Composite natural material medicinal membrane for treating periodontitis and manufacturing method thereof

Abstract

The invention discloses a composite natural material medicinal membrane for treating periodontitis and a manufacturing method thereof, belonging to the field of medicine. The medicinal membrane is prepared from raw materials consisting of, by mass, an extraction concentrate of 16 to 23 parts of dried Rabdosia serra, a water decoction concentrate of 1 to 3 parts of dried honeysuckle flower, a water decoction concentrate of 3 to 5 parts of licorice, a raw juice concentrate of 60 to 70 parts of fresh aloe, 3 to 5 parts of coptis powder, 1 to 3 parts of pearl powder, 1 to 3 parts of scorpion powder, 1 to 3 parts of water-soluble chitosan and 1 to 3 parts of natural glycerin through mixing, heating, stirring for homogenization, membrane making, drying, membrane removal and slicing and packaging. The medicinal membrane uses natural materials or biological preparations, has bacteriostatic, antiviral, anti-inflammatory, detoxifying and pain easing effects and the like, has the excellent characteristics of safety, no stimulation, etc., exerts a special effect on treatment of periodontitis, is applicable to treatment of periodontitis through combination with mechanical scaling and avoids consequences like generation of drug-resistant microflora, adverse reaction of a whole body and the like caused by long-term usage of antibiotics.

Description

technical field [0001] The invention relates to a periodontitis medicinal film made of composite natural materials and biological materials, in particular to a composite natural material medicinal film for treating periodontitis. Background technique [0002] Periodontal disease is one of the two most common diseases in the human oral cavity, including gingivitis and periodontitis, which have a high prevalence worldwide. According to Du Jiandong, 80%-97% of adults in my country currently % suffer from different degrees of periodontal disease. According to Shen Jiaping, the prevalence of gingivitis is 75.04%-99.67%, and the prevalence of periodontitis is 20%-25%. Periodontal disease is the most prevalent chronic infectious disease in the population and the number one cause of tooth loss in adults. At the same time, periodontal disease can also cause a variety of systemic diseases, such as cardiovascular and respiratory diseases, stomach problems, endocarditis, or accelerated ...

AI Technical Summary

Problems solved by technology

Although mechanical plaque removal can eliminate and reduce the number of bacteria or disturb the biofilm structure of bacteria, it has shortcomings: first, the inhibition of bacterial toxins and metabolites by mechanical methods is still limited; second, some deep periodontal pockets , the curettage instrument is difficult to reach the bottom of the bag, and the treatment effect is not ideal

Therefore, the use of antibacterial drugs to maintain a relatively sustained antibacterial effect after scaling is an important auxiliary means, but the antibiotics used for routine clinical systemic use have many disadvantages: ①Periodontitis is a mixed infection of various microorganisms, and it is difficult to treat it by drug sensitivity Tests to determine the special antibiotics; ②Long-term use of large doses can easily cause bacterial flora imbalance and induce drug-resistant strains; ③The concentration of drugs reaching the periodontal area is low, and it is difficult to enter the biofilm; ④10%-30% of cases have gastrointestinal reactions , systemic allergies, and even nervous system symptoms, etc., which affect the physical and mental health of patients; ⑤ curative effect is affected by the compliance of patients

The local administration methods of gargling, coating, and local washing are not easy to cause bacterial resistance and have little side effects, but they often stay in the local area for a short time, and it is difficult to reach the subgingival area by gargling.