects may bring great pain to patients

Method used

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  • Traditional Chinese medicine composition for treating gout and hyperuricemia and preparation method thereof
  • Traditional Chinese medicine composition for treating gout and hyperuricemia and preparation method thereof
  • Traditional Chinese medicine composition for treating gout and hyperuricemia and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Chinese medicine composition ingredients:

[0038] The traditional Chinese medicine composition is composed of the following ingredients and weight ratio: 30 grams of Qinpi, 12 grams of black plum, 15 grams of honeysuckle, 15 grams of Smilax, 12 grams of Desmodium, 12 grams of Plantain, 15 grams of Polygonum cuspidatum, 15 grams of raw barley, Atractylodes macrocephala 9 grams, 15 grams of pangolin, 12 grams of clematis, 10 grams of grape seeds, 10 grams of fennel, 10 grams of lily, 15 grams of stone see wear, 20 grams of raw oysters.

[0039] The preparation method of Chinese medicine composition:

[0040] 1) The above compositions are mixed in proportion, rinsed twice with water to remove residues such as ash, pesticides, fertilizers, lead, arsenic and mercury;

[0041] 2) Soak in warm water for 0.5h, extract twice at 100°C, the amount of water used is 10 times and 8 times the mass of the composition respectively, combine the extracts, concentrate until equal to the ma...

Embodiment 2

[0044] Chinese medicine composition ingredients:

[0045] The traditional Chinese medicine composition is composed of the following ingredients and weight ratio: 30 grams of Qinpi, 12 grams of black plum, 15 grams of honeysuckle, 15 grams of Smilax, 12 grams of Desmodium, 12 grams of Plantain, 15 grams of Polygonum cuspidatum, 15 grams of raw barley, Atractylodes macrocephala 9 grams, 15 grams of pangolin, 12 grams of clematis, 10 grams of grape seeds, 10 grams of fennel, 10 grams of lily, 15 grams of stone see wear, 20 grams of raw oysters.

[0046] The preparation method of Chinese medicine composition:

[0047] 1) The above compositions are mixed in proportion, rinsed twice with water to remove residues such as ash, pesticides, fertilizers, lead, arsenic and mercury;

[0048] 2) Soak in warm water for 1.5 hours, extract 5 times with 50% ethanol at 60°C, the amount of ethanol used each time is 5 times the mass of the composition, combine the extracts, concentrate until the ...

Embodiment 3

[0052] Chinese medicine composition ingredients:

[0053] The traditional Chinese medicine composition is composed of the following ingredients and weight ratios: 20 grams of Qinpi, 5 grams of black plum, 5 grams of honeysuckle, 5 grams of Smilax, 5 grams of Desmodium, 5 grams of Plantain, 5 grams of Polygonum cuspidatum, 5 grams of raw barley, and 5 grams of Atractylodes macrocephala. 5 grams, 5 grams of pangolin, 5 grams of clematis, 20 grams of grape seeds, 20 grams of fennel, 20 grams of lily, 25 grams of Iwami, 30 grams of raw oysters.

[0054] The preparation method of Chinese medicine composition:

[0055] 1) The above compositions are mixed in proportion, rinsed twice with water to remove residues such as ash, pesticides, fertilizers, lead, arsenic and mercury;

[0056] 2) Soak in warm water for 1 hour, extract 3 times with 30% methanol solvent at 70 ° C, the amount of methanol used is 7 times the mass of the composition, combine the extracts, concentrate to equal the...

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Abstract

The invention belongs to the technical field of pharmaceutical manufacturing and particularly relates to a traditional Chinese medicine composition for treating gout and hyperuricemia and a preparation method thereof. The traditional Chinese medicine composition consists of the following herbs: 20-40 g of ash bark, 5-20 g of dark plum, 5-25 g of honeysuckle stem, 5-25 g of glabrous greenbrier rhizome, 5-20 g of longhairy antenoron herb, 5-20 g of plantain, 5-20 g of giant knotweed, 5-20 g of raw coix seed, 5-20 g of atractylodes macrocephala, 5-25 g of rhizoma dioscoreae nipponicae, 5-25 g of clematis root, 5-20 g of grape seed, 5-20 g of rhizoma dioscoreae hypoglaucae, 5-20 g of lily, 5-25 g of salvia chinensis and 10-30 g of raw oyster shell. The traditional Chinese medicine composition provided by the invention consists of 10 herbs, and is mainly used for treating and relieving hyperuricemia caused by various reasons and various complications caused by hyperuricemia, including normal rise of blood urea and pain, swelling, erythema, stiffness, pyrexia and the like of joints.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a traditional Chinese medicine composition for treating gout and hyperuricemia and a preparation method thereof. Background technique [0002] Gout is a disease with increased blood uric acid caused by purine metabolism disorder or uric acid excretion disorder. This disease is lingering and difficult to heal, and recurrent outbreaks bring great misery to middle-aged and elderly patients. Its symptoms are intermittent joint swelling, redness, heat, pain and joint stiffness, and severe cases are bedridden or even disabled. Allopurinol and probenecid are drugs for gout remission. However, neither of the two drugs can be used during the acute attack of gout, otherwise the gout will be aggravated, and even the pain of arthritis that has been relieved will relapse or become heavier. [0003] The uric acid metabolizing enzyme KIYSTXX2 newly approved by the US FDA can met...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K36/90A61P19/06A61K35/56
Inventor 刘鸿生伊原
Owner 刘鸿生
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