Analysis and evaluation method for releasing process of mixture chemome

Abstract

The invention belongs to the technical field of application of computers, and relates to an analysis and evaluation method for a releasing process of a mixture chemome. A project route is set through a project information management module and a new project is built; test data stored in an Excel file cell are introduced into the inner memory of a computer through a test data read-in module, the test data are calculated through a chemome concentration and release degree calculation module after being introduced, a test data write-in module stores the calculation result of the releasing process of the mixture chemome into the project route in an Excel file mode, and finally a chemome concentration and releasing degree calculation evaluation analysis result visualized module displays a line graph formed by the releasing degree and the average releasing degree of the mixture chemome onto the screen of the computer through a FusionCharts graph instrument. A system used in the method is simple in structure, reliable in composition principle, high in analysis and evaluation speed, accurate in data, flexible and convenient to apply and operate, good in visuality and friendly to the use environment.

Description

Technical field: [0001] The invention belongs to the technical field of computer applications, and relates to a process for analyzing and evaluating the release process of a traditional pharmaceutical dosage form and a multi-component substance group of a drug delivery system using a computer analysis and evaluation system, in particular to an analysis of the release process of a mixture substance group Evaluation method. Background technique: [0002] At present, pharmaceutical preparations can be roughly divided into two types, one is a chemical drug sustained and controlled release preparation with a single or a few ingredients; the other is a compound preparation of multi-component, multi-linked, multi-targeted Chinese patent medicine In recent years, in the related research fields of pharmaceutical preparations, most methods refer to the traditional chemical drug research mode of sustained and controlled release preparations with a single or a few index components, and this ...

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Problems solved by technology

[0002] At present, pharmaceutical preparations can be roughly divided into two types, one is chemical drug sustained and controlled release preparations with single or a small number of ingredients; In recent years, in the related research fields of pharmaceutical preparations, most of the methods still refer to the traditional chemical drug research mode of sustained and controlled release preparations with a single or a small number of index components, and this method is not suitable for dealing with Compound pharmaceutical preparations with multi-components and multi-pharmaceutical functions, usually in the form of tablets and pills, and generally solid dosage forms have release characteristics, which are beneficial to the body’s absorption. The release rate of such tablets and pills has not yet been established in my country. There is no direct standard for the more than 230 kinds of pills listed in the "Pharmacopia of the People's Republic of China" published in 2005, but the concentration and release rate indicators of the compound preparation drug substance group can reflect that the drug is absorbed by the body Therefore, the analysis and evaluation of the release rate of the multi-component substance group of the compound preparation of traditional Chinese medicine is the key direction of the development of traditional Chinese medicine in my country

[0003] The drug substance group refers to the collection of substances in a specific drug or drug compound preparation. For example, the substance group of the traditional Chinese medicine compound Danshen tablet refers to the collection of various medicinal substances contained in the compound Danshen tablet that can be absorbed by the organism, while the single medicinal material The substances contained in Salvia miltiorrhiza are Danshen substance groups. Obviously, the material composition, structure and function of these two drug substance groups are different. Compared with chemical medicines, compound drug preparations are composed of multi-flavor medicinal plants. The basis is relatively complex, and there are a lot of experimental data for the determination of the concentration of substance groups in traditional Chinese medicine compound preparations. Manual methods are used to analyze, process, evaluate and store the data, which is very labor-intensive and has low accuracy and work efficiency.

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