Nutritional composition for improving intestinal flora

A nutritional composition and application technology, applied in the field of nutritional composition for improving intestinal flora, can solve problems such as poor intestinal flora, achieve safe intake, and improve the effect of intestinal flora

Active Publication Date: 2016-05-25
MEIJI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, it is considered that the number of bacteria of the genus Bifidobacterium in the intestinal tract of patients undergoing enteral nutrition is less than that of normal people (Non-Patent Document 2, Non-Patent Document 3), and the intestinal flora is worse than that of normal people

Method used

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  • Nutritional composition for improving intestinal flora
  • Nutritional composition for improving intestinal flora
  • Nutritional composition for improving intestinal flora

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0053] In the preparation method of protein hydrolysate, the five parameters for optimization include preheating, enzyme to substrate ratio (E / S), pH, hydrolysis temperature, and hydrolysis time. For example, the following conditions can be cited . That is, preheating: 65 to 90°C, E / S: 0.01 to 0.2, pH: 2 to 10, hydrolysis temperature: 30 to 65°C, and hydrolysis time: 3 to 20 hours.

[0054] Examples of enzymes used for proteolysis include the following enzymes. The following enzymes can be obtained from suppliers such as NovoNordisk.

[0055] 1) Endo-type protease

[0056] ·From Bacillus licheniformis: Alcalase

[0057] ·From B.lentus: Esperase

[0058] ·From Bacillus subtilis: Neutrase

[0059] ·From bacteria: complex protease (Protamex)

[0060] ·From porcine pancreas: PTN (trypsin)

[0061] 2) Exo-type protease

[0062] ·From Aspergillusoryzae: Flavourzyme

[0063] ·From pig or bovine offal: Carboxypeptidase

[0064] In addition to the above-mentioned enzymes, animal-derived pancreatin,...

Embodiment 1

[0126] [Example 1: Effectiveness test using animals]

[0127] (Tested sample)

[0128] Prepare the ordinary liquid foods and the nutritional composition of the present invention as shown in Tables 3 and 4, and freeze the obtained materials by retort (heat and pressure) sterilization (135~145℃×5~10 seconds) Dry it as the test sample. Among them, the content of oleic acid contained in the nutritional composition in the table is 39% of the fatty acid composition.

[0129] Control group: Ingested freeze-dried products of ordinary liquid food.

[0130] Test group: A freeze-dried product of the nutritional composition of the present invention was taken.

[0131] table 3

[0132]

[0133] Table 4

[0134]

[0135] (Animal experiment)

[0136] Using body weight as an indicator, 6-week-old male SD rats (Japanese SLC) were divided into two groups: control group and test group (n=6 in each group), and allowed them to take the test sample freely for 18 days or from the same day (day0) 22 days. Dur...

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PUM

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Abstract

A nutritional composition comprising milk protein hydrolyzate, a cultured milk protein, a phospholipid, an oil containing oleic acid, and isomaltulose, wherein an intestinal flora improvement effect has been found. Specifically, this nutritional composition has been found to increase the bacteria count and occupancy of Bifidobacterium genus and Lactobacillus genus in the intestine, in in vivo tests using rats. From these results, this nutritional composition is understood to promote the propagation of the Bifidobacterium genus and / or the Lactobacillus genus of bacteria.

Description

Technical field [0001] The present invention relates to a nutritional composition for improving intestinal flora. Background technique [0002] The intestinal environment is considered to be related to various diseases and aging. It is said that for the elderly, a decrease in the number of bacteria belonging to the genus Bifidobacteriu can cause disorders of the intestinal flora. Someone pointed out that this deterioration of the intestinal flora may promote aging. Bad bacteria in the intestine can produce harmful spoilage products (ammonia, amines, phenols, indole, etc.). These spoilage products directly damage the intestines and part of them will be absorbed into the body. They not only promote aging during the entire life of the host, but are also related to the onset of diseases such as cancer, myocardial infarction, and hypertension. The benign bacteria such as Bifidobacterium in the intestine can hinder the proliferation of bad bacteria. Therefore, it is suggested that ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23C9/152A23C19/068A23L33/18A23L33/19A23L33/115A23L33/125
CPCA23C19/0765A23L33/18A23L33/19A23V2002/00A61P1/00A61P3/02A23V2200/32A23V2200/3202A23V2250/1842A23V2250/188A23V2250/5424A23V2250/55A23V2250/62A23V2300/28A23V2300/34
Inventor 永渊真也粂久枝山地健人
Owner MEIJI CO LTD
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