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Hydrogel eye protective pad dressing and preparation method thereof

The technology of hydrogel and eye patch is applied in the field of medical wound dressing and its preparation, which can solve the problems of poor adhesion between the sample and the eye, weak sticking, poor adhesion, etc., so as to shorten the preparation period and simplify the preparation method. , the effect of not easy to fall off

Active Publication Date: 2014-07-02
SAIKE SAISI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The eye protection stickers described in the above two patents can effectively solve the problems of poor adhesion, no outer protective layer and support layer, poor mechanical properties, and inconvenient operation; but the above two design methods are the most common designs, and there are samples Disadvantages of poor adhesion to the eyes and weak adhesion

Method used

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  • Hydrogel eye protective pad dressing and preparation method thereof
  • Hydrogel eye protective pad dressing and preparation method thereof
  • Hydrogel eye protective pad dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-10

[0045] Embodiment 1-10, preparation of hydrogel eye protection patch dressing

[0046] Embodiment 1-10 hydrogel eye protection patch dressing of the present invention and the gel layer formula of comparative example are as shown in table 1-2

[0047] Table 1 Embodiment 1-5 hydrogel eye protection patch dressing and the gel layer formula of Comparative Example 1

[0048] (grams of each component per 1000g hydrogel)

[0049]

[0050] Table 2 Embodiment 6-10 hydrogel eye protection patch dressing and the gel layer formula of comparative example 2

[0051] (grams of each component per 1000g hydrogel)

[0052]

[0053] Test 1. Product performance parameter detection

[0054] The performance parameters of the hydrogel eye protection patch dressing prepared in embodiment 1-10 are detected, and the product of embodiment 1-10 meets the following requirements:

[0055] 1. Appearance: It is a colorless or slightly milky white transparent gel.

[0056] 2, water content: ...

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Abstract

The invention discloses a hydrogel eye protective pad dressing and a preparation method thereof. The hydrogel eye protective pad dressing is sequentially composed of an adhesion layer, a strengthening layer, a gel layer and an isolating layer. The shape of the adhesion layer is specially designed so that the adhesion layer is more consistent with an ergonomics principle. The hydrogel eye protective pad dressing contains the following components in percentage by mass: 2-15% of water-soluble high molecular polymer, 0.1-5% of pseudoplastic high molecular polymer, 0.1-10% of humectant and the balance of water, totaling 100%. The various components are integrated by virtue of a series of processes; the dressing is prepared by pouring a solution into a die, and implementing irradiation sterilization after curing the solution. Through detection on product performance, a result of a moisturizing effect test shows that the dressing disclosed by the invention is good in biocompatibility, and free from sensitization, irritation as well as toxic and side effect; moreover, the dressing is good in moisture retention and capable of keeping the humidity above 90% for at least 8 hours, and is suitable for popularization and application in a large area.

Description

technical field [0001] The invention belongs to the field of medical wound dressing and its preparation, and in particular relates to a hydrogel suitable for sticking the outside of the eye of a patient undergoing general anesthesia or deep coma, providing the patient with a relatively closed humid environment, and preventing exposure keratitis Eye protection patch dressing and preparation method thereof. Background technique [0002] Exposure keratitis refers to corneal inflammation in which the cornea loses the protection of the eyelids and is exposed to the air, causing dryness, epithelial shedding and secondary infection, and severe cases can lead to corneal ulcers. The specific manifestations are photophobia, tearing, foreign body sensation and blurred vision in the eyes, which bring a certain degree of pain to the patient. Studies have shown that exposure keratitis occurs in 70% of patients under general anesthesia as high as 40% to 60%. Therefore, adequate attention ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/42A61K47/36A61P27/02C08J3/28A61L2/08
Inventor 徐艳丽黄琳静刘常琳孙春明宋万学
Owner SAIKE SAISI BIOTECH CO LTD
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