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Method for assessing lipid metabolism type obese gene constitution

An obesity gene and lipid metabolism technology, applied in the field of molecular biology, can solve problems such as high gamma activity, fat accumulation, and increased fatty acid absorption

Inactive Publication Date: 2014-06-04
上海中和堂门诊部有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Mutation or abnormal expression of PPARG can cause high activity of peroxisome proliferator-activated receptor gamma, increase fatty acid absorption, and easily cause fat accumulation

Method used

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  • Method for assessing lipid metabolism type obese gene constitution
  • Method for assessing lipid metabolism type obese gene constitution
  • Method for assessing lipid metabolism type obese gene constitution

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Embodiment Construction

[0129] The purpose of the present invention is to provide a method for assessing the genetic constitution of lipid-metabolizing obesity, which allows the examinee to understand his own genetic constitution and the cause of the individual's obesity potential before considering diet and exercise. Appropriate individualized nutrition and exercise slimming methods will break down the expression patterns of various obesity genes one by one to achieve the most effective and healthy weight loss effect.

[0130] In order to achieve the above purpose, the present invention provides a method for assessing the body constitution of lipid-metabolizing obesity genes. The specific steps are:

[0131] Step 1: Types of samples tested and sampling methods

[0132] Use a sampling swab to swab the left and right cheeks in the mouth at least 40 times up and down to ensure that sufficient cell samples are collected;

[0133] Step 2: Extraction method of genomic DNA

[0134] The genomic DNA of ea...

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Abstract

The invention discloses a method for assessing a lipid metabolism type obese gene constitution. The method is characterized in that SNPs (Single Nucleotide Polymorphisms) site gene genotype of ABCA1 (ATP binding cassette transporter A1) gene, LPL (Lipoprotein Lipase) gene, PPARG (Peroxisome Proliferator-Activated Receptor Gamma) gene, and ADRB3 (beta 3-Adrenergic receptor) gene of individuals are detected and analyzed at the same time so as to provide assessment on lipid metabolism type obese gene constitution for all detected people. According to the method, the detected people can know own gene constitution condition and understand the fat potential causes before slimming by diet and sports, so as to select the optimal individual nutritional and sports slimming modes and break each obese gene expressive form, and as a result, the most effective and healthy weight losing effect can be realized.

Description

technical field [0001] The invention relates to a method for evaluating the genetic constitution of lipid-metabolizing obesity, which can be used for evaluating the genetic constitution of lipid-metabolizing obesity, and specifically prompts subjects to choose different weight-loss strategies according to their genetic constitution, and belongs to the technical field of molecular biology. Background technique [0002] Obesity is a calorie metabolism disorder, where the intake of calories exceeds the calories consumed, resulting in excessive accumulation of body fat. It is generally considered to be obese if it exceeds 20% of the standard weight measured by height. Obesity is a chronic disease closely related to genetic factors and lifestyle. It can cause elevated blood lipids, which can easily lead to fatty liver, arterial vascular disease, heart disease, and diabetes. Obese children can also cause sexual dysfunction and lead to The morbidity and mortality of various diseas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68
CPCC12Q1/6883C12Q1/686C12Q2600/156
Inventor 毛丹丹王校傅咏南李晓莹卞雪莲
Owner 上海中和堂门诊部有限公司
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