An analysis and evaluation method for the release process of a mixture substance group

Abstract

The invention belongs to the technical field of computer application, and relates to an analysis and evaluation method for the release process of a mixture substance group. Firstly, the project path is set through the project information management module and a new project is created; Import the test data into the computer memory, after the test data is imported, the substance group concentration and release calculation module will calculate the test data, and then the test data writing module will store the calculation results of the mixture substance group release process in the form of an Excel file. In the route, the final substance group concentration and release calculation evaluation analysis results visualization module uses the FusionCharts chart tool to display the line chart formed by the release and average release of the mixture substance group on the computer screen; the system used by it is simple in structure and composed of The principle is reliable, the analysis and evaluation speed is fast, the data is accurate, the application operation is convenient, the visibility is good, and the use environment is friendly.

Description

Technical field: [0001] The invention belongs to the field of computer application technology, and relates to a process for analyzing and evaluating the release process of multi-component substance groups of traditional pharmaceutical dosage forms and drug delivery systems by using a computer analysis and evaluation system, especially an analysis of the release process of a mixture substance group evaluation method. Background technique: [0002] At present, pharmaceutical preparations can be roughly divided into two types, one is chemical drug sustained and controlled release preparations with single or a small number of ingredients; In recent years, in the related research fields of pharmaceutical preparations, most of the methods still refer to the traditional chemical drug research mode of sustained and controlled release preparations with a single or a small number of index components, and this method is not suitable for dealing with Compound pharmaceutical preparations ...

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Problems solved by technology

[0002] At present, pharmaceutical preparations can be roughly divided into two types, one is chemical drug sustained and controlled release preparations with single or a small number of ingredients; In recent years, in the related research fields of pharmaceutical preparations, most of the methods still refer to the traditional chemical drug research mode of sustained and controlled release preparations with a single or a small number of index components, and this method is not suitable for dealing with Compound pharmaceutical preparations with multi-components and multi-pharmaceutical functions, usually in the form of tablets and pills, and generally solid dosage forms have release characteristics, which are beneficial to the body’s absorption. The release rate of such tablets and pills has not yet been established in my country. There is no direct standard for the more than 230 kinds of pills listed in the "Pharmacopia of the People's Republic of China" published in 2005, but the concentration and release rate indicators of the compound preparation drug substance group can reflect that the drug is absorbed by the body Therefore, the analysis and evaluation of the release rate of the multi-component substance group of the compound preparation of traditional Chinese medicine is the key direction of the development of traditional Chinese medicine in my country

[0003] The drug substance group refers to the collection of substances in a specific drug or drug compound preparation. For example, the substance group of the traditional Chinese medicine compound Danshen tablet refers to the collection of various medicinal substances contained in the compound Danshen tablet that can be absorbed by the organism, while the single medicinal material The substances contained in Salvia miltiorrhiza are Danshen substance groups. Obviously, the material composition, structure and function of these two drug substance groups are different. Compared with chemical medicines, compound drug preparations are composed of multi-flavor medicinal plants. The basis is relatively complex, and there are a lot of experimental data for the determination of the concentration of substance groups in traditional Chinese medicine compound preparations. Manual methods are used to analyze, process, evaluate and store the data, which is very labor-intensive and has low accuracy and work efficiency.

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