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Compound soft capsule containing acanthopanax extract for strengthening brain and preparation method of compound soft capsule

A technique for extracts and soft capsules of Acanthopanax senticosus, which is applied to the field of brain-enhancing compound soft capsules containing the extracts of Acanthopanax senticosus, and the field of preparing the compound soft capsules for strengthening the brains containing the extracts of Acanthopanax senticosus, which can solve the problem of unstable phosphatidylserine. , the effect is not significant, the absorption is limited and other problems, to prevent Alzheimer's disease, health care effect without peculiar smell, improve sleep effect

Active Publication Date: 2014-06-04
侯文阁
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Due to the liver's first-pass effect and the efflux effect of the blood-brain barrier, the human body's absorption of the above three types of health products is limited, so their effects on improving memory and / or improving sleep are not significant
Moreover, phosphatidylserine is unstable (easy to oxidize) and has an odor, and animal brain extracts generally have an odor

Method used

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  • Compound soft capsule containing acanthopanax extract for strengthening brain and preparation method of compound soft capsule
  • Compound soft capsule containing acanthopanax extract for strengthening brain and preparation method of compound soft capsule
  • Compound soft capsule containing acanthopanax extract for strengthening brain and preparation method of compound soft capsule

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preparation example Construction

[0020] The method for preparing the brain-invigorating compound soft capsules containing Acanthopanax extracts provided by the present invention comprises: in an inert atmosphere, sequentially dissolving Acanthopanax extracts, mixed phospholipids and vegetable oils in ethanol liquid of poloxamer, removing Ethanol obtains the content of the soft capsule, and the content is encapsulated in the soft capsule shell, wherein, relative to 100 parts by weight of Araliaceae plant extract, the consumption of mixed phospholipids is 90-240 parts by weight, and the consumption of vegetable oil is 140-300 parts by weight, the amount of poloxamer is 10-50 parts by weight, wherein the mixed phospholipids are composed of animal brain extract and supplementary ingredients, and the weight ratio of animal brain extract and supplementary ingredients is 1: 2-6, and the supplementary ingredients include phosphatidylserine and / or dilinoleoylphosphatidylcholine; the unsaturated fatty acid content in th...

Embodiment 1

[0037] Based on 1000 capsules, take 300mL of medicinal ethanol and heat it in a water bath to 60°C, add 20g of poloxamer until completely dissolved; under nitrogen protection, add 80g of Acanthopanax acanthopanax extract, 100g of phosphatidylserine, and 20g of pigeon brain extract , 165g poppy seed oil (unsaturated fatty acid content is 85% by weight) and 0.2g vitamin E, high-speed shearing to dissolve; Ethanol and moisture are removed under reduced pressure, stand-by as the content of soft capsule;

[0038] Prepare the soft capsule shell according to the following weight ratio: gelatin: purified water: glycerin: sorbitol: glycine: titanium dioxide=1:1:0.47:0.02:0.08:0.005 to carry out gelatinization, and the conventional manufacturing method is used to make pills, shape and dry, wash pills, dried pills, and picked pills to obtain Jiannao Compound Soft Capsule S-1 (no peculiar smell).

Embodiment 2

[0040] Based on 1000 capsules, take 300mL of medicinal ethanol and heat it in a water bath to 70°C, add 20g of poloxamer until completely dissolved; under nitrogen protection, add 100g of Acanthopanax acanthopanax extract, 100g of phosphatidylserine, and 10g of pigeon brain extract , 165g poppy seed oil (unsaturated fatty acid content is 85% by weight) and 0.2g vitamin E, high-speed shearing to dissolve; Ethanol and moisture are removed under reduced pressure, stand-by as the content of soft capsule;

[0041] Prepare the soft capsule shell according to the following weight ratio: gelatin: purified water: glycerin: sorbitol: glycine: titanium dioxide=1:1:0.47:0.02:0.08:0.005 to carry out gelatinization, and the conventional manufacturing method is used to make pills, shape and dry, wash pills, dried pills, and picked pills to obtain Jiannao Compound Soft Capsule S-2 (no peculiar smell).

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Abstract

The invention discloses a compound soft capsule containing an acanthopanax extract for strengthening the brain and a preparation method of the compound soft capsule. The method comprises the following steps: orderly dissolving the acanthopanax extract, mixed phospholipid and vegetable oil into an ethanol solution of poloxamer, removing ethanol to obtain content of the soft capsule; and encapsulating the content into a soft capsule shell, wherein the dosage of the mixed phospholipid is 90-240 parts by weight, the dosage of the vegetable oil is 140-300 parts by weight and the dosage of the poloxamer is 10-50 parts by weight relative to 100 parts of acanthopanax extract, the mixed phospholipid is prepared from an animal brain extract and adding ingredients, the weight ratio of the animal brain extract to the added ingredients is 1:(2-6) and the added ingredients comprise phosphatidylserine and / or dilinoleoyl phosphatidylcholine. The compound soft capsule for strengthening the brain, which is disclosed by the invention, can be effectively used for assisting improvement of memory, improvement of sleeping, and prevention of senile dementia, and has a good health-care effect.

Description

technical field [0001] The present invention relates to a brain-building compound soft capsule containing Acanthopanax extract and a preparation method thereof, in particular, to a method for preparing a brain-building compound soft capsule containing Acanthopanax extract and the method prepared Brain-invigorating compound soft capsules containing Acanthopanax extract. Background technique [0002] Syringin widely exists in Araliaceae plants, and has the functions of immune regulation, anti-tumor, anti-aging, anti-radiation damage and anti-fatigue, and can also treat cardiovascular and cerebrovascular diseases, diabetes and neurasthenia. Eleutherococcus senticosus is a common Araliaceae plant, which is recorded in Chinese herbal medical records. It is mainly used for spleen and kidney yang deficiency, physical weakness and fatigue, loss of appetite, soreness of the waist and knees, insomnia and dreaminess and other diseases. [0003] Animal brain extracts contain a variety...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/254A61K36/66A61K36/87A61K36/32A61K9/48A61P25/28A61P25/20A61K35/30
Inventor 陈曦侯琬实侯文阁
Owner 侯文阁
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